Publications by authors named "Donatella Labella"

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Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity.
Dante Rotili, Domenico Tarantino, Biagina Marrocco, Christina Gros, Véronique Masson, Donatella Labella

PLoS One· June 2015

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Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts.
Sergio Valente, Veronica Rodriguez, Ciro Mercurio, Paola Vianello, Bruna Saponara, Donatella Labella

Eur J Med Chem· April 2015

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New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors.
Christina Gros, Laurence Fleury, Virginie Nahoum, Céline Faux, Sergio Valente, Donatella Labella

J Biol Chem· March 2015

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Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies.
Sergio Valente, Veronica Rodriguez, Ciro Mercurio, Paola Vianello, Bruna Saponara, Donatella Labella

ACS Med Chem Lett· February 2015

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1,3,4-Oxadiazole-containing histone deacetylase inhibitors: anticancer activities in cancer cells.
Sergio Valente, Daniela Trisciuoglio, Teresa De Luca, Angela Nebbioso, Donatella Labella

J Med Chem· July 2014

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Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.
Sergio Valente, Yiwei Liu, Michael Schnekenburger, Clemens Zwergel, Sandro Cosconati, Donatella Labella

J Med Chem· February 2014

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Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.
Dante Rotili, Stefano Tomassi, Mariarosaria Conte, Rosaria Benedetti, Marcello Tortorici, Donatella Labella

J Med Chem· January 2014

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tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells.
Sergio Valente, Daniela Trisciuoglio, Maria Tardugno, Rosaria Benedetti, Donatella Labella

ChemMedChem· May 2013

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An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases.
Anup K Upadhyay, Dante Rotili, Ji Woong Han, Ruogu Hu, Yanqi Chang, Donatella Labella

J Mol Biol· February 2012

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