Publications by authors named "Helene Descamps"

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Epigenetic adaptation of beta cells across lifespan and disease: age-related demethylation is advanced in type 2 diabetes.
Elisabetta Manduchi, Hélène C Descamps, Jinping Liu, Jonathan Schug, Tong Da

bioRxiv· July 2025

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Gut metagenomes reveal interactions between dietary restriction, ageing and the microbiome in genetically diverse mice.
Lev Litichevskiy, Maya Considine, Jasleen Gill, Vasuprada Shandar, Timothy O Cox, Hélène C Descamps

Nat Microbiol· May 2025

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Response to Comment on Manduchi et al. No Evidence for Persistent Enteroviral B Infection of Pancreatic Islets in Patients With Type 1 Diabetes and Prediabetes From RNA Sequencing Data. Diabetes 2024;73:1697-1704.
Elisabetta Manduchi, Hélène C Descamps, Jonathan Schug, Tong Da, Deeksha Lahori

Diabetes· March 2025

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Spatiotemporal dynamics during niche remodeling by super-colonizing microbiota in the mammalian gut.
Guillaume Urtecho, Thomas Moody, Yiming Huang, Ravi U Sheth, Miles Richardson, Hélène C Descamps

Cell Syst· November 2024

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No Evidence for Persistent Enteroviral B Infection of Pancreatic Islets in Patients With Type 1 Diabetes and Prediabetes From RNA Sequencing Data.
Elisabetta Manduchi, Hélène C Descamps, Jonathan Schug, Tong Da, Deeksha Lahori

Diabetes· October 2024

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Astrocyte TrkB promotes brain injury and edema formation in ischemic stroke.
Emanuela Colombo, Marco Bacigaluppi, Michela Bartoccetti, Daniela Triolo, Claudia Bassani, Hélène C Descamps

Neurobiol Dis· October 2024

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Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke.
Jia Nong, Patrick M Glassman, Vladimir V Shuvaev, Sahily Reyes-Esteves, Helene C Descamps

Mol Ther· May 2024

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Modeling type 1 diabetes progression using machine learning and single-cell transcriptomic measurements in human islets.
Abhijeet R Patil, Jonathan Schug, Chengyang Liu, Deeksha Lahori, Hélène C Descamps

Cell Rep Med· May 2024

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A subpopulation of lipogenic brown adipocytes drives thermogenic memory.
Patrick Lundgren, Prateek V Sharma, Lenka Dohnalová, Kyle Coleman, Giulia T Uhr, Hélène C Descamps

Nat Metab· October 2023

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Serotonin reduction in post-acute sequelae of viral infection.
Andrea C Wong, Ashwarya S Devason, Iboro C Umana, Timothy O Cox, Lenka Dohnalová, Hélène C Descamps

Cell· October 2023

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The enteric nervous system relays psychological stress to intestinal inflammation.
Kai Markus Schneider, Niklas Blank, Yelina Alvarez, Katharina Thum, Patrick Lundgren, Hélène C Descamps

Cell· June 2023

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Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke.
Jia Nong, Patrick M Glassman, Sahily Reyes-Esteves, Helene C Descamps, Vladimir V Shuvaev

bioRxiv· June 2023

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NAD precursors cycle between host tissues and the gut microbiome.
Karthikeyani Chellappa, Melanie R McReynolds, Wenyun Lu, Xianfeng Zeng, Mikhail Makarov, Hélène C Descamps

Cell Metab· December 2022

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A microbiome-dependent gut-brain pathway regulates motivation for exercise.
Lenka Dohnalová, Patrick Lundgren, Jamie R E Carty, Nitsan Goldstein, Sebastian L Wenski, Hélène C Descamps

Nature· December 2022

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β-Hydroxybutyrate suppresses colorectal cancer.
Oxana Dmitrieva-Posocco, Andrea C Wong, Patrick Lundgren, Aleksandra M Golos, Hélène C Descamps

Nature· May 2022

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NAD flux is maintained in aged mice despite lower tissue concentrations.
Melanie R McReynolds, Karthikeyani Chellappa, Eric Chiles, Connor Jankowski, Yihui Shen, Hélène C Descamps

Cell Syst· December 2021

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Interferon-γ/Interleukin-27 Axis Induces Programmed Death Ligand 1 Expression in Monocyte-Derived Dendritic Cells and Restores Immune Tolerance in Central Nervous System Autoimmunity.
Giacomo Casella, Javad Rasouli, Rodolfo Thome, Hélène C Descamps, Asrita Vattikonda

Front Immunol· June 2021

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Pharmacological activation of STING blocks SARS-CoV-2 infection.
Minghua Li, Max Ferretti, Baoling Ying, Hélène Descamps, Emily Lee

Sci Immunol· May 2021

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Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.
Diego Adhemar Jaitin, Lorenz Adlung, Christoph A Thaiss, Assaf Weiner, Baoguo Li, Hélène Descamps

Cell· July 2019

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The path toward using microbial metabolites as therapies.
Hélène C Descamps, Beatrice Herrmann, Daphne Wiredu, Christoph A Thaiss

EBioMedicine· June 2019

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Extracellular Vesicles Containing IL-4 Modulate Neuroinflammation in a Mouse Model of Multiple Sclerosis.
Giacomo Casella, Federico Colombo, Annamaria Finardi, Hélène Descamps, Gerard Ill-Raga

Mol Ther· September 2018

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Intestinal Tolerance, with a Little Help from Our Microbial Friends.
Hélène Descamps, Christoph A Thaiss

Immunity· July 2018

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IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression.
Giacomo Casella, Annamaria Finardi, Hélène Descamps, Federico Colombo, Chiara Maiorino

Sci Rep· November 2017

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