Publications by authors named "Frank Coppo"

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Encoded library technology screening of hepatitis C virus NS4B yields a small-molecule compound series with in vitro replicon activity.
Christopher Arico-Muendel, Zhengrong Zhu, Hamilton Dickson, Derek Parks, Jesse Keicher, Frank Coppo

Antimicrob Agents Chemother· February 2016

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Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor.
Zining Wu, Todd L Graybill, Xin Zeng, Michael Platchek, Jean Zhang, Frank T Coppo

ACS Comb Sci· December 2015

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Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.
Jeremy S Disch, Ghotas Evindar, Cynthia H Chiu, Charles A Blum, Han Dai, Frank Coppo

J Med Chem· May 2013

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Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.
John Skidmore, Zeenat Atcha, Emmanuelle Boucherat, Laura Castelletti, Deborah W Chen, Frank T Coppo

Bioorg Med Chem Lett· May 2012

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The discovery of 2-fluoro-N-(3-fluoro-4-(5-((4-morpholinobutyl)amino)-1,3,4-oxadiazol-2-yl)phenyl)benzamide, a full agonist of the alpha-7 nicotinic acetylcholine receptor showing efficacy in the novel object recognition model of cognition enhancement.
John Skidmore, Zeenat Atcha, Emmanuelle Boucherat, Laura Castelletti, Deborah W Chen, Frank T Coppo

Bioorg Med Chem Lett· May 2012

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Amino acid anthranilamide derivatives as a new class of glycogen phosphorylase inhibitors.
Karen A Evans, Yue H Li, Frank T Coppo, Todd L Graybill, Maria Cichy-Knight

Bioorg Med Chem Lett· July 2008

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Characterization of an exosite binding inhibitor of matrix metalloproteinase 13.
Lata T Gooljarsingh, Ami Lakdawala, Frank Coppo, Lusong Luo, Gregg B Fields

Protein Sci· January 2008

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Synthesis and structure-activity relationships of 3-phenyl-2-propenamides as inhibitors of glycogen phosphorylase a.
Yue H Li, Frank T Coppo, Karen A Evans, Todd L Graybill, Mehul Patel

Bioorg Med Chem Lett· November 2006

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Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis.
Tianbao Lu, Thomas Markotan, Frank Coppo, Bruce Tomczuk, Carl Crysler

Bioorg Med Chem Lett· July 2004

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