Publications by authors named "Eugene Rui"

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SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance.
Kristen Jensen-Pergakes, John Tatlock, Karen A Maegley, Indrawan J McAlpine, Michele McTigue, Eugene Rui

Mol Cancer Ther· January 2022

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Correction to Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors.
Pei-Pei Kung, Eugene Rui, Simon Bergqvist, Patrick Bingham, John Braganza

J Med Chem· December 2016

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Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors.
Pei-Pei Kung, Eugene Rui, Simon Bergqvist, Patrick Bingham, John Braganza

J Med Chem· September 2016

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Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressure.
Qinhua Huang, Eugene Y Rui, Morena Cobbs, Dac M Dinh, Hovhannes J Gukasyan

J Med Chem· March 2015

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2-(6-Bromo-3-pyrid-yl)-8-methyl-imidazo[1,2-a]pyrazine.
Buwen Huang, Eugene Rui, Martin Wythes, Pei-Pei Kung, Curtis Moore

Acta Crystallogr Sect E Struct Rep Online· June 2010

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Ocular pharmacokinetics and hypotensive activity of PF-04475270, an EP4 prostaglandin agonist in preclinical models.
Ganesh Prasanna, Jay Fortner, Cathie Xiang, Eric Zhang, Samantha Carreiro, Eugene Rui

Exp Eye Res· November 2009

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Characterization of the CHK1 allosteric inhibitor binding site.
Darin Vanderpool, Ted O Johnson, Chen Ping, Simon Bergqvist, Gordon Alton, Eugene Rui

Biochemistry· October 2009

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6-Methyl-sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one.
Quinhua Huang, Paul F Richardson, Eugene Rui, Arnold L Rheingold, Alex Yanovsky

Acta Crystallogr Sect E Struct Rep Online· September 2009

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Chemoenzymatic synthesis of small molecule human therapeutics.
Ningqing Ran, Eugene Rui, Jinhua Liu, Junhua Tao

Curr Pharm Des· March 2009

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