Publications by authors named "Heather Handl"

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Use of PD-1 and PD-L1 inhibitors after first-line therapy in esophageal cancer patients in the US.
Jason C Allaire, Mark Balk, Soraya Azmi, Heather L Handl, Keri Yang

Curr Med Res Opin· August 2021

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Cell-specific targeting by heterobivalent ligands.
Jatinder S Josan, Heather L Handl, Rajesh Sankaranarayanan, Liping Xu, Ronald M Lynch

Bioconjug Chem· July 2011

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Heterobivalent ligands crosslink multiple cell-surface receptors--a step towards personal medicine.
Jatinder S Josan, Rajesh Sankaranarayanan, Heather L Handl, Steve Fernandes, Liping Xu

Adv Exp Med Biol· June 2009

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Solid-Phase Synthesis of Heterobivalent Ligands Targeted to Melanocortin and Cholecystokinin Receptors.
Jatinder S Josan, Josef Vagner, Heather L Handl, Rajesh Sankaranarayanan, Robert J Gillies

Int J Pept Res Ther· December 2008

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Heterobivalent ligands crosslink multiple cell-surface receptors: the human melanocortin-4 and delta-opioid receptors.
Josef Vagner, Liping Xu, Heather L Handl, Jatinder S Josan, David L Morse

Angew Chem Int Ed Engl· March 2008

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Synthesis and evaluation of bivalent NDP-alpha-MSH(7) peptide ligands for binding to the human melanocortin receptor 4 (hMC4R).
Heather L Handl, Rajesh Sankaranarayanan, Jatinder S Josan, Josef Vagner, Eugene A Mash

Bioconjug Chem· October 2007

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Immunobiological aspects of therapeutic antibodies and related characterization approaches.
Patrick Mengyuan Liu, Heather Handl, Linglong Zou, Brian Kim

Curr Opin Drug Discov Devel· September 2007

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Rigid linkers for bioactive peptides.
Josef Vagner, Heather L Handl, Yasunari Monguchi, Umasish Jana, Lucinda J Begay

Bioconjug Chem· January 2007

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Development of a lanthanide-based assay for detection of receptor-ligand interactions at the delta-opioid receptor.
Heather L Handl, Josef Vagner, Henry I Yamamura, Victor J Hruby, Robert J Gillies

Anal Biochem· August 2005

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Sequence specific recognition of DNA by tailor-made hairpin conjugates of achiral seco-cyclopropaneindoline-2-benzofurancarboxamide and pyrrole-imidazole polyamides.
Carly A Price, Brian M Lingerfelt, Heather L Handl, Konstantinos Kiakos, John A Hartley

Bioorg Med Chem Lett· June 2005

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Lanthanide-based luminescent assays for ligand-receptor interactions.
Heather L Handl, Robert J Gillies

Life Sci· June 2005

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Design, synthesis, and biological evaluation of achiral analogs of duocarmycin SA.
Kristen Daniell, Michelle Stewart, Erik Madsen, Minh Le, Heather Handl

Bioorg Med Chem Lett· January 2005

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A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
Stanley Kupchinsky, Sara Centioni, Tiffany Howard, John Trzupek, Shane Roller, Heather Handl

Bioorg Med Chem· December 2004

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Hitting multiple targets with multimeric ligands.
Heather L Handl, Josef Vagner, Haiyong Han, Eugene Mash, Victor J Hruby

Expert Opin Ther Targets· December 2004

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Lanthanide-based time-resolved fluorescence of in cyto ligand-receptor interactions.
Heather L Handl, Josef Vagner, Henry I Yamamura, Victor J Hruby, Robert J Gillies

Anal Biochem· July 2004

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Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: homooligomers of alpha-MSH.
Josef Vagner, Heather L Handl, Robert J Gillies, Victor J Hruby

Bioorg Med Chem Lett· January 2004

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Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues.
Tiffany T Howard, Brian M Lingerfelt, Bethany L Purnell, Adrienne E Scott, Carly A Price, Heather L Handl

Bioorg Med Chem· September 2002

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Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides.
James L Toth, Carly A Price, Erik C Madsen, Heather L Handl, Stephen J Hudson

Bioorg Med Chem Lett· August 2002

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