Publications by authors named "F Jenck"

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Anxiolytic-like effects of the dual orexin receptor antagonist daridorexant in rats.
Michel Alexander Steiner, Rebekka Locher, Hugues Lecourt, Francois Jenck

Neurosci Appl· March 2024

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From Oxadiazole to Triazole Analogues: Optimization toward a Dual Orexin Receptor Antagonist with Improved in vivo Efficacy in Dogs.
Christine Brotschi, Martin H Bolli, John Gatfield, Bibia Heidmann, Francois Jenck

ChemMedChem· March 2020

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Oxadiazole Derivatives as Dual Orexin Receptor Antagonists: Synthesis, Structure-Activity Relationships, and Sleep-Promoting Properties in Rats.
Christine Brotschi, Catherine Roch, John Gatfield, Alexander Treiber, Jodi T Williams, Francois Jenck

ChemMedChem· July 2019

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The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468.
Alexander Treiber, Ruben de Kanter, Catherine Roch, John Gatfield, Christoph Boss, Francois Jenck

J Pharmacol Exp Ther· September 2017

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Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold-Hopping Approach.
Bibia Heidmann, John Gatfield, Catherine Roch, Alexander Treiber, Simone Tortoioli, François Jenck

ChemMedChem· October 2016

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