Publications by authors named "Frederic Jung"

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Discovery of new quinoline ether inhibitors with high affinity and selectivity for PDGFR tyrosine kinases.
Patrick A Plé, Frédéric Jung, Sue Ashton, Laurent Hennequin, Romuald Laine

Bioorg Med Chem Lett· May 2012

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Discovery of AZD2932, a new Quinazoline Ether Inhibitor with high affinity for VEGFR-2 and PDGFR tyrosine kinases.
Patrick A Plé, Frédéric Jung, Sue Ashton, Laurent Hennequin, Romuald Laine

Bioorg Med Chem Lett· January 2012

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Novel imidazo[1,2-a]pyridine based inhibitors of the IGF-1 receptor tyrosine kinase: optimization of the aniline.
Richard Ducray, Clifford D Jones, Frederic H Jung, Iain Simpson, Jon Curwen

Bioorg Med Chem Lett· August 2011

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Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase.
Richard Ducray, Iain Simpson, Frederic H Jung, J Willem M Nissink, Peter W Kenny

Bioorg Med Chem Lett· August 2011

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Synthesis and SAR of 1-acetanilide-4-aminopyrazole-substituted quinazolines: selective inhibitors of Aurora B kinase with potent anti-tumor activity.
Kevin M Foote, Andrew A Mortlock, Nicola M Heron, Frédéric H Jung, George B Hill

Bioorg Med Chem Lett· March 2008

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AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis.
Robert W Wilkinson, Rajesh Odedra, Simon P Heaton, Stephen R Wedge, Nicholas J Keen, Frederic H Jung

Clin Cancer Res· June 2007

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Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase.
Andrew A Mortlock, Kevin M Foote, Nicola M Heron, Frédéric H Jung, Georges Pasquet

J Med Chem· May 2007

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SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors.
Nicola M Heron, Malcolm Anderson, David P Blowers, Jason Breed, Jonathan M Eden, Frederic H Jung

Bioorg Med Chem Lett· March 2006

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Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors.
Frédéric H Jung, Georges Pasquet, Christine Lambert-van der Brempt, Jean-Jacques M Lohmann, Nicolas Warin

J Med Chem· February 2006

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Progress in the development of selective inhibitors of aurora kinases.
Andrew A Mortlock, Nicholas J Keen, Frederic H Jung, Nicola M Heron, Kevin M Foote

Curr Top Med Chem· October 2005

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Progress in the development of selective inhibitors of Aurora kinases.
Andrew Mortlock, Nicholas J Keen, Frederic H Jung, Nicola M Heron, Kevin M Foote

Curr Top Med Chem· June 2005

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