Publications by authors named "Douglas McCarty"

Claim this Profile
P
Production of rAAV by plasmid transfection induces antiviral and inflammatory responses in suspension HEK293 cells.
Cheng-Han Chung, Christopher M Murphy, Vincent P Wingate, Jeffrey W Pavlicek, Reiko Nakashima, Douglas McCarty

Mol Ther Methods Clin Dev· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective.
Denise E Sabatino, Frederic D Bushman, Randy J Chandler, Ronald G Crystal, Beverly L Davidson, Douglas M McCarty

Mol Ther· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Durability of transgene expression after rAAV gene therapy.
Manish Muhuri, Daniel I Levy, Martin Schulz, Douglas McCarty, Guangping Gao

Mol Ther· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biodistribution and Tolerability of AAV-PHP.B-CBh- in Wistar Han Rats and Cynomolgus Macaques Reveal Different Toxicologic Profiles.
Xavier Palazzi, Ingrid D Pardo, Madhu P Sirivelu, Leah Newman, Steven W Kumpf, Douglas McCarty

Hum Gene Ther· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Topics in AAV integration come front and center at ASGCT AAV Integration Roundtable.
Denise E Sabatino, Douglas M McCarty

Mol Ther· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Immunogenicity and inflammatory properties of respiratory syncytial virus attachment G protein in cotton rats.
Margaret E Martinez, Cristina Capella Gonzalez, Devra Huey, Mark E Peeples, Douglas McCarty

PLoS One· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting Root Cause by Systemic scAAV9-h Gene Delivery: Functional Correction and Reversal of Severe MPS II in Mice.
Haiyan Fu, Kim Zaraspe, Naoko Murakami, Aaron S Meadows, Ricardo J Pineda, Douglas M McCarty

Mol Ther Methods Clin Dev· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Differential Prevalence of Antibodies Against Adeno-Associated Virus in Healthy Children and Patients with Mucopolysaccharidosis III: Perspective for AAV-Mediated Gene Therapy.
Haiyan Fu, Aaron S Meadows, Ricardo J Pineda, Krista L Kunkler, Kristen V Truxal, Douglas M McCarty

Hum Gene Ther Clin Dev· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Serum global metabolomics profiling reveals profound metabolic impairments in patients with MPS IIIA and MPS IIIB.
Haiyan Fu, Aaron S Meadows, Ricardo J Pineda, Robert P Mohney, Steve Stirdivant, Douglas M McCarty

Metab Brain Dis· October 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Near-Complete Correction of Profound Metabolomic Impairments Corresponding to Functional Benefit in MPS IIIB Mice after IV rAAV9-hNAGLU Gene Delivery.
Haiyan Fu, Aaron S Meadows, Tierra Ware, Robert P Mohney, Douglas M McCarty

Mol Ther· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effective Depletion of Pre-existing Anti-AAV Antibodies Requires Broad Immune Targeting.
Victoria M Velazquez, Aaron S Meadows, Ricardo J Pineda, Marybeth Camboni, Douglas M McCarty

Mol Ther Methods Clin Dev· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crossing the blood-brain-barrier with viral vectors.
Haiyan Fu, Douglas M McCarty

Curr Opin Virol· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional correction of neurological and somatic disorders at later stages of disease in MPS IIIA mice by systemic scAAV9-hSGSH gene delivery.
Haiyan Fu, Marcela P Cataldi, Tierra A Ware, Kimberly Zaraspe, Aaron S Meadows, Douglas M McCarty

Mol Ther Methods Clin Dev· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Blood genome-wide transcriptional profiles reflect broad molecular impairments and strong blood-brain links in Alzheimer's disease.
Bartholomew J Naughton, F Jason Duncan, Darren A Murrey, Aaron S Meadows, David E Newsom, Douglas M Mccarty

J Alzheimers Dis· January 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A GLP-Compliant Toxicology and Biodistribution Study: Systemic Delivery of an rAAV9 Vector for the Treatment of Mucopolysaccharidosis IIIB.
Aaron S Meadows, F Jason Duncan, Marybeth Camboni, Kathryn Waligura, Chrystal Montgomery, Douglas M McCarty

Hum Gene Ther Clin Dev· December 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Broad functional correction of molecular impairments by systemic delivery of scAAVrh74-hSGSH gene delivery in MPS IIIA mice.
F Jason Duncan, Bartholomew J Naughton, Kimberly Zaraspe, Darren A Murrey, Aaron S Meadows, Douglas M McCarty

Mol Ther· April 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Amyloidosis, synucleinopathy, and prion encephalopathy in a neuropathic lysosomal storage disease: the CNS-biomarker potential of peripheral blood.
Bartholomew J Naughton, F Jason Duncan, Darren Murrey, Tierra Ware, Aaron Meadows, Douglas M McCarty

PLoS One· September 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Feasibility and safety of systemic rAAV9-hNAGLU delivery for treating mucopolysaccharidosis IIIB: toxicology, biodistribution, and immunological assessments in primates.
Darren A Murrey, Bartholomew J Naughton, F Jason Duncan, Aaron S Meadows, Tierra A Ware, Douglas M McCarty

Hum Gene Ther Clin Dev· June 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Peripheral nervous system neuropathology and progressive sensory impairments in a mouse model of Mucopolysaccharidosis IIIB.
Haiyan Fu, Julianne D Bartz, Robert L Stephens, Douglas M McCarty

PLoS One· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Patterns of scAAV vector insertion associated with oncogenic events in a mouse model for genotoxicity.
Lucia E Rosas, Jessica L Grieves, Kimberly Zaraspe, Krista Md La Perle, Haiyan Fu, Douglas M McCarty

Mol Ther· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rapid transgene expression in multiple precursor cell types of adult rat subventricular zone mediated by adeno-associated type 1 vectors.
Olivier Bockstael, Catherine Melas, Catherine Pythoud, Marc Levivier, Douglas McCarty

Hum Gene Ther· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction of neurological disease of mucopolysaccharidosis IIIB in adult mice by rAAV9 trans-blood-brain barrier gene delivery.
Haiyan Fu, Julianne Dirosario, Smruti Killedar, Kimberly Zaraspe, Douglas M McCarty

Mol Ther· June 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Differential distribution of heparan sulfate glycoforms and elevated expression of heparan sulfate biosynthetic enzyme genes in the brain of mucopolysaccharidosis IIIB mice.
Douglas M McCarty, Julianne DiRosario, Kadra Gulaid, Smruti Killedar, Arie Oosterhof

Metab Brain Dis· March 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Restoration of central nervous system alpha-N-acetylglucosaminidase activity and therapeutic benefits in mucopolysaccharidosis IIIB mice by a single intracisternal recombinant adeno-associated viral type 2 vector delivery.
Haiyan Fu, Julianne DiRosario, Lu Kang, Joseph Muenzer, Douglas M McCarty

J Gene Med· July 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response.
Smruti Killedar, Julianne Dirosario, Erin Divers, Phillip G Popovich, Douglas M McCarty

J Neuroinflammation· July 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis