Publications by authors named "Erick Morris"

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BH3 profiling as pharmacodynamic biomarker for the activity of BH3 mimetics.
Rongqing Aaron Pan, Youzhen Wang, Shumei Qiu, Mariana Villalobos-Ortiz, Jeremy Ryan, Erick Morris

Haematologica· April 2024

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Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance.
Jennifer L Cotton, Javier Estrada Diez, Vivek Sagar, Julie Chen, Michelle Piquet, Erick J Morris

Cancer Res· November 2023

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Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia.
Donia M Moujalled, Fiona C Brown, Chong Chyn Chua, Michael A Dengler, Giovanna Pomilio, Rhiannon Morris, Erick Morris

Blood· February 2023

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Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non-Small Cell Lung Cancer.
Alberto A Chiappori, Ben Creelan, Tawee Tanvetyanon, Jhanelle E Gray, Eric B Haura, Erick Morris

Clin Cancer Res· June 2022

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Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
Shruti Bhatt, Marissa S Pioso, Elyse Anne Olesinski, Binyam Yilma, Jeremy A Ryan, Erick Morris

Cancer Cell· December 2020

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Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia.
Donia M Moujalled, Giovanna Pomilio, Corina Ghiurau, Adam Ivey, Jessica Salmon, Erick Morris

Leukemia· April 2019

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S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Patrick Casara, James Davidson, Audrey Claperon, Gaëtane Le Toumelin-Braizat, Meike Vogler, Erick Morris

Oncotarget· April 2018

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High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells.
Thomas Horn, Stéphane Ferretti, Nicolas Ebel, Angela Tam, Samuel Ho, Erick Morris

Cancer Res· December 2016

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Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.
Bryan Severyn, Thi Nguyen, Michael D Altman, Lixia Li, Kumiko Nagashima, Erick Morris

J Biomol Screen· October 2016

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Dissecting Therapeutic Resistance to ERK Inhibition.
Sharda Jha, Erick J Morris, Alan Hruza, My Sam Mansueto, Gottfried K Schroeder

Mol Cancer Ther· April 2016

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Evaluating TBK1 as a therapeutic target in cancers with activated IRF3.
Asli Muvaffak, Qi Pan, Haiyan Yan, Rafael Fernandez, Jongwon Lim, Erick J Morris

Mol Cancer Res· July 2014

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Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.
Erick J Morris, Sharda Jha, Clifford R Restaino, Priya Dayananth, Hugh Zhu

Cancer Discov· July 2013

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E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8.
Erick J Morris, Jun-Yuan Ji, Fajun Yang, Luisa Di Stefano, Anabel Herr

Nature· September 2008

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E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage.
Nam-Sung Moon, Luisa Di Stefano, Erick J Morris, Reena Patel, Kristin White

PLoS Genet· August 2008

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The Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survival.
Xiaodong Wu, Megumu Yamada-Mabuchi, Erick J Morris, Pradeep Singh Tanwar, Leonard Dobens

Proc Natl Acad Sci U S A· April 2008

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Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.
Erick J Morris, William A Michaud, Jun-Yuan Ji, Nam-Sung Moon, James W Rocco

PLoS Genet· November 2006

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The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.
Yi Zhang, Dianbo Qu, Erick J Morris, Michael J O'Hare, Steven M Callaghan

J Neurosci· August 2006

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Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development.
Nam-Sung Moon, Maxim V Frolov, Eun-Jeong Kwon, Luisa Di Stefano, Dessislava K Dimova, Erick J Morris

Dev Cell· October 2005

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G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression.
Maxim V Frolov, Olivier Stevaux, Nam-Sung Moon, Dessislava Dimova, Eun-Jeong Kwon, Erick J Morris

Genes Dev· March 2003

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Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2.
Olivier Stevaux, Dessislava Dimova, Maxim V Frolov, Barbie Taylor-Harding, Erick Morris

EMBO J· September 2002

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