Publications by authors named "Helen Lenthall"

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Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies.
Ohan Mazigi, David B Langley, Jake Y Henry, Deborah L Burnett, Meghna Sobti, Helen Lenthall

Proc Natl Acad Sci U S A· January 2025

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Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.
Tina Nguyen, Anthony Lau, Julia Bier, Kristen C Cooke, Helen Lenthall

J Exp Med· June 2023

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Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau, Helen Lenthall

Sci Adv· April 2023

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Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Romain Rouet, Jake Y Henry, Matt D Johansen, Meghna Sobti, Harikrishnan Balachandran, Helen Lenthall

Nat Commun· February 2023

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Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia.
Anupriya Aggarwal, Alberto Ospina Stella, Gregory Walker, Anouschka Akerman, Camille Esneau, Helen Lenthall

Nat Microbiol· June 2022

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Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Deborah L Burnett, Katherine J L Jackson, David B Langley, Anupria Aggrawal, Alberto Ospina Stella, Helen Lenthall

Immunity· December 2021

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Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Romain Rouet, Ohan Mazigi, Gregory J Walker, David B Langley, Meghna Sobti, Helen Lenthall

MAbs· May 2021

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Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.
Anthony Lau, Danielle T Avery, Katherine Jackson, Helen Lenthall, Stefano Volpi

J Exp Med· February 2020

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Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4 T cells.
Julia Bier, Geetha Rao, Kathryn Payne, Henry Brigden, Elise French, Helen Lenthall

J Allergy Clin Immunol· July 2019

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B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects.
Imogen Moran, Danielle T Avery, Kathryn Payne, Helen Lenthall, E Graham Davies

J Allergy Clin Immunol· June 2019

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Germline-activating mutations in compromise B cell development and function.
Danielle T Avery, Alisa Kane, Tina Nguyen, Anthony Lau, Akira Nguyen, Helen Lenthall

J Exp Med· August 2018

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Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome.
Simon J Pelham, Helen C Lenthall, Elissa K Deenick, Stuart G Tangye

J Allergy Clin Immunol· October 2016

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