Publications by authors named "Giulia Canevari"

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Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors.
Giovanni Cervi, Roberto D'Alessio, Simona Bindi, Laura Buffa, Alessia Burocchi, Giulia Canevari

Eur J Med Chem· April 2024

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Correction to Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
Maria Menichincheri, Elena Ardini, Paola Magnaghi, Nilla Avanzi, Patrizia Banfi, Giulia Canevari

J Med Chem· September 2019

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The target landscape of clinical kinase drugs.
Susan Klaeger, Stephanie Heinzlmeir, Mathias Wilhelm, Harald Polzer, Binje Vick, Giulia Canevari

Science· December 2017

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Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
Maria Menichincheri, Elena Ardini, Paola Magnaghi, Nilla Avanzi, Patrizia Banfi, Giulia Canevari

J Med Chem· April 2016

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Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders.
Maria Gabriella Brasca, Paola Gnocchi, Marcella Nesi, Nadia Amboldi, Nilla Avanzi, Giulia Canevari

Bioorg Med Chem· May 2015

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Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors.
Maria Gabriella Brasca, Marcella Nesi, Nilla Avanzi, Dario Ballinari, Tiziano Bandiera, Giulia Canevari

Bioorg Med Chem· September 2014

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Structural insight into maternal embryonic leucine zipper kinase (MELK) conformation and inhibition toward structure-based drug design.
Giulia Canevari, Stefania Re Depaolini, Ulisse Cucchi, Jay A Bertrand, Elena Casale

Biochemistry· September 2013

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FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation.
Mario Milani, Francesco Ciriello, Sara Baroni, Vittorio Pandini, Giulia Canevari

J Mol Biol· August 2011

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Recognition of Smac-mimetic compounds by the BIR domain of cIAP1.
Federica Cossu, Francesca Malvezzi, Giulia Canevari, Eloise Mastrangelo, Daniele Lecis

Protein Sci· December 2010

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Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis.
Danila Crobu, Giulia Canevari, Mario Milani, Vittorio Pandini, Maria Antonietta Vanoni

Biochemistry· October 2009

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Structural basis for bivalent Smac-mimetics recognition in the IAP protein family.
Federica Cossu, Mario Milani, Eloise Mastrangelo, Patrice Vachette, Federica Servida, Giulia Canevari

J Mol Biol· September 2009

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