Publications by authors named "Elisabeth Gardiner"

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Phase 1b study of batiraxcept in combination with durvalumab in patients with platinum-resistant ovarian cancer.
Anne Knisely, Emily M Hinchcliff, Elisabeth Gardiner, Reshma Rangwala, Kathryn Lito

iScience· May 2024

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The Discovery of Exarafenib (KIN-2787): Overcoming the Challenges of Pan-RAF Kinase Inhibition.
Young K Chen, Toufike Kanouni, Lee D Arnold, Jason M Cox, Elisabeth Gardiner

J Med Chem· February 2024

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Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations.
John S Tyhonas, Lee D Arnold, Jason M Cox, Aleksandra Franovic, Elisabeth Gardiner

J Med Chem· February 2024

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Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage.
Na Wei, Yi Shi, Lan N Truong, Kathleen M Fisch, Tao Xu, Elisabeth Gardiner

Mol Cell· October 2014

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Human tRNA synthetase catalytic nulls with diverse functions.
Wing-Sze Lo, Elisabeth Gardiner, Zhiwen Xu, Ching-Fun Lau, Feng Wang

Science· July 2014

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Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.
Robert L Davis, Mehmet Kahraman, Thomas J Prins, Yan Beaver, Travis G Cook, Elisabeth M M Gardiner

Bioorg Med Chem Lett· June 2010

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Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis.
Kersi N Pestonjamasp, Carol Forster, Chunxiang Sun, Elisabeth M Gardiner, Ben Bohl

Blood· October 2006

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Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.
Mary R Stofega, Luraynne C Sanders, Elisabeth M Gardiner, Gary M Bokoch

Mol Biol Cell· June 2004

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Spatial and temporal analysis of Rac activation during live neutrophil chemotaxis.
Elisabeth M Gardiner, Kersi N Pestonjamasp, Benjamin P Bohl, Chester Chamberlain, Klaus M Hahn

Curr Biol· December 2002

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