Publications by authors named "Howard Bockbrader"

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Population pharmacokinetic and pharmacokinetic-pharmacodynamic modeling of bempedoic acid and low-density lipoprotein cholesterol in healthy subjects and patients with dyslipidemia.
Satyawan B Jadhav, Benny M Amore, Howard Bockbrader, Ryan L Crass, Sunny Chapel

J Pharmacokinet Pharmacodyn· October 2023

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Development of a Population Pharmacokinetic Model for the Diroximel Fumarate Metabolites Monomethyl Fumarate and 2-Hydroxyethyl Succinimide Following Oral Administration of Diroximel Fumarate in Healthy Participants and Patients with Multiple Sclerosis.
Mita Kuchimanchi, Howard Bockbrader, Nancy Dolphin, Daniel Epling, Lauren Quinlan

Neurol Ther· March 2022

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Population Pharmacokinetics of Vixotrigine in Healthy Volunteers and Subjects with Trigeminal Neuralgia, Painful Lumbosacral Radiculopathy and Erythromelalgia.
Himanshu Naik, Yuan Zhao, Fiona Forrestal, Simon Cleall, Howard Bockbrader

Eur J Drug Metab Pharmacokinet· May 2021

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Population Pharmacokinetics of Pregabalin Extended-Release in Healthy Volunteers and Patients With Postherpetic Neuralgia, Fibromyalgia, and Partial-Onset Seizures.
Marci Chew, Guangli Ma, Rujia Xie, Howard Bockbrader, Sunny Chapel

J Clin Pharmacol· November 2019

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Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial.
Marci L Chew, Anna Plotka, Christine W Alvey, Verne W Pitman, Tanja Alebic-Kolbah, Howard N Bockbrader

Clin Drug Investig· May 2015

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Safety, tolerability, and pharmacokinetics of pregabalin in children with refractory partial seizures: a phase 1, randomized controlled study.
Donald Mann, Jing Liu, Marci L Chew, Howard Bockbrader, Christine W Alvey

Epilepsia· December 2014

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Pharmacokinetics of pregabalin controlled-release in healthy volunteers: effect of food in five single-dose, randomized, clinical pharmacology studies.
Marci L Chew, Anna Plotka, Christine W Alvey, Verne W Pitman, Tanja Alebic-Kolbah, Howard N Bockbrader

Clin Drug Investig· September 2014

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Pregabalin controlled-release pharmacokinetics in healthy volunteers: analysis of four multiple-dose randomized clinical pharmacology studies.
Marci L Chew, Christine W Alvey, Anna Plotka, Verne W Pitman, Tanja Alebic-Kolbah, Howard N Bockbrader

Clin Drug Investig· September 2014

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Bioequivalence assessment of a pregabalin capsule and oral solution in fasted healthy volunteers: a randomized, crossover study.
Howard N Bockbrader, Christine W Alvey, Brian W Corrigan, Louis L Radulovic

Int J Clin Pharmacol Ther· March 2013

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Gabapentin to pregabalin therapy transition: a pharmacokinetic simulation.
Howard N Bockbrader, Meeta N Budhwani, David L Wesche

Am J Ther· January 2013

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Population pharmacokinetics of pregabalin in healthy subjects and patients with post-herpetic neuralgia or diabetic peripheral neuropathy.
Satoshi Shoji, Misaki Suzuki, Yoshiro Tomono, Howard N Bockbrader, Shigeyuki Matsui

Br J Clin Pharmacol· July 2011

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Asenapine pharmacokinetics in hepatic and renal impairment.
Pierre Peeters, Howard Bockbrader, Edwin Spaans, Peter Dogterom, Kenneth Lasseter

Clin Pharmacokinet· July 2011

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Population pharmacokinetics of pregabalin in healthy subjects and patients with chronic pain or partial seizures.
Howard N Bockbrader, Paula Burger, Lloyd Knapp, Brian W Corrigan

Epilepsia· February 2011

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Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine.
Howard N Bockbrader, Paula Burger, Lloyd Knapp

Epilepsia· February 2011

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A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin.
Howard N Bockbrader, David Wesche, Raymond Miller, Sunny Chapel, Nancy Janiczek

Clin Pharmacokinet· October 2010

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Clinical pharmacokinetics of pregabalin in healthy volunteers.
Howard N Bockbrader, Louis L Radulovic, Edward L Posvar, James C Strand, Christine W Alvey

J Clin Pharmacol· August 2010

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Exposure-response analysis in patients with schizophrenia to assess the effect of asenapine on QTc prolongation.
Sunny Chapel, Matt M Hutmacher, George Haig, Howard Bockbrader, Rik de Greef

J Clin Pharmacol· November 2009

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Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy.
Martin J Brodie, Elaine A Wilson, David L Wesche, Christine W Alvey, Edward J Randinitis, Howard N Bockbrader

Epilepsia· September 2005

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Relief of painful diabetic peripheral neuropathy with pregabalin: a randomized, placebo-controlled trial.
Ralph W Richter, Russell Portenoy, Uma Sharma, Linda Lamoreaux, Howard Bockbrader

J Pain· April 2005

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Exposure-response analysis of pregabalin add-on treatment of patients with refractory partial seizures.
Raymond Miller, Bill Frame, Brian Corrigan, Paula Burger, Howard Bockbrader

Clin Pharmacol Ther· June 2003

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Pharmacokinetics of pregabalin in subjects with various degrees of renal function.
Edward J Randinitis, Edward L Posvar, Christine W Alvey, Allen J Sedman, Jack A Cook, Howard N Bockbrader

J Clin Pharmacol· March 2003

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