Publications by authors named "Sean C Warren"

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Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Sean C Warren

Sci Adv· July 2024

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Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau

Sci Adv· April 2023

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Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status.
Kendelle J Murphy, Daniel A Reed, Claire Vennin, James R W Conway, Max Nobis, Sean C Warren

Sci Adv· October 2021

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Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Alessia Floerchinger, Kendelle J Murphy, Sharissa L Latham, Sean C Warren, Andrew T McCulloch

Cell Rep· September 2021

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Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis.
Monisha Samuel, Pamali Fonseka, Rahul Sanwlani, Lahiru Gangoda, Sing Ho Chee, Sean C Warren

Nat Commun· June 2021

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Shedding new light on RhoA signalling as a drug target using a novel RhoA-FRET biosensor mouse.
Max Nobis, David Herrmann, Sean C Warren, Douglas Strathdee, Thomas R Cox

Small GTPases· July 2020

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MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer.
Arcadi Cipponi, David L Goode, Justin Bedo, Mark J McCabe, Marina Pajic, Sean C Warren

Science· June 2020

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Fluids and their mechanics in tumour transit: shaping metastasis.
Gautier Follain, David Herrmann, Sébastien Harlepp, Vincent Hyenne, Naël Osmani, Sean C Warren

Nat Rev Cancer· February 2020

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CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan.
Claire Vennin, Pauline Mélénec, Romain Rouet, Max Nobis, Aurélie S Cazet, Sean C Warren

Nat Commun· August 2019

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Removing physiological motion from intravital and clinical functional imaging data.
Sean C Warren, Max Nobis, Astrid Magenau, Yousuf H Mohammed, David Herrmann

Elife· July 2018

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Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.
James R W Conway, Sean C Warren, David Herrmann, Kendelle J Murphy, Aurélie S Cazet

Cell Rep· June 2018

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Molecular mobility and activity in an intravital imaging setting - implications for cancer progression and targeting.
Max Nobis, Sean C Warren, Morghan C Lucas, Kendelle J Murphy, David Herrmann

J Cell Sci· March 2018

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In vivo multiphoton microscopy using a handheld scanner with lateral and axial motion compensation.
Ben Sherlock, Sean C Warren, Yuriy Alexandrov, Fei Yu, James Stone

J Biophotonics· February 2018

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Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.
James R W Conway, Claire Vennin, Aurélie S Cazet, David Herrmann, Kendelle J Murphy, Sean C Warren

Sci Rep· December 2017

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A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.
Max Nobis, David Herrmann, Sean C Warren, Shereen Kadir, Wilfred Leung

Cell Rep· October 2017

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Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors.
James R W Conway, Sean C Warren, Paul Timpson

Methods· September 2017

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Recruitment Kinetics of Tropomyosin Tpm3.1 to Actin Filament Bundles in the Cytoskeleton Is Independent of Actin Filament Kinetics.
Mark A Appaduray, Andrius Masedunskas, Nicole S Bryce, Christine A Lucas, Sean C Warren

PLoS One· July 2017

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Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.
Claire Vennin, Venessa T Chin, Sean C Warren, Morghan C Lucas, David Herrmann

Sci Transl Med· April 2017

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Open Source High Content Analysis Utilizing Automated Fluorescence Lifetime Imaging Microscopy.
Frederik Görlitz, Douglas J Kelly, Sean C Warren, Dominic Alibhai, Lucien West

J Vis Exp· January 2017

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Corrigendum: Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).
Anca Margineanu, Jia Jia Chan, Douglas J Kelly, Sean C Warren, Delphine Flatters

Sci Rep· September 2016

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Adaptive multiphoton endomicroscopy through a dynamically deformed multicore optical fiber using proximal detection.
Sean C Warren, Youngchan Kim, James M Stone, Claire Mitchell, Jonathan C Knight

Opt Express· September 2016

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Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM.
George Chennell, Robin J W Willows, Sean C Warren, David Carling, Paul M W French

Sensors (Basel)· August 2016

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Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).
Anca Margineanu, Jia Jia Chan, Douglas J Kelly, Sean C Warren, Delphine Flatters

Sci Rep· June 2016

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Visualising apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time.
Natalie Andrews, Marie-Christine Ramel, Sunil Kumar, Yuriy Alexandrov, Douglas J Kelly, Sean C Warren

J Biophotonics· April 2016

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Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue.
Zahra Erami, David Herrmann, Sean C Warren, Max Nobis, Ewan J McGhee

Cell Rep· January 2016

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