Publications by authors named "Giovanna Musco"

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Intrinsic disorder and fuzzy interactions drive multiple functions of HMGB1.
Michela Ghitti, Liam Sean Colley, Malisa Vittoria Mantonico, Giovanna Musco, Marco Emilio Bianchi

Trends Biochem Sci· October 2025

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Targeting the Liver Serine Protease TMPRSS6 Ameliorates Steatosis and Attenuates Fibrosis in Experimental MASLD.
Mariateresa Pettinato, Valeria Furiosi, Rossana Carleo, Letizia Bavuso Volpe, Shuling Guo, Giovanna Musco

Liver Int· July 2025

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Therapeutic targeting of cellular prion protein: toward the development of dual mechanism anti-prion compounds.
Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giovanna Musco, Roberto Chiesa

Neural Regen Res· April 2025

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SP140 represses specific loci by recruiting polycomb repressive complex 2 and NuRD complex.
Simone Tamburri, Chiara Zucchelli, Vittoria Matafora, Ettore Zapparoli, Zivojin Jevtic, Giovanna Musco

Nucleic Acids Res· February 2025

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The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma.
Andrea Berardi, Charlotte Leonie Kaestner, Michela Ghitti, Giacomo Quilici, Paolo Cocomazzi, Giovanna Musco

Nucleic Acids Res· January 2025

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Tau oligomers impair memory and synaptic plasticity through the cellular prion protein.
Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Giovanna Musco

Acta Neuropathol Commun· January 2025

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HMGB1, an evolving pleiotropic protein critical for cellular and tissue homeostasis: Role in aging and age-related diseases.
Elena Ruggieri, Erika Di Domenico, Andrea Giacomo Locatelli, Flavio Isopo, Sarah Damanti, Giovanna Musco

Ageing Res Rev· December 2024

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Lipid dysmetabolism in ceruloplasmin-deficient mice revealed both in vivo and ex vivo by MRI, MRS and NMR analyses.
Valeria Mannella, Linda Chaabane, Tamara Canu, Alan Zanardi, Sara Raia, Giovanna Musco

FEBS Open Bio· February 2024

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The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12.
Malisa Vittoria Mantonico, Federica De Leo, Giacomo Quilici, Liam Sean Colley, Francesco De Marchis, Giovanna Musco

Nat Commun· February 2024

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A novel aminopeptidase N/CD13 inhibitor selectively targets an endothelial form of CD13 after coupling to proteins.
Giulia Anderluzzi, Michela Ghitti, Anna Maria Gasparri, Giulia Taiè, Angelina Sacchi, Giovanna Musco

Cell Mol Life Sci· January 2024

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Erratum: A tetracationic porphyrin with dual anti-prion activity.
Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Eraña, Giovanna Musco

iScience· November 2023

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A tetracationic porphyrin with dual anti-prion activity.
Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Eraña, Giovanna Musco

iScience· September 2023

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A simple and robust nanosystem for photoacoustic imaging of bladder cancer based on α5β1-targeted gold nanorods.
Massimo Alfano, Elisa Alchera, Angelina Sacchi, Alessandro Gori, Giacomo Quilici, Giovanna Musco

J Nanobiotechnology· August 2023

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Nizp1 is a specific NUP98-NSD1 functional interactor that regulates NUP98-NSD1-dependent oncogenic programs.
Andrea Berardi, Oronza A Botrugno, Giacomo Quilici, José Manuel Garcia Manteiga, Angela Bachi, Giovanna Musco

FEBS J· April 2023

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Primary cilia sense glutamine availability and respond via asparagine synthetase.
Maria Elena Steidl, Elisa A Nigro, Anne Kallehauge Nielsen, Roberto Pagliarini, Laura Cassina, Giovanna Musco

Nat Metab· March 2023

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Pamoic acid is an inhibitor of HMGB1·CXCL12 elicited chemotaxis and reduces inflammation in murine models of Pseudomonas aeruginosa pneumonia.
Federica De Leo, Alice Rossi, Francesco De Marchis, Cristina Cigana, Medede Melessike, Giovanna Musco

Mol Med· September 2022

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Solution Structure of the BPSL1445 Protein of Reveals the SYLF Domain Three-Dimensional Fold.
Giacomo Quilici, Andrea Berardi, Chantal Fabris, Michela Ghitti, Marco Punta, Giovanna Musco

ACS Chem Biol· January 2022

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SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation.
Zivojin Jevtic, Vittoria Matafora, Francesca Casagrande, Fabio Santoro, Saverio Minucci, Giovanna Musco

J Exp Clin Cancer Res· January 2022

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Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand.
Stefano Tomassi, Vincenzo Maria D'Amore, Francesco Saverio Di Leva, Andrea Vannini, Giacomo Quilici, Giovanna Musco

J Med Chem· May 2021

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small molecules targeting the finger-finger interaction between the histone lysine methyltransferase NSD1 and Nizp1 repressor.
Andrea Berardi, Michela Ghitti, Giacomo Quilici, Giovanna Musco

Comput Struct Biotechnol J· December 2020

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Discovery of 5,5'-Methylenedi-2,3-Cresotic Acid as a Potent Inhibitor of the Chemotactic Activity of the HMGB1·CXCL12 Heterocomplex Using Virtual Screening and NMR Validation.
Federica De Leo, Giacomo Quilici, Francesco De Marchis, Malisa Vittoria Mantonico, Marco Emilio Bianchi, Giovanna Musco

Front Chem· November 2020

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Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity.
Alexander Chernorudskiy, Ersilia Varone, Sara Francesca Colombo, Stefano Fumagalli, Alfredo Cagnotto, Giovanna Musco

Proc Natl Acad Sci U S A· September 2020

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A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8.
Francesca Nardelli, Michela Ghitti, Giacomo Quilici, Alessandro Gori, Qingqiong Luo, Giovanna Musco

Chem Commun (Camb)· December 2019

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Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment.
Federica De Leo, Giacomo Quilici, Mario Tirone, Francesco De Marchis, Valeria Mannella, Giovanna Musco

EMBO Rep· October 2019

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Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling.
Barbara Valentinis, Simona Porcellini, Claudia Asperti, Manuela Cota, Dan Zhou, Giovanna Musco

Int J Mol Sci· September 2019

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