Publications by authors named "Ginny D Ho"

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Bioavailable pyrrolo-benzo-1,4-diazines as Na(v)1.7 sodium channel blockers for the treatment of pain.
Shu-Wei Yang, Ginny D Ho, Deen Tulshian, Ana Bercovici, Zheng Tan, Xiaoping Zhou

Bioorg Med Chem Lett· November 2014

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Discovery of pyrrolo-benzo-1,4-diazines as potent Na(v)1.7 sodium channel blockers.
Ginny D Ho, Deen Tulshian, Ana Bercovici, Zheng Tan, Jennifer Hanisak, Xiaoping Zhou

Bioorg Med Chem Lett· September 2014

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The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia.
Ginny D Ho, W Michael Seganish, Ana Bercovici, Deen Tulshian, William J Greenlee, Robert Hodgson

Bioorg Med Chem Lett· April 2012

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Pyrazoloquinolines as PDE10A inhibitors: discovery of a tool compound.
William T McElroy, Zheng Tan, Kallol Basu, Shu-Wei Yang, Jennifer Smotryski, Ginny D Ho, Robert Hodgson

Bioorg Med Chem Lett· February 2012

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The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia.
Ginny D Ho, Shu-Wei Yang, Jennifer Smotryski, Ana Bercovici, Terry Nechuta, Robert Hodgson

Bioorg Med Chem Lett· January 2012

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The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): comparison of efficacy and side effects across rodent species.
Sherry X Lu, Guy A Higgins, Robert A Hodgson, Lynn A Hyde, Robert A Del Vecchio, Ginny D Ho

Eur J Pharmacol· July 2011

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Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models.
Robbie L McLeod, Deen B Tulshian, Donald C Bolser, Geoffrey B Varty, Marco Baptista, Ginny D Ho

Eur J Pharmacol· March 2010

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Effect of a novel NOP receptor agonist (SCH 225288) on guinea pig irritant-evoked, feline mechanically induced and canine infectious tracheobronchitis cough.
Robbie L McLeod, Deen B Tulshian, Ginny D Ho, Xiomara Fernandez, Donald C Bolser, Hongtao Zhang

Pharmacology· December 2009

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The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety.
Ginny D Ho, John Anthes, Ana Bercovici, John P Caldwell, Kuo-Chi Cheng, Hongtao Zhang

Bioorg Med Chem Lett· May 2009

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The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).
Geoffrey B Varty, Sherry X Lu, Cynthia A Morgan, Mary E Cohen-Williams, Robert A Hodgson, Hongtao Zhang, Ginny D Ho

J Pharmacol Exp Ther· August 2008

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Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 2.
Ginny D Ho, Ana Bercovici, Deen Tulshian, William J Greenlee, Ahmad Fawzi, Hongtao Zhang

Bioorg Med Chem Lett· June 2007

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Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.
Ginny D Ho, Ana Bercovici, Deen Tulshian, William J Greenlee, Ahmad Fawzi, Hongtao Zhang

Bioorg Med Chem Lett· June 2007

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