Publications by authors named "Ellen Welch"

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Splicing Modulators as a Therapeutic Strategy for Tauopathies.
M Catarina Silva, Hannah Lindmeier, Paolo Pigini, Jennifer Laughlin, Yong Yu, Ellen M Welch

bioRxiv· May 2025

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The honourable doctor-let us learn from this book and listen to those who speak up.
Ellen Welch

BMJ· April 2025

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Uncertain future of GP partnerships in England.
Ayan Panja, Ellen Welch, Steve Taylor, Paul Evans

BMJ· April 2025

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Preclinical studies of gene replacement therapy for CDKL5 deficiency disorder.
Gregory Voronin, Jana Narasimhan, Jamila Gittens, Josephine Sheedy, Philip Lipari, Ellen M Welch

Mol Ther· October 2024

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Comparison of pharmaceutical properties and biological activities of prednisolone, deflazacort, and vamorolone in DMD disease models.
Grace Liu, Philip Lipari, Anna Mollin, Stephen Jung, Irina Teplova, Ellen Welch

Hum Mol Genet· January 2024

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Quantitation of Pax-6 protein in ocular impression cytology samples using an electrochemiluminescence immunoassay.
Phillip G Zaworski, Rachel Schwartz, Jeffrey Burr, Daniel Skutnik, Anna Mollin, Ellen Welch

Anal Biochem· November 2022

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Guanidino quinazolines and pyrimidines promote readthrough of premature termination codons in cells with native nonsense mutations.
Christie Morrill, Westley J Friesen, Suresh Babu, Ramil Y Baiazitov, Wu Du, Ellen M Welch

Bioorg Med Chem Lett· November 2022

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GP crisis requires more than just technology to fix it.
Simon Hodes, Shan Hussain, Helen Salisbury, Ellen Welch, Phil Whitaker

BMJ· July 2022

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When part time means full time: the GP paradox.
Simon Hodes, Shan Hussain, Ayan Panja, Ellen Welch, Rosie Shire

BMJ· May 2022

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Time for change: widening participation in the UKFPO foundation programme.
Freya Rhodes, Ayan Basu, Ellen Welch

BMJ· March 2022

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In vitro metabolism, pharmacokinetics and drug interaction potentials of emvododstat, a DHODH inhibitor.
Jiyuan Ma, Diksha Kaushik, Shirley Yeh, Valerie Northcutt, John Babiak, Ellen M Welch

Xenobiotica· February 2022

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What implications does the Toombes vs Mitchell case have for other healthcare professionals?
Ellen Welch, Jenny Vaughan, Kristina Rebecca Cranfield, Roshana Mehdian

BMJ· January 2022

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SMN protein is required throughout life to prevent spinal muscular atrophy disease progression.
Xin Zhao, Zhihua Feng, Nicole Risher, Anna Mollin, Josephine Sheedy, Ellen Welch

Hum Mol Genet· December 2021

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Supporting NHS staff facing abuse from patients frustrated by long waits for care.
Amit Sinha, Ghulam Abbas, Shabi Ahmad, Ramesh Mehta, Ellen Welch

BMJ· November 2021

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Ataluren metabolism: Ataluren-O-1β-acyl glucuronide is a stable circulating metabolite in mouse, rat, dog and human.
Jiyuan Ma, Nicole Risher, Valerie Northcutt, Young-Choon Moon, Marla Weetall, Ellen Welch

Drug Metab Pharmacokinet· June 2021

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Corrigendum to: Pharmacologically-induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset.
Zhihua Feng, Karen K Y Ling, Xin Zhao, Chunyi Zhou, Gary Karp, Ellen M Welch

Hum Mol Genet· May 2021

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The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.
Jeremy Luban, Rachel A Sattler, Elke Mühlberger, Jason D Graci, Liangxian Cao, Ellen M Welch

Virus Res· January 2021

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Chemical modifications of G418 (geneticin): Synthesis of novel readthrough aminoglycosides results in an improved in vitro safety window but no improvements in vivo.
Ramil Y Baiazitov, Westley Friesen, Briana Johnson, Anna Mollin, Josephine Sheedy, Ellen Welch

Carbohydr Res· September 2020

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The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines.
Jeremy Luban, Rachel Sattler, Elke Mühlberger, Jason D Graci, Liangxian Cao, Ellen M Welch

bioRxiv· August 2020

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In vitro metabolism, reaction phenotyping, enzyme kinetics, CYP inhibition and induction potential of ataluren.
Ronald Kong, Jiyuan Ma, Seongwoo Hwang, Young-Choon Moon, Ellen M Welch

Pharmacol Res Perspect· April 2020

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Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin-deficient muscles through matrix metalloproteinases.
Irina Kramerova, Chino Kumagai-Cresse, Natalia Ermolova, Ekaterina Mokhonova, Masha Marinov, Ellen Welch

Hum Mol Genet· October 2019

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The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
Westley J Friesen, Briana Johnson, Jairo Sierra, Jin Zhuo, Priya Vazirani, Ellen M Welch

PLoS One· April 2019

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New Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery.
Martin Y Ng, Haibo Zhang, Amy Weil, Vijay Singh, Ryan Jamiolkowski, Ellen Welch

ACS Med Chem Lett· December 2018

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The nucleoside analog clitocine is a potent and efficacious readthrough agent.
Westley J Friesen, Christopher R Trotta, Yuki Tomizawa, Jin Zhuo, Briana Johnson, Ellen M Welch

RNA· April 2017

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Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.
Bijoyita Roy, Westley J Friesen, Yuki Tomizawa, John D Leszyk, Jin Zhuo, Ellen M Welch

Proc Natl Acad Sci U S A· November 2016

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