Publications by authors named "Donald J Foster"

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High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination.
Yesseinia I Anglero-Rodriguez, Florian A Lempp, Megha Subramanian, James McIninch, Mark K Schlegel, Donald J Foster

Nucleic Acids Res· January 2025

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RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Nadine Haase, Donald J Foster, Mark W Cunningham, Julia Bercher, Tuyen Nguyen

J Clin Invest· June 2020

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5'-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger.
Pawan Kumar, Rubina G Parmar, Christopher R Brown, Jennifer L S Willoughby, Donald J Foster

Chem Commun (Camb)· April 2019

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Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity.
Joel M Harp, Dale C Guenther, Anna Bisbe, Lydia Perkins, Shigeo Matsuda, Donald J Foster

Nucleic Acids Res· September 2018

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Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates.
Donald J Foster, Christopher R Brown, Sarfraz Shaikh, Casey Trapp, Mark K Schlegel

Mol Ther· March 2018

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Facile Synthesis, Geometry, and 2'-Substituent-Dependent in Vivo Activity of 5'-(E)- and 5'-(Z)-Vinylphosphonate-Modified siRNA Conjugates.
Rubina Giare Parmar, Christopher R Brown, Shigeo Matsuda, Jennifer L S Willoughby, Christopher S Theile, Donald J Foster

J Med Chem· February 2018

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4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing.
Elise Malek-Adamian, Dale C Guenther, Shigeo Matsuda, Saúl Martínez-Montero, Ivan Zlatev, Donald J Foster

J Am Chem Soc· October 2017

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Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
Mark K Schlegel, Donald J Foster, Alexander V Kel'in, Ivan Zlatev, Anna Bisbe

J Am Chem Soc· June 2017

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Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis.
James S Butler, Amy Chan, Susete Costelha, Shannon Fishman, Jennifer L S Willoughby, Donald J Foster

Amyloid· June 2016

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5'-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates.
Rubina Parmar, Jennifer L S Willoughby, Jingxuan Liu, Donald J Foster, Benjamin Brigham

Chembiochem· June 2016

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5'-C-Malonyl RNA: Small Interfering RNAs Modified with 5'-Monophosphate Bioisostere Demonstrate Gene Silencing Activity.
Ivan Zlatev, Donald J Foster, Jingxuan Liu, Klaus Charisse, Benjamin Brigham

ACS Chem Biol· April 2016

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Functional neuroimaging of dressing-related skills.
George F Wittenberg, Christopher T Lovelace, Donald J Foster, Joseph A Maldjian

Brain Imaging Behav· September 2014

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Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo.
Donald J Foster, Scott Barros, Rick Duncan, Sarfraz Shaikh, William Cantley

RNA· March 2012

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Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter.
Masayuki Matsui, Fuminori Sakurai, Sayda Elbashir, Donald J Foster, Muthiah Manoharan

Chem Biol· December 2010

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Atomoxetine enhances a short-term model of plasticity in humans.
Donald J Foster, David C Good, Allison Fowlkes, Lumy Sawaki

Arch Phys Med Rehabil· February 2006

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