Publications by authors named "Gordon Gibson"

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Asenapine pharmacokinetics in hepatic and renal impairment.
Pierre Peeters, Howard Bockbrader, Edwin Spaans, Peter Dogterom, Kenneth Lasseter, Gordon L Gibson

Clin Pharmacokinet· July 2011

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A PXR-mediated negative feedback loop attenuates the expression of CYP3A in response to the PXR agonist pregnenalone-16α-carbonitrile.
Ian Bailey, G Gordon Gibson, Kathryn Plant, Mark Graham, Nick Plant

PLoS One· February 2011

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Effect of renal impairment on the pharmacokinetics of PD 0200390, a novel ligand for the voltage-gated calcium channel alpha-2-delta subunit.
Brian Corrigan, Douglas E Feltner, Daniele Ouellet, John L Werth, Allen E Moton, Gordon Gibson

Br J Clin Pharmacol· August 2009

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In silico and in vitro modeling of hepatocyte drug transport processes: importance of ABCC2 expression levels in the disposition of carboxydichlorofluroscein.
Katharine Howe, G Gordon Gibson, Tanya Coleman, Nick Plant

Drug Metab Dispos· February 2009

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The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1.
Kathryn E Plant, Elizabeth Anderson, Nicole Simecek, Richard Brown, Sam Forster, G Gordon Gibson

Toxicol Appl Pharmacol· February 2009

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Modelling and simulation in prediction of human xenobiotic absorption, distribution, metabolism and excretion (ADME): in vitro-in vivo extrapolations (IVIVE).
G Gordon Gibson, Amin Rostami-Hodjegan

Xenobiotica· January 2008

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The absorption, distribution, metabolism and excretion (ADME) transcriptome.
Gordon Gibson, Roger Ulrich, Greg Slatter

Xenobiotica· January 2007

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Transcriptomic and phylogenetic analysis of Kpna genes: a family of nuclear import factors modulated in xenobiotic-mediated liver growth.
Kathryn E Plant, David M Everett, G Gordon Gibson, Jon Lyon, Nick J Plant

Pharmacogenet Genomics· September 2006

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Transcriptional regulation of the human pregnane-X receptor.
G Gordon Gibson, Anna Phillips, Sihem Aouabdi, Kate Plant, Nick Plant

Drug Metab Rev· June 2006

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Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor alpha binding site within the proximal promoter of PXR.
Sihem Aouabdi, Gordon Gibson, Nick Plant

Drug Metab Dispos· January 2006

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Effect of rosuvastatin on warfarin pharmacodynamics and pharmacokinetics.
Steven G Simonson, Paul D Martin, Patrick D Mitchell, Kenneth Lasseter, Gordon Gibson

J Clin Pharmacol· August 2005

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Impact of transcription factor profile and chromatin conformation on human hepatocyte CYP3A gene expression.
Anna Phillips, Steve R Hood, G Gordon Gibson, Nick J Plant

Drug Metab Dispos· February 2005

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Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.
Jasminder Sahi, Ralph H Stern, Mark A Milad, Kelly A Rose, Gordon Gibson

Drug Metab Dispos· December 2004

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Role of Sp1, C/EBP alpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene.
Vincent Bombail, Kevin Taylor, G Gordon Gibson, Nick Plant

Drug Metab Dispos· May 2004

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Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression.
Roger G Ulrich, John C Rockett, G Gordon Gibson, Syril D Pettit

Environ Health Perspect· March 2004

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Gene expression changes in rat liver following exposure to liver growth agents: role of Kupffer cells in xenobiotic-mediated liver growth.
Sarah E Crunkhorn, Kathryn E Plant, Gordon G Gibson, Kerstin Kramer, Jon Lyon

Biochem Pharmacol· January 2004

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Lansoprazole increases testosterone metabolism and clearance in male Sprague-Dawley rats: implications for Leydig cell carcinogenesis.
Michelle Coulson, G Gordon Gibson, Nick Plant, Tim Hammond, Mark Graham

Toxicol Appl Pharmacol· October 2003

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Evaluation of the toxicological relevance of CYP3A4 induction.
Nick J Plant, G Gordon Gibson

Curr Opin Drug Discov Devel· January 2003

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Receptor-dependent regulation of the CYP3A4 gene.
G Gordon Gibson, Wafaa el-Sankary, Nick J Plant

Toxicology· December 2002

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Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
Wafaa El-Sankary, Vincent Bombail, G Gordon Gibson, Nick Plant

Drug Metab Dispos· September 2002

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Efficacy of levetiracetam in developmentally disabled patients: a review of the literature and six case reports.
Gordon Gibson

Epilepsy Behav· June 2002

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