Publications by authors named "Frederick Valeriote"

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Majusculamide-o, a simplified marine natural product analog, exhibits potent and specific cancer cell cytotoxicity.
Niklas Alexander Wahl, Naiara Lebrón-Acosta, Michelle Pérez-Cuevas, Angel Hernandez-Mejias, Dmitry Leshchiner, Frederick A Valeriote

Sci Rep· November 2025

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Further Probing the Properties of a Unique Sponge-derived Alkaloid Through the Isolation of a New (-)-(5)-(8)-(14)-Mycothiazole Analogue.
Joe A Gerke, Sofia F Odron, Juri Kim, Naibedya Dutta, Jacqueline G Clarke, Frederick A Valeriote

J Nat Prod· October 2024

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Novel Small Molecule, UTS-1401, as a Radioprotector for Total-Body Irradiation.
Frederick A Valeriote, Stephen L Brown, Joseph Media, Pin Li, Mani Maheshwari

Radiat Res· July 2024

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Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells.
Jitender Monga, Frederick Valeriote, Clara Hwang, Shirish Gadgeel, Jagadananda Ghosh

Mol Cancer Ther· March 2023

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Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a sp. Marine Cyanobacterium.
Ozlem Demirkiran, Jehad Almaliti, Tiago Leão, Gabriel Navarro, Tara Byrum, Frederick A Valeriote

J Nat Prod· August 2021

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Correction to "Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from sp.".
Eduardo J E Caro-Diaz, Frederick A Valeriote, William H Gerwick

Org Lett· August 2020

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Synthesis, Cytotoxicity, and Genotoxicity of 10-Aza-9-oxakalkitoxin, an ,,-Trisubstituted Hydroxylamine Analog, or Hydroxalog, of a Marine Natural Product.
Sandeep Dhanju, Kapil Upadhyaya, Christopher A Rice, Scott D Pegan, Joseph Media, Frederick A Valeriote

J Am Chem Soc· May 2020

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A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs.
Jennifer J Schmidt, Yogan Khatri, Scott I Brody, Catherine Zhu, Halina Pietraszkiewicz, Frederick A Valeriote

ACS Chem Biol· February 2020

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Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 Configuration.
Tyler A Johnson, Joseph D Morris, David A Coppage, Colon V Cook, Lauren N Persi, Frederick A Valeriote

ACS Med Chem Lett· February 2020

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The anti-MRSA compound 3-O-alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR) inhibits protein synthesis in Staphylococcus aureus.
Nicholas J Carruthers, Paul M Stemmer, Joe Media, Ken Swartz, Xiaojuan Wang, Frederick Valeriote

J Proteomics· January 2020

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Computationally Assisted Discovery and Assignment of a Highly Strained and PANC-1 Selective Alkaloid from Alaska's Deep Ocean.
Yike Zou, Xiaojuan Wang, James Sims, Bin Wang, Pankaj Pandey, Frederick A Valeriote

J Am Chem Soc· March 2019

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Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp.
Eduardo J E Caro-Diaz, Frederick A Valeriote, William H Gerwick

Org Lett· February 2019

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Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.
Jehad Almaliti, Bailey Miller, Halina Pietraszkiewicz, Evgenia Glukhov, C Benjamin Naman, Frederick A Valeriote

Eur J Med Chem· January 2019

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Computationally Assisted Assignment of the Kadsuraols, a Class of Chemopreventive Agents for the Control of Liver Cancer.
Xiaojuan Wang, Jiabao Liu, Pankaj Pandey, Frank R Fronczek, Robert J Doerksen, Frederick A Valeriote

Org Lett· September 2018

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The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells.
Nicholas Lorig-Roach, Frances Hamkins-Indik, Tyler A Johnson, Karen Tenney, Frederick A Valeriote

Tetrahedron· January 2018

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Investigation of the Physical and Bioactive Properties of Bromo- and Iodo-Containing Sponge-Derived Compounds Possessing an Oxyphenylethanamine Core.
Erin P McCauley, Hanh Lam, Nicholas Lorig-Roach, Justin Luu, Cameron Lloyd, Frederick A Valeriote

J Nat Prod· December 2017

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Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation.
Nicholas J Carruthers, Paul M Stemmer, Ben Chen, Frederick Valeriote, Xiaohua Gao

Eur J Pharmacol· September 2017

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Cytotoxic Phyllactone Analogs from the Marine Sponge Phyllospongia papyrecea.
Huawei Zhang, Phillip Crews, Karen Tenney, Frederick A Valeriote

Med Chem· August 2017

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Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium.
C Benjamin Naman, Ramandeep Rattan, Svetlana E Nikoulina, John Lee, Bailey W Miller, Frederick A Valeriote

J Nat Prod· March 2017

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Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues.
Sheng Lin, Erin P McCauley, Nicholas Lorig-Roach, Karen Tenney, Cassandra N Naphen, Frederick A Valeriote

Mar Drugs· March 2017

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Cytotoxic halogenated monoterpenes from Plocamium cartilagineum.
Omar M M Sabry, Douglas E Goeger, Frederick A Valeriote, William H Gerwick

Nat Prod Res· February 2017

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Mycotoxin verrucarin A inhibits proliferation and induces apoptosis in prostate cancer cells by inhibiting prosurvival Akt/NF-kB/mTOR signaling.
Yongbo Liu, Xiaohua Gao, Dorrah Deeb, Yiguan Zhang, Jiajiu Shaw, Frederick A Valeriote

J Exp Ther Oncol· November 2016

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The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling.
Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Yiguan Zhang, Jiajiu Shaw, Frederick A Valeriote

Int J Oncol· September 2016

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The anti-inflammatory peptide Ac-SDKP is released from thymosin-β4 by renal meprin-α and prolyl oligopeptidase.
Nitin Kumar, Pablo Nakagawa, Branislava Janic, Cesar A Romero, Morel E Worou, Frederick Valeriote

Am J Physiol Renal Physiol· May 2016

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HPLC Plasma Assay of a Novel Anti-MRSA Compound, Kaempferol-3-O-Alpha-L-(2",3"-di-p-coumaroyl)rhamnoside, from Sycamore Leaves.
Yiguan Zhang, Frederick Valeriote, Kenneth Swartz, Ben Chen, Mark T Hamann

Nat Prod Commun· August 2015

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