Publications by authors named "Fabio Simoes"

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Structure-activity relationships of acid-hydrolyzed Carrageenans: Molecular modifications and anticancer activity in colorectal Cancer cells.
Ellen Cristina Miranda Lacerda, Lucas de Freitas Pedrosa, Francisco Felipe Bezerra, Paulo Antônio de Souza Mourão, Gabriela Martins de Araújo

Int J Biol Macromol· December 2025

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Development of a translational strategy for using TIMP-3 to inhibit aggrecanase activity in osteoarthritis.
Fabio A Simoes, Greg Scutt, Manuela Mengozzi, Simon A Mitchell, Jacob Keen

Osteoarthritis Cartilage· September 2025

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Computational modelling of aggressive B-cell lymphoma.
Eleanor S Jayawant, Aimilia Vareli, Andrea Pepper, Chris Pepper, Fabio Simoes

Biochem Soc Trans· August 2025

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Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL.
Aimilia Vareli, Haripriya Vaidehi Narayanan, Heather Clark, Eleanor Jayawant, Hui Zhou, Fabio Simoes

Cell Death Dis· August 2025

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Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL.
Aimilia Vareli, Haripriya Vaidehi Narayanan, Heather Clark, Eleanor Jayawant, Hui Zhou, Fabio Simoes

bioRxiv· February 2025

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Severe dynein dysfunction in cholinergic neurons exacerbates ALS-like phenotypes in a new mouse model.
Fabio A Simoes, Eleni Christoforidou, Raphaelle Cassel, Luc Dupuis, Majid Hafezparast

Biochim Biophys Acta Mol Basis Dis· January 2025

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A Novel In Vitro Model of the Bone Marrow Microenvironment in Acute Myeloid Leukemia Identifies CD44 and Focal Adhesion Kinase as Therapeutic Targets to Reverse Cell Adhesion-Mediated Drug Resistance.
Eleni E Ladikou, Kim Sharp, Fabio A Simoes, John R Jones, Thomas Burley

Cancers (Basel)· January 2025

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Exposure to microplastics contaminated with pharmaceuticals and personal care products: Histological effects on Ucides cordatus.
Letícia Fernanda da Silva, Caio Rodrigues Nobre, Beatriz Barbosa Moreno, Camilo Dias Seabra Pereira, Alexandre Rodrigo Nascimento Gonçalves

Sci Total Environ· December 2024

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Are Microfibers a Threat to Marine Invertebrates? A Sea Urchin Toxicity Assessment.
Jennifer Barbosa Dos Santos, Rodrigo Brasil Choueri, Francisco Eduardo Melo Dos Santos, Laís Adrielle de Oliveira Santos, Letícia Fernanda da Silva

Toxics· October 2024

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Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data.
Richard Norris, John Jones, Erika Mancini, Timothy Chevassut, Fabio A Simoes

Blood Cancer J· July 2024

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An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner.
Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon

Dis Model Mech· May 2024

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Single session subconvulsive electrical stimulation has rapid therapeutic effects and reduces length of hospitalization in patients in an acute manic episode.
Amilcar Silva-Dos-Santos, Nagy A Youssef, Joana Bravo, Miguel Sales, Maria Vaz Velho

Brain Stimul· November 2023

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Interactive effects of microplastics and benzo[a]pyrene on two species of marine invertebrates.
Tawany de Mello Souza, Rodrigo Brasil Choueri, Caio Rodrigues Nobre, Denis Moledo de Souza Abessa, Beatriz Barbosa Moreno

Mar Pollut Bull· August 2023

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Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43.
Eleni Christoforidou, Fabio A Simoes, David Gordon, Kevin Talbot, Majid Hafezparast

Amyotroph Lateral Scler Frontotemporal Degener· July 2023

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Potential of Non-Coding RNA as Biomarkers for Progressive Supranuclear Palsy.
Fabio A Simoes, Greig Joilin, Oliver Peters, Luisa-Sophie Schneider, Josef Priller

Int J Mol Sci· November 2022

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Incorporation of Hydrophilic Macrocycles Into Drug-Linker Reagents Produces Antibody-Drug Conjugates With Enhanced Performance.
Nick Evans, Ruslan Grygorash, Paul Williams, Andrew Kyle, Terrence Kantner, Fabio Simoes

Front Pharmacol· June 2022

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Comparison of Different Methods for Spongin-like Collagen Extraction from Marine Sponges ( and ): Physicochemical Properties and In Vitro Biological Analysis.
Tiago A T Araújo, Amanda de Souza, Alan F Santana, Anna Rafaela C Braga, Márcio R Custódio

Membranes (Basel)· July 2021

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Study of the interaction Cu(II) - Carbendazim in natural waters by electrochemical techniques.
Aymara da Silva Santos, Fábio Ruiz Simões, Lúcia Codognoto, Eliana Maíra Agostini Valle

Chemosphere· September 2020

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Modulation of drug-linker design to enhance in vivo potency of homogeneous antibody-drug conjugates.
Martin Pabst, William McDowell, Anaïs Manin, Andrew Kyle, Nicolas Camper, Fabio Simoes

J Control Release· May 2017

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Combinatorial Biomolecular Nanopatterning for High-Throughput Screening of Stem-Cell Behavior.
Yacoub Y I Amin, Kasper Runager, Fabio Simoes, Adam Celiz, Vincenzo Taresco

Adv Mater· February 2016

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Layer-by-layer films based on carbon nanotubes and polyaniline for detecting 2-chlorophenol.
Juliana S Silva, Anerise De Barros, Carlos J L Constantino, Fábio R Simões, Marystela Ferreira

J Nanosci Nanotechnol· September 2014

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Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD.
Danielle C Diaper, Yoshitsugu Adachi, Luke Lazarou, Max Greenstein, Fabio A Simoes

Hum Mol Genet· October 2013

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Invasive thymoma in a child: a rare case report.
Mauricio Murce Rocha, Precil Diego Miranda de Menezes Neves, Camila Cristina Martini Rodrigues, Guilherme Freire Angotti Carrara, Fábio Fonseca Simões

J Pediatr Surg· February 2012

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