Publications by authors named "Hanspeter Nick"

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Identification of cardiac glycoside molecules as inhibitors of c-Myc IRES-mediated translation.
Marie-Cecile Didiot, Jeffrey Hewett, Thibault Varin, Felix Freuler, Douglas Selinger, Hanspeter Nick

J Biomol Screen· April 2013

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Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats.
Casey Brewer, Maya Otto-Duessel, Jens Lykkesfeldt, Hanspeter Nick, John C Wood

Exp Hematol· October 2012

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Ability of deferasirox to bind iron during measurement of iron.
Massin Lebitasy, Els Ampe, Jean-Daniel Hecq, Linda Karmani, Hanspeter Nick

Clin Chem Lab Med· March 2010

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Reduction in labile plasma iron during treatment with deferasirox, a once-daily oral iron chelator, in heavily iron-overloaded patients with beta-thalassaemia.
Shahina Daar, Anil Pathare, Hanspeter Nick, Ulrike Kriemler-Krahn, Abdel Hmissi

Eur J Haematol· June 2009

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Deferasirox reduces iron overload in a murine model of juvenile hemochromatosis.
Hanspeter Nick, Peter R Allegrini, Lucy Fozard, Ursula Junker, Lisa Rojkjaer

Exp Biol Med (Maywood)· May 2009

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Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats.
Gerard J M Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick

Drug Metab Dispos· December 2008

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Safety and efficacy of combined chelation therapy with deferasirox and deferoxamine in a gerbil model of iron overload.
Maya Otto-Duessel, Casey Brewer, Ignacio Gonzalez, Hanspeter Nick, John C Wood

Acta Haematol· December 2008

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Influence of iron chelation on R1 and R2 calibration curves in gerbil liver and heart.
John C Wood, Michelle Aguilar, Maya Otto-Duessel, Hanspeter Nick, Marvin D Nelson

Magn Reson Med· July 2008

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Iron chelation, quo vadis?
Hanspeter Nick

Curr Opin Chem Biol· August 2007

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Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy.
Maya Otto-Duessel, Michelle Aguilar, Hanspeter Nick, Rex Moats, John C Wood

Exp Hematol· July 2007

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Action of chelators in iron-loaded cardiac cells: Accessibility to intracellular labile iron and functional consequences.
Hava Glickstein, Rinat Ben El, Gabi Link, William Breuer, Abraham M Konijn, Hanspeter Nick

Blood· November 2006

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Deferasirox and deferiprone remove cardiac iron in the iron-overloaded gerbil.
John C Wood, Maya Otto-Duessel, Ignacio Gonzalez, Michelle I Aguilar, Hiro Shimada, Hanspeter Nick

Transl Res· November 2006

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The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox.
Karine Chantrel-Groussard, François Gaboriau, Nicole Pasdeloup, René Havouis, Hanspeter Nick

Eur J Pharmacol· July 2006

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Cardiac iron determines cardiac T2*, T2, and T1 in the gerbil model of iron cardiomyopathy.
John C Wood, Maya Otto-Duessel, Michelle Aguilar, Hanspeter Nick, Marvin D Nelson

Circulation· July 2005

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Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists.
Heinrich Rueeger, Marc Gerspacher, Peter Buehlmayer, Pascal Rigollier, Yasuchika Yamaguchi, Hanspeter Nick

Bioorg Med Chem Lett· May 2004

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ICL670A: preclinical profile.
Hanspeter Nick, Agnes Wong, Pierre Acklin, Bernard Faller, Yi Jin

Adv Exp Med Biol· July 2003

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Development of tridentate iron chelators: from desferrithiocin to ICL670.
Hanspeter Nick, Pierre Acklin, René Lattmann, Peter Buehlmayer, Suzanne Hauffe

Curr Med Chem· June 2003

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