Publications by authors named "Herve Coste"

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Discovery and characterization of small molecule inhibitors of the BET family bromodomains.
Chun-Wa Chung, Herve Coste, Julia H White, Olivier Mirguet, Jonathan Wilde

J Med Chem· June 2011

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Suppression of inflammation by a synthetic histone mimic.
Edwige Nicodeme, Kate L Jeffrey, Uwe Schaefer, Soren Beinke, Scott Dewell, Hervé Coste

Nature· December 2010

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Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity.
Marie-Hélène Fouchet, Frédéric Donche, Christelle Martin, Anne Bouillot, Christophe Junot, Hervé Coste

Bioorg Med Chem· June 2008

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Hepatocyte nuclear factor-4alpha regulates the human apolipoprotein AV gene: identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-gamma coactivator-1alpha, AMP-activated protein kinase, and mitogen-activated protein kinase pathway.
Xavier Prieur, Frank G Schaap, Hervé Coste, Joan C Rodríguez

Mol Endocrinol· December 2005

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Thyroid hormone regulates the hypotriglyceridemic gene APOA5.
Xavier Prieur, Thierry Huby, Hervé Coste, Frank G Schaap, M John Chapman

J Biol Chem· July 2005

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The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione analogues.
Alain Daugan, Pascal Grondin, Cécile Ruault, Anne-Charlotte Le Monnier de Gouville, Hervé Coste

J Med Chem· October 2003

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The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues.
Alain Daugan, Pascal Grondin, Cécile Ruault, Anne-Charlotte Le Monnier de Gouville, Hervé Coste

J Med Chem· October 2003

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The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element.
Xavier Prieur, Herve Coste, Joan C Rodriguez

J Biol Chem· July 2003

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Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter.
Hervé Coste, Joan C Rodríguez

J Biol Chem· July 2002

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