Publications by authors named "Emmanuel Pfund"

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Synthesis of New DltA Inhibitors and Their Application as Adjuvant Antibiotics to Re-Sensitize Methicillin-Resistant .
David Leparfait, Alexandre Mahé, Xiao Feng, Delphine Coupri, Fabien Le Cavelier, Emmanuel Pfund

Molecules· June 2025

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D-alanylation of lipoteichoic acids inhibitor provides anti-virulence and anti-resistance effects against methicillin-resistant .
Alexandre Mahé, Nicolas Verneuil, Delphine Coupri, Axel Hartke, Vincent Cattoir, Emmanuel Pfund

Antimicrob Agents Chemother· May 2025

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Stereoselective Ring-Opening Reaction of α-Fluorinated Oxetanes: A Practical and Theoretical Investigation.
David Leparfait, Thibault Thierry, Nicola L da Rocha, Rémi Legay, Emmanuel Pfund

J Org Chem· December 2024

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Expanding the Scope of Group Transfer Radical Reaction: Toward the Synthesis of Fluorinated Nucleoside Analogues Incorporating Difluorophosphonylated Allylic Ether Moieties.
Aurore Ceuninck, Thierry Lequeux, Emmanuel Pfund

J Org Chem· June 2024

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Photocatalyzed Hydroaminodifluoroalkylation of Alkenes.
Pierre Fossé, Emmanuel Pfund, Thierry Lequeux

Chemistry· October 2023

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Convergent access to mono-fluoroalkene-based peptidomimetics.
Florent Larnaud, Charlène Calata, Anaïs Prunier, Clothilde Le Guen, Rémi Legay, Emmanuel Pfund

Org Biomol Chem· February 2022

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Inhibition of d-alanylation of teichoic acids overcomes resistance of methicillin-resistant Staphylococcus aureus.
Delphine Coupri, Nicolas Verneuil, Axel Hartke, Axelle Liebaut, Thierry Lequeux, Emmanuel Pfund

J Antimicrob Chemother· October 2021

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Metal-Free Aminomethylation of Aromatic Sulfones Promoted by Eosin Y.
Thibault Thierry, Emmanuel Pfund, Thierry Lequeux

Chemistry· October 2021

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Selective preparation of tetrasubstituted fluoroalkenes by fluorine-directed oxetane ring-opening reactions.
Clément Q Fontenelle, Thibault Thierry, Romain Laporte, Emmanuel Pfund, Thierry Lequeux

Beilstein J Org Chem· August 2020

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Genetic and pharmacological inactivation of d-alanylation of teichoic acids sensitizes pathogenic enterococci to β-lactams.
Delphine Coupri, Aurélie Budin-Verneuil, Axel Hartke, Abdellah Benachour, Loïc Léger, Emmanuel Pfund

J Antimicrob Chemother· November 2019

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Difluorophosphonylated Allylic Ether Moiety as a 2'-Modification of RNA-Type Molecules: Synthesis, Thermal, and Metabolic Studies.
Emmanuel Pfund, Christelle Dupouy, Sonia Rouanet, Rémi Legay, Cyril Lebargy

Org Lett· June 2019

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Photoinduced Nonstabilized Azomethine Ylide Formation for the Preparation of Fluorine Containing Pyrrolidines.
Thibault Thierry, Cyril Lebargy, Emmanuel Pfund, Thierry Lequeux

J Org Chem· May 2019

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Access to Fluoropyrrolidines by Intramolecular Aza-Michael Addition Reaction.
Clothilde Le Guen, Minh-Loan Tran Do, Aurélien Chardon, Cyril Lebargy, Jean-François Lohier, Emmanuel Pfund

J Org Chem· August 2016

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Fluorinated hydroxypiperidines as selective β-glucosidase inhibitors.
Clothilde Le Guen, Teresa Mena-Barragán, Carmen Ortiz Mellet, David Gueyrard, Emmanuel Pfund

Org Biomol Chem· June 2015

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Synthesis of fluorinated agonist of sphingosine-1-phosphate receptor 1.
Lucie Aliouane, Sovy Chao, Leyre Brizuela, Emmanuel Pfund, Olivier Cuvillier

Bioorg Med Chem· September 2014

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Synthesis of substituted exo-glucals via a modified Julia olefination and identification as selective β-glucosidase inhibitors.
Samuel Habib, Florent Larnaud, Emmanuel Pfund, Teresa Mena Barragán, Thierry Lequeux

Org Biomol Chem· January 2014

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Aza-Michael access to fluoroalkylidene analogues of biomolecules.
Anaïs Prunier, Charlène Calata, Julien Legros, Jacques Maddaluno, Emmanuel Pfund

J Org Chem· August 2013

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Ready synthetic access to enantiopure allylic α(F)-branched fluoroalkenes.
Florent Larnaud, Julien Malassis, Emmanuel Pfund, Bruno Linclau, Thierry Lequeux

Org Lett· May 2013

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Fluorophosphonylated nucleoside derivatives as new series of thymidine phosphorylase multisubstrate inhibitors.
Sonia Amel Diab, Coralie De Schutter, Murielle Muzard, Richard Plantier-Royon, Emmanuel Pfund

J Med Chem· March 2012

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Toward the synthesis of benzothiazolyl fluoroaminosulfones.
Charlène Calata, Emmanuel Pfund, Thierry Lequeux

J Org Chem· December 2009

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Synthesis of fluorophosphonylated acyclic nucleotide analogues via copper(I)-catalyzed Huisgen 1-3 dipolar cycloaddition.
Sonia Amel Diab, Antje Hienzch, Cyril Lebargy, Stéphane Guillarme, Emmanuel Pfund

Org Biomol Chem· November 2009

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Efficient synthesis of fluorophosphonylated alkyles by ring-opening reaction of cyclic sulfates.
Sonia Amel Diab, Aboubacary Sene, Emmanuel Pfund, Thierry Lequeux

Org Lett· September 2008

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Transition state chirality and role of the vicinal hydroxyl in the ribosomal peptidyl transferase reaction.
Kevin S Huang, Nicolas Carrasco, Emmanuel Pfund, Scott A Strobel

Biochemistry· August 2008

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An uncharged amine in the transition state of the ribosomal peptidyl transfer reaction.
David A Kingery, Emmanuel Pfund, Rebecca M Voorhees, Kensuke Okuda, Ingo Wohlgemuth

Chem Biol· May 2008

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Modified Julia fluoroolefination: selective preparation of fluoroalkenoates.
Emmanuel Pfund, Cyril Lebargy, Jacques Rouden, Thierry Lequeux

J Org Chem· October 2007

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