Publications by authors named "Helen Maddock"

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Doxorubicin increases G-protein coupled receptor-mediated vasoconstriction in coronary arteries via the mitogen-activated protein kinase kinase 1/2 pathway.
Caroline Lozahic, Helen Maddock, Mark Wheatley, Hardip Sandhu

Eur J Pharmacol· November 2025

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COVID-19 is associated with cardiac structural and functional remodelling in healthy middle-aged and older individuals.
Mushidur Rahman, Sophie L Russell, Nduka C Okwose, Gordon McGregor, Helen Maddock

Clin Physiol Funct Imaging· January 2025

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Relationship between heart rate variability and echocardiography indices of cardiac function in healthy individuals.
Mushidur Rahman, Sophie L Russell, Nduka C Okwose, Charles J Steward, Helen Maddock

Clin Physiol Funct Imaging· January 2025

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Doxorubicin alters G-protein coupled receptor-mediated vasocontraction in rat coronary arteries.
Caroline Lozahic, Helen Maddock, Mark Wheatley, Hardip Sandhu

Naunyn Schmiedebergs Arch Pharmacol· August 2024

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Exploring Changes in Myocyte Structure, Contractility, and Energetics From Mechanical Unloading in Patients With Heart Failure Undergoing Ventricular Assist Device Implantation: A Systematic Review and Meta-Analysis.
Patrick Tran, Clement Lau, Mithilesh Joshi, Michael Kuehl, Helen Maddock

Heart Lung Circ· August 2024

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Profiling the Biomechanical Responses to Workload on the Human Myocyte to Explore the Concept of Myocardial Fatigue and Reversibility: Rationale and Design of the POWER Heart Failure Study.
Patrick Tran, Adam Linekar, Uday Dandekar, Thomas Barker, Sendhil Balasubramanian, Helen Maddock

J Cardiovasc Transl Res· April 2024

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Development of a novel low-order model for atrial function and a study of atrial mechano-electric feedback.
Nicholas F Pearce, Mark C Turner, Helen L Maddock, Eun-Jin Kim

Comput Biol Med· June 2023

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Cardiovascular implications and physical activity in middle-aged and older adults with a history of COVID-19 (CV COVID): a protocol for a randomised controlled trial.
Mushidur Rahman, Sophie L Russell, Nduka C Okwose, Olivia M A Hood, Amy E Harwood, Helen Maddock

Trials· May 2023

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Validity and reliability of short-term heart-rate variability from disposable electrocardiography leads.
Nduka C Okwose, Sophie L Russell, Mushidur Rahman, Charles J Steward, Amy E Harwood, Helen Maddock

Health Sci Rep· January 2023

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Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK.
Refik Kuburas, Mayel Gharanei, Irmgard Haussmann, Helen Maddock, Hardip Sandhu

J Cardiovasc Pharmacol· June 2022

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Myocardial Fatigue: a Mechano-energetic Concept in Heart Failure.
Patrick Tran, Helen Maddock, Prithwish Banerjee

Curr Cardiol Rep· June 2022

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Cardiac stunning during haemodialysis: the therapeutic effect of intra-dialytic exercise.
Scott McGuire, Elizabeth J Horton, Derek Renshaw, Klaris Chan, Alfonso Jimenez, Helen Maddock

Clin Kidney J· May 2021

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Anti-cancer Therapy Leads to Increased Cardiovascular Susceptibility to COVID-19.
Caroline Lozahic, Helen Maddock, Hardip Sandhu

Front Cardiovasc Med· April 2021

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The cardiac work-loop technique: An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles.
Sophie Fletcher, Helen Maddock, Rob S James, Rob Wallis, Mayel Gharanei

Sci Rep· March 2020

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Ageing alters the severity of Sunitinib-induced cardiotoxicity: Investigating the mitogen activated kinase kinase 7 pathway association.
Samantha Cooper, Hardip Sandhu, Afthab Hussain, Christopher Mee, Helen Maddock

Toxicology· January 2019

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The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection-evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology.
Sean M Davidson, Sapna Arjun, Maryna V Basalay, Robert M Bell, Daniel I Bromage, Helen Maddock

Basic Res Cardiol· October 2018

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Involvement of mitogen activated kinase kinase 7 intracellular signalling pathway in Sunitinib-induced cardiotoxicity.
Samantha Louise Cooper, Hardip Sandhu, Afthab Hussain, Christopher Mee, Helen Maddock

Toxicology· February 2018

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Attenuation of Sunitinib-induced cardiotoxicity through the A3 adenosine receptor activation.
Hardip Sandhu, Samantha Cooper, Afthab Hussain, Christopher Mee, Helen Maddock

Eur J Pharmacol· November 2017

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Predictivity of in vitro non-clinical cardiac contractility assays for inotropic effects in humans--A literature search.
Rob Wallis, Mayel Gharanei, Helen Maddock

J Pharmacol Toxicol Methods· July 2016

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Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay.
Mayel Gharanei, Afthab Hussain, Rob S James, Omar Janneh, Helen Maddock

Toxicol In Vitro· August 2014

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Attenuation of doxorubicin-induced cardiotoxicity by mdivi-1: a mitochondrial division/mitophagy inhibitor.
Mayel Gharanei, Afthab Hussain, Omar Janneh, Helen Maddock

PLoS One· June 2014

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Ipratropium bromide-mediated myocardial injury in in vitro models of myocardial ischaemia/reperfusion.
Kate L Harvey, Afthab Hussain, Helen L Maddock

Toxicol Sci· April 2014

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Molecular basis of cancer-therapy-induced cardiotoxicity: introducing microRNA biomarkers for early assessment of subclinical myocardial injury.
Hardip Sandhu, Helen Maddock

Clin Sci (Lond)· March 2014

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Caspase inhibition via A3 adenosine receptors: a new cardioprotective mechanism against myocardial infarction.
Afthab Hussain, Ahmed Mayel Gharanei, Aarondeep Singh Nagra, Helen L Maddock

Cardiovasc Drugs Ther· February 2014

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Effects of hydrogen sulphide on the isolated perfused rat heart.
Afthab Hussain, Helen Maddock, Hajar Al-Rajaibi, Ray J Carson

Sultan Qaboos Univ Med J· May 2011

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