Publications by authors named "Frances Hackman"

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Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Intravenous Infusions of PF-07304814 (Lufotrelvir) in Participants Hospitalized With COVID-19.
Philip Robinson, Sima S Toussi, Sudeepta Aggarwal, Arthur Bergman, Tong Zhu, Frances Hackman

Open Forum Infect Dis· August 2023

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Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.
Ravi Shankar P Singh, Gregory S Walker, Eugene P Kadar, Loretta M Cox, Heather Eng, Frances Hackman

Clin Pharmacol Ther· December 2022

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Safety, Tolerability, and Pharmacokinetics of Intravenous Doses of PF-07304814, a Phosphate Prodrug Protease Inhibitor for the Treatment of SARS-CoV-2, in Healthy Adult Participants.
Tong Zhu, Sylvester Pawlak, Sima S Toussi, Frances Hackman, Kimberly Thompson

Clin Pharmacol Drug Dev· December 2022

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Innovative Randomized Phase I Study and Dosing Regimen Selection to Accelerate and Inform Pivotal COVID-19 Trial of Nirmatrelvir.
Ravi Shankar P Singh, Sima S Toussi, Frances Hackman, Phylinda L Chan, Rohit Rao

Clin Pharmacol Ther· July 2022

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Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort.
Rachel J Church, Gerd A Kullak-Ublick, Jiri Aubrecht, Herbert L Bonkovsky, Naga Chalasani, Frances Hackman

Hepatology· February 2019

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Add-on histamine receptor-3 antagonist for allergic rhinitis: a double blind randomized crossover trial using the environmental exposure unit.
Michelle L North, Terry J Walker, Lisa M Steacy, Barnaby G Hobsbawn, Richard J Allan, Frances Hackman

Allergy Asthma Clin Immunol· July 2014

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Efficient assessment of efficacy in post-traumatic peripheral neuropathic pain patients: pregabalin in a randomized, placebo-controlled, crossover study.
Tim M Jenkins, Trevor S Smart, Frances Hackman, Carol Cooke, Keith Kc Tan

J Pain Res· October 2012

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The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms.
Jeffrey R Stokes, Francisco A Romero, Richard J Allan, Peter G Phillips, Frances Hackman

J Allergy Clin Immunol· February 2012

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Safety and tolerability of lersivirine, a nonnucleoside reverse transcriptase inhibitor, during a 28-day, randomized, placebo-controlled, Phase I clinical study in healthy male volunteers.
John Davis, Frances Hackman, Marie-Noella Ndongo, HengWee Choo, Drew Lewis

Clin Ther· October 2010

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Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection.
David A Cooper, Jayvant Heera, James Goodrich, Margaret Tawadrous, Michael Saag, Frances Hackman

J Infect Dis· March 2010

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Activity, pharmacokinetics and safety of lersivirine (UK-453,061), a next-generation nonnucleoside reverse transcriptase inhibitor, during 7-day monotherapy in HIV-1-infected patients.
Gerd Fätkenheuer, Schlomo Staszewski, Andreas Plettenburg, Frances Hackman, Gary Layton

AIDS· October 2009

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Effect of single doses of maraviroc on the QT/QTc interval in healthy subjects.
John D Davis, Frances Hackman, Gary Layton, Tracy Higgins, David Sudworth

Br J Clin Pharmacol· April 2008

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