Publications by authors named "Dominik Schaer"

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Haptoglobin and Hemopexin Redirect Heme-Driven Oxidative Stress and Neurotoxicity in Organotypic Brain Slices.
Anna-Lea T Stalder, Raphael M Buzzi, Florence Vallelian, Dominik J Schaer

ACS Chem Neurosci· January 2026

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Stress-NRF2 response axis polarizes tumor macrophages and undermines immunotherapy.
Dominik J Schaer, Nadja Schulthess-Lutz, Livio Baselgia, Kahrisan Kunasingam, Rok Humar

J Immunother Cancer· October 2025

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Patterns of hemolysis, erythropoiesis, and iron distribution define unique disease trajectories in three mouse models of genetic anemia.
Irina L Dubach, Raphael M Buzzi, Dominik J Schaer, Florence Vallelian

Exp Hematol· July 2025

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Haptoglobin Attenuates Cerebrospinal Fluid Hemoglobin-Induced Neurological Deterioration in Sheep.
Bart R Thomson, Nina Schwendinger, Katrin Beckmann, Thomas Gentinetta, Daniel Couto, Dominik J Schaer

Transl Stroke Res· June 2025

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Navigating Hemolysis and the Renal Implications of Hemoglobin Toxicity in Cardiac Surgery.
Dominik J Schaer, Christian A Schaer, Rok Humar, Florence Vallelian, Reney Henderson

Anesthesiology· December 2024

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C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury.
Kevin Akeret, Bart R Thomson, Subhajit Ghosh, Marc Nolte, Urs Fischer, Dominik J Schaer

Fluids Barriers CNS· November 2024

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Effect of a nurse-led integrated care intervention on quality of life and rehospitalisation in patients with severe exacerbation of COPD-a pilot study.
Gabriela Schmid-Mohler, Christine Hübsch, Julia Braun, Claudia Steurer-Stey, Celine Aregger, Dominik J Schaer

Chron Respir Dis· October 2024

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Mitochondrial Elongation and ROS-Mediated Apoptosis in Prostate Cancer Cells under Therapy with Apalutamide and Complex I Inhibitor.
Valentin Baumgartner, Dominik Schaer, Holger Moch, Souzan Salemi, Daniel Eberli

Int J Mol Sci· June 2024

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Hemorrhage-activated NRF2 in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance.
Dominik J Schaer, Nadja Schulthess-Lutz, Livio Baselgia, Kerstin Hansen, Raphael M Buzzi

J Clin Invest· December 2023

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Clinical potential of automated convolutional neural network-based hematoma volumetry after aneurysmal subarachnoid hemorrhage.
Bart R Thomson, Firat Gürlek, Raphael M Buzzi, Nina Schwendinger, Emanuela Keller, Dominik J Schaer

J Stroke Cerebrovasc Dis· November 2023

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Targeting Metabolic Vulnerabilities to Overcome Prostate Cancer Resistance: Dual Therapy with Apalutamide and Complex I Inhibition.
Valentin Baumgartner, Dominik Schaer, Daniel Eberli, Souzan Salemi

Cancers (Basel)· November 2023

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VEXAS Syndrome With Tracheal Involvement but Absence of Vasculitis in FDG PET/CT.
Niklas Lohaus, Jan Schaab, Dominik Schaer, Stefan Balabanov, Martin W Huellner

Clin Nucl Med· September 2023

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Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation.
Ian Galea, Soham Bandyopadhyay, Diederik Bulters, Rok Humar, Michael Hugelshofer, Dominik J Schaer

Stroke· July 2023

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Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity.
Bart R Thomson, Henning Richter, Kevin Akeret, Raphael M Buzzi, Vania Anagnostakou, Dominik J Schaer

J Stroke Cerebrovasc Dis· March 2023

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Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.
Marc Emmenegger, Elena De Cecco, David Lamparter, Raphaël P B Jacquat, Julien Riou, Dominik J Schaer

iScience· February 2023

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Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity.
Marc Pfefferlé, Irina L Dubach, Raphael M Buzzi, Elena Dürst, Nadja Schulthess-Lutz, Dominik J Schaer

J Immunother Cancer· January 2023

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Association between iron deficiency and hospitalization rate in community-dwelling older adults: A 3-year prospective observational study of DO-HEALTH.
Caroline de Godoi Rezende Costa Molino, Laurence Woll, Maud Wieczorek, Lauren A Abderhalden, Patricia Lanz, Dominik J Schaer

Am J Clin Nutr· January 2023

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MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage.
Kevin Akeret, Raphael M Buzzi, Bart R Thomson, Nina Schwendinger, Jan Klohs, Dominik J Schaer

J Neuroinflammation· December 2022

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Erythrophagocytes in hemolytic anemia, wound healing, and cancer.
Rok Humar, Dominik J Schaer, Florence Vallelian

Trends Mol Med· November 2022

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Hemolysis, free hemoglobin toxicity, and scavenger protein therapeutics.
Florence Vallelian, Paul W Buehler, Dominik J Schaer

Blood· October 2022

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Prevalence and incidence of iron deficiency in European community-dwelling older adults: an observational analysis of the DO-HEALTH trial.
Alenka Stahl-Gugger, Caroline de Godoi Rezende Costa Molino, Maud Wieczorek, Patricia O Chocano-Bedoya, Lauren A Abderhalden, Dominik J Schaer

Aging Clin Exp Res· September 2022

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The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease.
Naja Nyffenegger, Rahima Zennadi, Natarajaswamy Kalleda, Anna Flace, Giada Ingoglia, Dominik J Schaer

Blood· August 2022

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A model to visualize the fate of iron after intracranial hemorrhage using isotopic tracers and elemental bioimaging.
Patrick Bücker, Raphael M Buzzi, Kevin Akeret, Leila Mosberger, Henning Richter, Dominik J Schaer

Metallomics· August 2022

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The HeMoVal study protocol: a prospective international multicenter cohort study to validate cerebrospinal fluid hemoglobin as a monitoring biomarker for aneurysmal subarachnoid hemorrhage related secondary brain injury.
Kevin Akeret, Raphael M Buzzi, Moritz Saxenhofer, Kathrin Bieri, Deborah Chiavi, Dominik J Schaer

BMC Neurol· July 2022

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Spatial transcriptome data from coronal mouse brain sections after striatal injection of heme and heme-hemopexin.
Kevin Akeret, Michael Hugelshofer, Dominik J Schaer, Raphael M Buzzi

Data Brief· April 2022

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