Publications by authors named "Duke M. Fitch"

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Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor-Prolyl Hydroxylase Inhibitor for Anemia.
Jennifer L Ariazi, Kevin J Duffy, David F Adams, Duke M Fitch, Lusong Luo

J Pharmacol Exp Ther· December 2017

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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.
Xiangping Qian, Andrew McDonald, Han-Jie Zhou, Nicholas D Adams, Cynthia A Parrish, Duke M Fitch

ACS Med Chem Lett· April 2010

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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors.
Rosanna Tedesco, Deping Chai, Michael G Darcy, Dashyant Dhanak, Duke M Fitch

Bioorg Med Chem Lett· August 2009

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Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase.
Antony N Shaw, Rosanna Tedesco, Ramesh Bambal, Deping Chai, Nestor O Concha, Duke M Fitch

Bioorg Med Chem Lett· August 2009

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3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Rosanna Tedesco, Antony N Shaw, Ramesh Bambal, Deping Chai, Nestor O Concha, Duke M Fitch

J Med Chem· February 2006

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A highly efficient, asymmetric synthesis of benzothiadiazine-substituted tetramic acids: potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Duke M Fitch, Karen A Evans, Deping Chai, Kevin J Duffy

Org Lett· November 2005

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Enantioselective Synthesis of the Elaiophylin Aglycon.
David A. Evans, Duke M. Fitch

J Org Chem· February 1997

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