Publications by authors named "Heather Wescott"

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Profile of NT-0527, a brain penetrant NLRP3 Inflammasome inhibitor suitable as an tool compound for neuroinflammatory disorders.
David Harrison, Andy Billinton, Mark G Bock, Nicholas P Clarke, Zsofia Digby, Heather Wescott

RSC Med Chem· September 2025

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Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1-pyrazol-4-yl)({[(2)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework.
John R Doedens, Pamela Smolak, MyTrang Nguyen, Heather Wescott, Christine Diamond

ACS Pharmacol Transl Sci· May 2024

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Target Cell Activation of a Structurally Novel NOD-Like Receptor Pyrin Domain-Containing Protein 3 Inhibitor NT-0796 Enhances Potency.
Pamela Smolak, MyTrang Nguyen, Christine Diamond, Heather Wescott, John R Doedens

J Pharmacol Exp Ther· February 2024

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Anthranilic amide and imidazobenzothiadiazole compounds disrupt membrane potential.
Jake Smith, Heather Wescott, Julie Early, Steven Mullen, Junitta Guzman

Medchemcomm· June 2019

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Identification of Enolase as the Target of 2-Aminothiazoles in .
Heather H Wescott, Edison S Zuniga, Anumita Bajpai, Carolina Trujillo, Sabine Ehrt

Front Microbiol· October 2018

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Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.
Laura A T Cleghorn, Peter C Ray, Joshua Odingo, Anuradha Kumar, Heather Wescott

J Med Chem· August 2018

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Imidazopyridine Compounds Inhibit Mycobacterial Growth by Depleting ATP Levels.
Theresa O'Malley, Torey Alling, Julie V Early, Heather A Wescott, Anuradha Kumar

Antimicrob Agents Chemother· June 2018

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