Publications by authors named "Elena Helman"

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A Blood-based Assay for Assessment of Tumor Mutational Burden in First-line Metastatic NSCLC Treatment: Results from the MYSTIC Study.
Han Si, Michael Kuziora, Katie J Quinn, Elena Helman, Jiabu Ye

Clin Cancer Res· March 2021

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Baseline Plasma Tumor Mutation Burden Predicts Response to Pembrolizumab-based Therapy in Patients with Metastatic Non-Small Cell Lung Cancer.
Charu Aggarwal, Jeffrey C Thompson, Austin L Chien, Katie J Quinn, Wei-Ting Hwang, Elena Helman

Clin Cancer Res· May 2020

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Establishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends of Cancer Research TMB Harmonization Project.
Diana M Merino, Lisa M McShane, David Fabrizio, Vincent Funari, Shu-Jen Chen, Elena Helman

J Immunother Cancer· March 2020

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Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.
Kevin K Lin, Maria I Harrell, Amit M Oza, Ana Oaknin, Isabelle Ray-Coquard, Elena Helman

Cancer Discov· February 2019

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Cell-Free DNA Next-Generation Sequencing Prediction of Response and Resistance to Third-Generation EGFR Inhibitor.
Elena Helman, Minh Nguyen, Chris A Karlovich, Darrin Despain, A Karin Choquette

Clin Lung Cancer· November 2018

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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
Jennifer A Perry, Adam Kiezun, Peter Tonzi, Eliezer M Van Allen, Scott L Carter, Elena Helman

Proc Natl Acad Sci U S A· December 2014

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Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing.
Elena Helman, Michael S Lawrence, Chip Stewart, Carrie Sougnez, Gad Getz

Genome Res· July 2014

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Mutational heterogeneity in cancer and the search for new cancer-associated genes.
Michael S Lawrence, Petar Stojanov, Paz Polak, Gregory V Kryukov, Kristian Cibulskis, Elena Helman

Nature· July 2013

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Absolute quantification of somatic DNA alterations in human cancer.
Scott L Carter, Kristian Cibulskis, Elena Helman, Aaron McKenna, Hui Shen

Nat Biotechnol· May 2012

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A geometric approach for classification and comparison of structural variants.
Suzanne Sindi, Elena Helman, Ali Bashir, Benjamin J Raphael

Bioinformatics· June 2009

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