Publications by authors named "Ewa Prochniewicz"

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Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac muscle.
Piyali Guhathakurta, Lien A Phung, Ewa Prochniewicz, Sarah Lichtenberger, Anna Wilson

J Biol Chem· October 2020

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Actin-Myosin Interaction: Structure, Function and Drug Discovery.
Piyali Guhathakurta, Ewa Prochniewicz, David D Thomas

Int J Mol Sci· September 2018

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High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin-myosin structure and function.
Piyali Guhathakurta, Ewa Prochniewicz, Benjamin D Grant, Kurt C Peterson, David D Thomas

J Biol Chem· August 2018

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Phosphomimetic S3D cofilin binds but only weakly severs actin filaments.
W Austin Elam, Wenxiang Cao, Hyeran Kang, Andrew Huehn, Glen M Hocky, Ewa Prochniewicz

J Biol Chem· December 2017

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A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure.
Piyali Guhathakurta, Ewa Prochniewicz, Osha Roopnarine, John A Rohde, David D Thomas

Biophys J· July 2017

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Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chain.
Piyali Guhathakurta, Ewa Prochniewicz, David D Thomas

Proc Natl Acad Sci U S A· April 2015

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The structural dynamics of actin during active interaction with myosin depends on the isoform of the essential light chain.
Ewa Prochniewicz, Piyali Guhathakurta, David D Thomas

Biochemistry· March 2013

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Cardiac myosin binding protein-C restricts intrafilament torsional dynamics of actin in a phosphorylation-dependent manner.
Brett A Colson, Inna N Rybakova, Ewa Prochniewicz, Richard L Moss, David D Thomas

Proc Natl Acad Sci U S A· December 2012

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Allosteric communication in Dictyostelium myosin II.
Piyali Guhathakurta, Ewa Prochniewicz, Joseph M Muretta, Margaret A Titus, David D Thomas

J Muscle Res Cell Motil· October 2012

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Impacts of dystrophin and utrophin domains on actin structural dynamics: implications for therapeutic design.
Ava Yun Lin, Ewa Prochniewicz, Davin M Henderson, Bin Li, James M Ervasti

J Mol Biol· June 2012

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Actin filament dynamics in the actomyosin VI complex is regulated allosterically by calcium-calmodulin light chain.
Ewa Prochniewicz, Anaëlle Pierre, Brannon R McCullough, Harvey F Chin, Wenxiang Cao

J Mol Biol· October 2011

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Large-scale opening of utrophin's tandem calponin homology (CH) domains upon actin binding by an induced-fit mechanism.
Ava Y Lin, Ewa Prochniewicz, Zachary M James, Bengt Svensson, David D Thomas

Proc Natl Acad Sci U S A· August 2011

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Myosin isoform determines the conformational dynamics and cooperativity of actin filaments in the strongly bound actomyosin complex.
Ewa Prochniewicz, Harvey F Chin, Arnon Henn, Diane E Hannemann, Adrian O Olivares

J Mol Biol· February 2010

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Dystrophin and utrophin have distinct effects on the structural dynamics of actin.
Ewa Prochniewicz, Davin Henderson, James M Ervasti, David D Thomas

Proc Natl Acad Sci U S A· May 2009

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Changes in actin structural transitions associated with oxidative inhibition of muscle contraction.
Ewa Prochniewicz, Daniel Spakowicz, David D Thomas

Biochemistry· November 2008

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Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers.
Ewa Prochniewicz, Dawn A Lowe, Daniel J Spakowicz, LeeAnn Higgins, Kate O'Conor

Am J Physiol Cell Physiol· February 2008

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Age-related decline in actomyosin structure and function.
Ewa Prochniewicz, LaDora V Thompson, David D Thomas

Exp Gerontol· October 2007

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Structural dynamics of the actin-myosin interface by site-directed spectroscopy.
Vicci L Korman, Sarah E B Anderson, Ewa Prochniewicz, Margaret A Titus, David D Thomas

J Mol Biol· March 2006

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Cofilin increases the torsional flexibility and dynamics of actin filaments.
Ewa Prochniewicz, Neal Janson, David D Thomas, Enrique M De la Cruz

J Mol Biol· November 2005

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Age-related decline in actomyosin function.
Ewa Prochniewicz, David D Thomas, LaDora V Thompson

J Gerontol A Biol Sci Med Sci· April 2005

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Structural dynamics of actin during active interaction with myosin: different effects of weakly and strongly bound myosin heads.
Ewa Prochniewicz, Timothy F Walseth, David D Thomas

Biochemistry· August 2004

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Changes in actin and myosin structural dynamics due to their weak and strong interactions.
David D Thomas, Ewa Prochniewicz, Osha Roopnarine

Results Probl Cell Differ· September 2002

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