Publications by authors named "Don Cleveland"

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Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes.
Ksenia Krupina, Alexander Goginashvili, Michael W Baughn, Stephen Moore, Christopher D Steele, Don W Cleveland

Science· December 2025

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TDP-43 skein-like inclusions are formed by BAG3- and HSP70-guided co-aggregation with actin-binding proteins.
Shan Lu, Sitao Zhang, Spencer Oung, Jolene K Diedrich, Peng Han, Don W Cleveland

Nat Cell Biol· November 2025

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Author Correction: A two-step mechanism for epigenetic specification of centromere identity and function.
Daniele Fachinetti, H Diego Folco, Yael Nechemia-Arbely, Luis P Valente, Kristen Nguyen, Don W Cleveland

Nat Cell Biol· July 2025

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Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin.
Melinda S Beccari, Olatz Arnold-Garcia, Michael W Baughn, Jonathan W Artates, Melissa McAlonis-Downes, Don W Cleveland

Proc Natl Acad Sci U S A· May 2025

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Aberrant splicing in Huntington's disease accompanies disrupted TDP-43 activity and altered m6A RNA modification.
Thai B Nguyen, Ricardo Miramontes, Carlos Chillon-Marinas, Roy Maimon, Sonia Vazquez-Sanchez, Don W Cleveland

Nat Neurosci· February 2025

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CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis.
Vivian I Ko, Kailee Ong, Deborah Y Kwon, Xueying Li, Alicia Pietrasiewicz, Don W Cleveland

Acta Neuropathol Commun· December 2024

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CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.
Vivian I Ko, Kailee Ong, Don W Cleveland, Haiyang Yu, John M Ravits

Neurobiol Dis· June 2024

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Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.
Sonia Vazquez-Sanchez, Britt Tilkin, Fatima Gasset-Rosa, Sitao Zhang, Diana Piol, Don W Cleveland

Mol Neurodegener· June 2024

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Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.
Sonia Vazquez-Sanchez, Britt Tilkin, Fatima Gasset-Rosa, Sitao Zhang, Diana Piol, Don W Cleveland

bioRxiv· June 2024

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A phage nucleus-associated RNA-binding protein is required for jumbo phage infection.
Eray Enustun, Emily G Armbruster, Jina Lee, Sitao Zhang, Brian A Yee, Don W Cleveland

Nucleic Acids Res· May 2024

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Scrambling the genome in cancer: causes and consequences of complex chromosome rearrangements.
Ksenia Krupina, Alexander Goginashvili, Don W Cleveland

Nat Rev Genet· March 2024

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Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation.
Jone López-Erauskin, Mariana Bravo-Hernandez, Maximiliano Presa, Michael W Baughn, Ze'ev Melamed, Don W Cleveland

Nat Neurosci· January 2024

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Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease.
Ana Rita Agra Almeida Quadros, Zhaozhi Li, Xue Wang, I Sandra Ndayambaje, Sandeep Aryal, Don W Cleveland

Acta Neuropathol· January 2024

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Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates.
Peng Gao, Qi Zhang, Devin Keely, Don W Cleveland, Yihong Ye

J Med Chem· November 2023

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Aberrant splicing in Huntington's disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification.
Thai B Nguyen, Ricardo Miramontes, Carlos Chillon-Marinas, Roy Maimon, Sonia Vazquez-Sanchez, Don W Cleveland

bioRxiv· November 2023

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A phage nucleus-associated RNA-binding protein is required for jumbo phage infection.
Eray Enustun, Emily G Armbruster, Jina Lee, Sitao Zhang, Brian A Yee, Don W Cleveland

bioRxiv· September 2023

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GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells.
Moira A McMahon, Meghdad Rahdar, Swagatam Mukhopadhyay, Huynh-Hoa Bui, Christopher Hart, Don W Cleveland

Mol Ther Nucleic Acids· June 2023

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Mitotic tethering enables inheritance of shattered micronuclear chromosomes.
Prasad Trivedi, Christopher D Steele, Franco K C Au, Ludmil B Alexandrov, Don W Cleveland

Nature· June 2023

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Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats.
Julia Su Zhou Li, Ammal Abbasi, Dong Hyun Kim, Scott M Lippman, Ludmil B Alexandrov, Don W Cleveland

Nature· April 2023

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Mechanism of cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies.
Michael W Baughn, Ze'ev Melamed, Jone López-Erauskin, Melinda S Beccari, Karen Ling, Don W Cleveland

Science· March 2023

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Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of disease.
Melanie Jambeau, Kevin D Meyer, Marian Hruska-Plochan, Ricardos Tabet, Chao-Zong Lee, Don W Cleveland

Proc Natl Acad Sci U S A· December 2022

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A reference human induced pluripotent stem cell line for large-scale collaborative studies.
Caroline B Pantazis, Andrian Yang, Erika Lara, Justin A McDonough, Cornelis Blauwendraat, Don W Cleveland

Cell Stem Cell· December 2022

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Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition.
Shan Lu, Jiaojiao Hu, Olubankole Aladesuyi Arogundade, Alexander Goginashvili, Sonia Vazquez-Sanchez, Don W Cleveland

Nat Cell Biol· September 2022

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Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.
Sandra Diaz-Garcia, Vivian I Ko, Sonia Vazquez-Sanchez, Ruth Chia, Olubankole Aladesuyi Arogundade, Don Cleveland

Acta Neuropathol· December 2021

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Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation.
Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa McAlonis-Downes, Stéphane Dieterle, Salim Megat, Don W Cleveland

Mol Neurodegener· September 2021

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