Publications by authors named "Gillian Griffiths"

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The MYO1F interactome reveals ASAP1, CD2AP and SH3KBP1 as novel adaptor proteins in podosomes and phagosomes.
Susan D Arden, Eva Pennink, András Lakatos, Gillian M Griffiths, Anna H Lippert

J Cell Sci· December 2025

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Nuclear polarization to the immune synapse facilitates an early transcriptional burst.
Yukako Asano, Claire Y Ma, Martin M Limback-Stokin, Adam M Rochussen, Jane C Stinchcombe, Gillian M Griffiths

Sci Immunol· September 2025

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Transcriptional adaptation after deletion of Cdc42 in primary T cells.
Adam M Rochussen, Claire Y Ma, Gillian M Griffiths

J Cell Sci· August 2025

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Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency.
Elena Blanco, Carme Camps, Sameer Bahal, Mohit D Kerai, Matteo P Ferla, Gillian M Griffiths

J Exp Med· January 2025

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Griscelli Syndrome Type 2: Comprehensive Analysis of 149 New and Previously Described Patients with RAB27A Deficiency.
Jesmeen Maimaris, Adriel Roa-Bautista, Mahreen Sohail, Claire Booth, Chiara Cugno, Gillian Griffiths

J Clin Immunol· November 2024

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Lipid switches in the immunological synapse.
Gillian Griffiths, Britta Brügger, Christian Freund

J Biol Chem· July 2024

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NFIL3 contributes to cytotoxic T lymphocyte-mediated killing.
Tiphaine Douanne, Katharina Strege, Martin Del Castillo Velasco-Herrera, Adam M Rochussen, David J Adams, Gillian M Griffiths

Open Biol· February 2024

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Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis.
Arianne C Richard, Claire Y Ma, John C Marioni, Gillian M Griffiths

EMBO Rep· November 2023

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Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism ( and vesicle trafficking .
Nina Brauer, Yuto Maruta, Miriam Lisci, Katharina Strege, Ilske Oschlies, Gillian M Griffiths

Front Immunol· July 2023

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Imaging the T-cell receptor: new approaches, new insights.
Adam M Rochussen, Anna H Lippert, Gillian M Griffiths

Curr Opin Immunol· June 2023

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Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse.
Jane C Stinchcombe, Yukako Asano, Christopher J G Kaufman, Kristin Böhlig, Christopher J Peddie, Gillian M Griffiths

Science· May 2023

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Arming a killer: mitochondrial regulation of CD8 T cell cytotoxicity.
Miriam Lisci, Gillian M Griffiths

Trends Cell Biol· February 2023

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Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Marcel P Trefny, Nicole Kirchhammer, Priska Auf der Maur, Marina Natoli, Dominic Schmid, Gillian M Griffiths

Nat Commun· February 2023

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Super-killer CTLs are generated by single gene deletion of Bach2.
Philippa R Barton, Alexander J Davenport, Jens Hukelmann, Doreen A Cantrell, Jane C Stinchcombe, Gillian M Griffiths

Eur J Immunol· November 2022

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Staggered starts in the race to T cell activation.
Arianne C Richard, Gordon L Frazer, Claire Y Ma, Gillian M Griffiths

Trends Immunol· November 2021

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Signal strength controls the rate of polarization within CTLs during killing.
Gordon L Frazer, Christian M Gawden-Bone, Nele M G Dieckmann, Yukako Asano, Gillian M Griffiths

J Cell Biol· October 2021

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Mitochondrial translation is required for sustained killing by cytotoxic T cells.
Miriam Lisci, Philippa R Barton, Lyra O Randzavola, Claire Y Ma, Julia M Marchingo, Gillian M Griffiths

Science· October 2021

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Cytoskeletal control of the secretory immune synapse.
Tiphaine Douanne, Gillian M Griffiths

Curr Opin Cell Biol· August 2021

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Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement.
Yuta Ohishi, Sandra Ammann, Vahid Ziaee, Katharina Strege, Miriam Groß, Gillian M Griffiths

Front Immunol· June 2021

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Teasing out function from morphology: Similarities between primary cilia and immune synapses.
Tiphaine Douanne, Jane C Stinchcombe, Gillian M Griffiths

J Cell Biol· June 2021

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A new direction for Traffic.
Michael S Marks, Robert G Parton, Trina A Schroer, Sharon A Tooze, Frances M Brodsky, Gillian M Griffiths

Traffic· December 2020

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Stimulation strength controls the rate of initiation but not the molecular organisation of TCR-induced signalling.
Claire Y Ma, John C Marioni, Gillian M Griffiths, Arianne C Richard

Elife· May 2020

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High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.
Lucie Abeler-Dörner, Adam G Laing, Anna Lorenc, Dmitry S Ushakov, Simon Clare, Mark Griffiths, Gillian M Griffiths

Nat Immunol· January 2020

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Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy.
Oisín Huhn, Martin A Ivarsson, Lucy Gardner, Mike Hollinshead, Jane C Stinchcombe, Gillian Griffiths

Nat Commun· January 2020

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Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.
Lyra O Randzavola, Katharina Strege, Marie Juzans, Yukako Asano, Jane C Stinchcombe, Gillian M Griffiths

J Clin Invest· December 2019

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