Publications by authors named "Donald Bergstrom"

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Comparison of treatments for equine laryngeal hemiplegia using computational fluid dynamic analysis in an equine head model.
Michelle L Tucker, David G Wilson, Donald J Bergstrom, James L Carmalt

Front Vet Sci· December 2024

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Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Andreas Varkaris, Ermira Pazolli, Hakan Gunaydin, Qi Wang, Levi Pierce, Donald A Bergstrom

Cancer Discov· February 2024

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Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2.
Heike Schönherr, Pelin Ayaz, Alexander M Taylor, Jessica B Casaletto, B Barry Touré, Donald A Bergstrom

Proc Natl Acad Sci U S A· February 2024

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RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.
Vivek Subbiah, Vaibhav Sahai, Dejan Maglic, Kamil Bruderek, B Barry Touré, Donald A Bergstrom

Cancer Discov· September 2023

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Computational fluid dynamic analysis of upper airway procedures in equine larynges.
Michelle L Tucker, David G Wilson, Donald J Bergstrom, James L Carmalt

Front Vet Sci· April 2023

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Dolaflexin: A Novel Antibody-Drug Conjugate Platform Featuring High Drug Loading and a Controlled Bystander Effect.
Aleksandr V Yurkovetskiy, Natalya D Bodyak, Mao Yin, Joshua D Thomas, Susan M Clardy, Donald A Bergstrom

Mol Cancer Ther· May 2021

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The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b.
Natalya D Bodyak, Rebecca Mosher, Aleksandr V Yurkovetskiy, Mao Yin, Charlie Bu, Donald A Bergstrom

Mol Cancer Ther· May 2021

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Construction and optimization of gene expression signatures for prediction of survival in two-arm clinical trials.
Joachim Theilhaber, Marielle Chiron, Jennifer Dreymann, Donald Bergstrom, Jack Pollard

BMC Bioinformatics· July 2020

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Novel, Self-Assembling Dimeric Inhibitors of Human β Tryptase.
Sarah F Giardina, Douglas S Werner, Maneesh Pingle, Philip B Feinberg, Kenneth W Foreman, Donald E Bergstrom

J Med Chem· March 2020

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A Novel, Nonpeptidic, Orally Active Bivalent Inhibitor of Human β-Tryptase.
Sarah F Giardina, Douglas S Werner, Maneesh Pingle, Donald E Bergstrom, Lee D Arnold

Pharmacology· December 2018

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Target-Directed Self-Assembly of Homodimeric Drugs Against β-Tryptase.
Sarah F Giardina, Douglas S Werner, Maneesh Pingle, Kenneth W Foreman, Donald E Bergstrom

ACS Med Chem Lett· August 2018

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Reversible linkage of two distinct small molecule inhibitors of Myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines.
Jutta Wanner, Darlene Romashko, Douglas S Werner, Earl W May, Yue Peng, Donald E Bergstrom

PLoS One· January 2016

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Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Manoel Nunes, Patricia Vrignaud, Sophie Vacher, Sophie Richon, Astrid Lièvre, Donald Bergstrom

Cancer Res· April 2015

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Differential antitumor activity of aflibercept and bevacizumab in patient-derived xenograft models of colorectal cancer.
Marielle Chiron, Rebecca G Bagley, Jack Pollard, Parminder K Mankoo, Christophe Henry, Donald A Bergstrom

Mol Cancer Ther· June 2014

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Repeatability of quantitative FDG-PET/CT and contrast-enhanced CT in recurrent ovarian carcinoma: test-retest measurements for tumor FDG uptake, diameter, and volume.
Andrea G Rockall, Norbert Avril, Raymond Lam, Robert Iannone, P David Mozley, Donald Bergstrom

Clin Cancer Res· May 2014

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4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs.
Vida Zohrabi-Kalantari, Abbas Jarrahian, Caterina Bissantz, Donald E Bergstrom, Eric L Barker

Med Chem· September 2013

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Preface: insights into an unsolved problem in drug delivery.
Donald E Bergstrom, Alexander Wei

J Control Release· December 2012

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1,2,4-trisubstituted cyclopentanes as platforms for diversity.
Yousheng Guan, Caterina Bissantz, Donald E Bergstrom, Andreas Link

Arch Pharm (Weinheim)· September 2012

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Evaluation of end-capped DNA modules for pRNA capture and functionalization.
Brian M Laing, Donald E Bergstrom

Bioconjug Chem· April 2012

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Label-free imaging of semiconducting and metallic carbon nanotubes in cells and mice using transient absorption microscopy.
Ling Tong, Yuxiang Liu, Bridget D Dolash, Yookyung Jung, Mikhail N Slipchenko, Donald E Bergstrom

Nat Nanotechnol· December 2011

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Optimized method for the synthesis and purification of adenosine--folic acid conjugates for use as transcription initiators in the preparation of modified RNA.
Brian M Laing, Peixuan Guo, Donald E Bergstrom

Methods· June 2011

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Silicon field effect transistors as dual-use sensor-heater hybrids.
Bobby Reddy, Oguz H Elibol, Pradeep R Nair, Brian R Dorvel, Felice Butler, Donald E Bergstrom

Anal Chem· February 2011

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Properties of double-stranded oligonucleotides modified with lipophilic substituents.
Brian M Laing, Lisa Barrow-Laing, Maureen Harrington, Eric C Long, Donald E Bergstrom

Bioconjug Chem· August 2010

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Synthesis and evaluation of new spacers for use as dsDNA end-caps.
Pei-Sze Ng, Brian M Laing, Ganesan Balasundarum, Maneesh Pingle, Alan Friedman, Donald E Bergstrom

Bioconjug Chem· August 2010

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Genome-wide analysis of palindrome formation.
Scott J Diede, Hisashi Tanaka, Donald A Bergstrom, Meng-Chao Yao, Stephen J Tapscott

Nat Genet· April 2010

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