Publications by authors named "Thao Perry"

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Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII).
Dmitry O Koltun, Eric Q Parkhill, Rao Kalla, Thao D Perry, Elfatih Elzein, Jason K Perry

Bioorg Med Chem Lett· February 2018

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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late Ii), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.
Jeff A Zablocki, Elfatih Elzein, Xiaofen Li, Dmitry O Koltun, Eric Q Parkhill, Thao Perry, Jason Perry

J Med Chem· October 2016

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Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazine.
Dmitry O Koltun, Eric Q Parkhill, Elfatih Elzein, Tetsuya Kobayashi, Robert H Jiang, Thao D Perry

Bioorg Med Chem Lett· July 2016

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Discovery of triazolopyridine GS-458967, a late sodium current inhibitor (Late INai) of the cardiac NaV 1.5 channel with improved efficacy and potency relative to ranolazine.
Dmitry O Koltun, Eric Q Parkhill, Elfatih Elzein, Tetsuya Kobayashi, Gregory T Notte, Thao D Perry

Bioorg Med Chem Lett· July 2016

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Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases.
Elfatih Elzein, Rao V Kalla, Xiaofen Li, Thao Perry, Art Gimbel

J Med Chem· April 2008

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Selective, high affinity A(2B) adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl)xanthines.
Rao V Kalla, Elfatih Elzein, Thao Perry, Xiaofen Li, Art Gimbel

Bioorg Med Chem Lett· February 2008

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N6-Cycloalkyl-2-substituted adenosine derivatives as selective, high affinity adenosine A1 receptor agonists.
Elfatih Elzein, Rao Kalla, Xiaofen Li, Thao Perry, Tim Marquart

Bioorg Med Chem Lett· January 2007

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Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
Rao V Kalla, Elfatih Elzein, Thao Perry, Xiaofen Li, Venkata Palle

J Med Chem· June 2006

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Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists.
Elfatih Elzein, Rao Kalla, Xiaofen Li, Thao Perry, Eric Parkhill

Bioorg Med Chem Lett· January 2006

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The discovery of a selective, high affinity A(2B) adenosine receptor antagonist for the potential treatment of asthma.
Jeff Zablocki, Rao Kalla, Thao Perry, Venkata Palle, Vaibhav Varkhedkar

Bioorg Med Chem Lett· February 2005

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A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts.
Nandini Kishore, Cindy Sommers, Sumathy Mathialagan, Julia Guzova, Min Yao, Thao Perry

J Biol Chem· August 2003

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