Publications by authors named "Dwight Winters"

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Reduction of monoclonal antibody viscosity using interpretable machine learning.
Emily K Makowski, Hsin-Ting Chen, Tiexin Wang, Lina Wu, Jie Huang, Dwight Winters

MAbs· March 2024

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Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies.
Marissa Mock, Alex W Jacobitz, Christopher James Langmead, Athena Sudom, Daniel Yoo, Dwight Winters

MAbs· November 2023

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A High-Throughput Automated Protein Folding System.
Kenneth W Walker, Philip An, Dwight Winters

Methods Mol Biol· March 2020

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Development of BioRad NGC and GE ÄKTA pure systems for highly automated three column protein purification employing tandem affinity, buffer exchange and size exclusion chromatography.
Dwight Winters, Mai Tran, Daniel Yoo, Kenneth W Walker

Protein Expr Purif· January 2020

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Immunoaffinity capture coupled with capillary electrophoresis - mass spectrometry to study therapeutic protein stability in vivo.
Mei Han, Josh T Pearson, Yunan Wang, Dwight Winters, Marcus Soto

Anal Biochem· December 2017

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A Novel Fc-FGF21 With Improved Resistance to Proteolysis, Increased Affinity Toward β-Klotho, and Enhanced Efficacy in Mice and Cynomolgus Monkeys.
Shanaka Stanislaus, Randy Hecht, Junming Yie, Todd Hager, Michael Hall, Dwight Winters

Endocrinology· May 2017

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Automated high-throughput dense matrix protein folding screen using a liquid handling robot combined with microfluidic capillary electrophoresis.
Philip An, Dwight Winters, Kenneth W Walker

Protein Expr Purif· April 2016

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Automated two-step chromatography using an ÄKTA equipped with in-line dilution capability.
Dwight Winters, Carolyn Chu, Kenneth Walker

J Chromatogr A· December 2015

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Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes.
Randy Hecht, Yue-Sheng Li, Jeonghoon Sun, Ed Belouski, Michael Hall, Dwight Winters

PLoS One· June 2013

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Targeted codon optimization improves translational fidelity for an Fc fusion protein.
Katariina M Hutterer, Zhongqi Zhang, Mark Leo Michaels, Ed Belouski, Robert W Hong, Dwight Winters

Biotechnol Bioeng· November 2012

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A novel anion-exchange resin suitable for both discovery research and clinical manufacturing purposes.
Amir Porat, Dwight Winters, Ling Cai, Steve Smith, Frank Abroson

Prep Biochem Biotechnol· October 2012

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FGF21 N- and C-termini play different roles in receptor interaction and activation.
Junming Yie, Randy Hecht, Jennifer Patel, Jennitte Stevens, Wei Wang, Dwight Winters

FEBS Lett· January 2009

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Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.
Magdalena Wisniewska, Peter Goettig, Klaus Maskos, Edward Belouski, Dwight Winters

J Mol Biol· September 2008

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