Publications by authors named "Eric Parkhill"

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Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII).
Dmitry O Koltun, Eric Q Parkhill, Rao Kalla, Thao D Perry, Elfatih Elzein

Bioorg Med Chem Lett· February 2018

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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late Ii), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.
Jeff A Zablocki, Elfatih Elzein, Xiaofen Li, Dmitry O Koltun, Eric Q Parkhill

J Med Chem· October 2016

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Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazine.
Dmitry O Koltun, Eric Q Parkhill, Elfatih Elzein, Tetsuya Kobayashi, Robert H Jiang

Bioorg Med Chem Lett· July 2016

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Discovery of triazolopyridine GS-458967, a late sodium current inhibitor (Late INai) of the cardiac NaV 1.5 channel with improved efficacy and potency relative to ranolazine.
Dmitry O Koltun, Eric Q Parkhill, Elfatih Elzein, Tetsuya Kobayashi, Gregory T Notte

Bioorg Med Chem Lett· July 2016

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Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.
Dmitry O Koltun, Timur M Zilbershtein, Vasily A Migulin, Natalya I Vasilevich, Eric Q Parkhill

Bioorg Med Chem Lett· August 2009

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Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.
Dmitry O Koltun, Natalya I Vasilevich, Eric Q Parkhill, Andrei I Glushkov, Timur M Zilbershtein

Bioorg Med Chem Lett· June 2009

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Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors.
Dmitry O Koltun, Eric Q Parkhill, Natalya I Vasilevich, Andrei I Glushkov, Timur M Zilbershtein

Bioorg Med Chem Lett· April 2009

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Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists.
Elfatih Elzein, Rao Kalla, Xiaofen Li, Thao Perry, Eric Parkhill

Bioorg Med Chem Lett· January 2006

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