Publications by authors named "Mark Wheatley"

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Doxorubicin increases G-protein coupled receptor-mediated vasoconstriction in coronary arteries via the mitogen-activated protein kinase kinase 1/2 pathway.
Caroline Lozahic, Helen Maddock, Mark Wheatley, Hardip Sandhu

Eur J Pharmacol· November 2025

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Tunable Terpolymer Series for the Systematic Investigation of Membrane Proteins.
Gestél C Kuyler, Elaine Barnard, Pooja Sridhar, Rebecca J Murray, Naomi L Pollock, Mark Wheatley

Biomacromolecules· January 2025

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Doxorubicin alters G-protein coupled receptor-mediated vasocontraction in rat coronary arteries.
Caroline Lozahic, Helen Maddock, Mark Wheatley, Hardip Sandhu

Naunyn Schmiedebergs Arch Pharmacol· August 2024

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Long-Circulating Vasoactive 1,18-Octadecanedioic Acid-Terlipressin Conjugate.
Or Berger, Wonmin Choi, Caroline H Ko, Matthew P Thompson, Michael J Avram, Mark Wheatley

ACS Pharmacol Transl Sci· May 2024

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GPCRs in the round: SMA-like copolymers and SMALPs as a platform for investigating GPCRs.
Hoor Ayub, Rebecca J Murray, Gestél C Kuyler, Farhaan Napier-Khwaja, Joseph Gunner, Mark Wheatley

Arch Biochem Biophys· April 2024

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Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles.
Rachael L Grime, Richard T Logan, Stephanie A Nestorow, Pooja Sridhar, Patricia C Edwards, Mark Wheatley

Nanoscale· August 2021

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Ligand-induced conformational changes in a SMALP-encapsulated GPCR.
Sarah J Routledge, Mohammed Jamshad, Haydn A Little, Yu-Pin Lin, John Simms, Mark Wheatley

Biochim Biophys Acta Biomembr· June 2020

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Single molecule binding of a ligand to a G-protein-coupled receptor in real time using fluorescence correlation spectroscopy, rendered possible by nano-encapsulation in styrene maleic acid lipid particles.
Rachael L Grime, Joelle Goulding, Romez Uddin, Leigh A Stoddart, Stephen J Hill, Mark Wheatley

Nanoscale· June 2020

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Interactions between RAMP2 and CRF receptors: The effect of receptor subtypes, splice variants and cell context.
Sian Bailey, Matthew Harris, Kerry Barkan, Ian Winfield, Matthew Thomas Harper, Mark Wheatley

Biochim Biophys Acta Biomembr· May 2019

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An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles.
Stephen C L Hall, Cecilia Tognoloni, Jack Charlton, Éilís C Bragginton, Alice J Rothnie, Mark Wheatley

Nanoscale· June 2018

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GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential.
Mark Wheatley, Jack Charlton, Mohammed Jamshad, Sarah J Routledge, Sian Bailey

Biochem Soc Trans· April 2016

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Offload zones to mitigate emergency medical services (EMS) offload delay in the emergency department: a process map and hazard analysis.
Alix J E Carter, James B Gould, Peter Vanberkel, Jan L Jensen, Jolene Cook, Mark R Wheatley

CJEM· November 2015

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G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent.
Mohammed Jamshad, Jack Charlton, Yu-Pin Lin, Sarah J Routledge, Zharain Bawa, Mark Wheatley

Biosci Rep· April 2015

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Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins.
Mohammed Jamshad, Vinciane Grimard, Ilaria Idini, Tim J Knowles, Miriam R Dowle, Mark Wheatley

Nano Res· March 2015

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Picture of nurse with red nails sends wrong message on hygiene.
Mark Wheatley

Nurs Stand· April 2014

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G-protein-coupled receptors: from structural insights to functional mechanisms.
Bice Chini, Marco Parenti, David R Poyner, Mark Wheatley

Biochem Soc Trans· February 2013

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The activation of the CGRP receptor.
James Barwell, Mark Wheatley, Alex C Conner, Bruck Taddese, Shabana Vohra

Biochem Soc Trans· February 2013

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The role of the extracellular loops of the CGRP receptor, a family B GPCR.
James Barwell, Michael J Woolley, Mark Wheatley, Alex C Conner, David R Poyner

Biochem Soc Trans· April 2012

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The use of site-directed mutagenesis to study GPCRs.
Alex C Conner, James Barwell, David R Poyner, Mark Wheatley

Methods Mol Biol· September 2011

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Surfactant-free purification of membrane proteins with intact native membrane environment.
Mohammed Jamshad, Yu-Pin Lin, Timothy J Knowles, Rosemary A Parslow, Craig Harris, Mark Wheatley

Biochem Soc Trans· June 2011

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Agonist-specific requirement for a glutamate in transmembrane helix 1 of the oxytocin receptor.
Denise L Wootten, John Simms, Amelia J Massoura, Julie E Trim, Mark Wheatley

Mol Cell Endocrinol· February 2011

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Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease.
Julie Parkes, Paul Roderick, Scott Harris, Christopher Day, David Mutimer, Mark Wheatley

Gut· September 2010

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A novel thromboxane A2 receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis.
Andrew D Mumford, Ban B Dawood, Martina E Daly, Sherina L Murden, Michael D Williams, Mark Wheatley

Blood· January 2010

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Structure-function analysis of RAMP1-RAMP3 chimeras.
Tao Qi, John Simms, Richard J Bailey, Mark Wheatley, Dan L Rathbone

Biochemistry· January 2010

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Targeting V1A-vasopressin receptors with [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) identifies a strategy to develop novel anti-cancer therapies.
Alison C MacKinnon, Uzma Tufail-Hanif, Mark Wheatley, Adriano G Rossi, Christopher Haslett

Br J Pharmacol· January 2009

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