Publications by authors named "HoMan Chan"

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I
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
Matthew J LaMarche, Michael Acker, Andreea Argintaru, Daniel Bauer, Julie Boisclair, Homan Chan

J Med Chem· November 2020

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C
Correction to Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
Jeffrey T Bagdanoff, Zhouliang Chen, Michael Acker, Ying-Nan Chen, Homan Chan

J Med Chem· April 2019

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C
Correction to 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.
Patrick Sarver, Michael Acker, Jeffrey T Bagdanoff, Zhouliang Chen, Ying-Nan Chen, Homan Chan

J Med Chem· April 2019

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6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.
Patrick Sarver, Michael Acker, Jeffrey T Bagdanoff, Zhouliang Chen, Ying-Nan Chen, Homan Chan

J Med Chem· February 2019

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Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
Jeffrey T Bagdanoff, Zhouliang Chen, Michael Acker, Ying-Nan Chen, Homan Chan

J Med Chem· February 2019

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A
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, HoMan Chan

Nat Chem Biol· April 2017

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A chemical genetics approach for the functional assessment of novel cancer genes.
Qianhe Zhou, Adnan Derti, David Ruddy, Daniel Rakiec, Iris Kao, HoMan Chan

Cancer Res· May 2015

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Direct quantification of circulating miRNAs in different stages of nasopharyngeal cancerous serum samples in single molecule level with total internal reflection fluorescence microscopy.
See-Lok Ho, Ho-Man Chan, Amber Wai-Yan Ha, Ricky Ngok-Shun Wong, Hung-Wing Li

Anal Chem· October 2014

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Self-assembling protein platform for direct quantification of circulating microRNAs in serum with total internal reflection fluorescence microscopy.
See-Lok Ho, Ho-Man Chan, Ricky Ngok-Shun Wong, Hung-Wing Li

Anal Chim Acta· May 2014

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M
Monitoring of DNA-protein interaction with single gold nanoparticles by localized scattering plasmon resonance spectroscopy.
Kin-Man Lo, Chung-Yin Lai, Ho-Man Chan, Dik-Lung Ma, Hung-Wing Li

Methods· December 2013

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N
NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma.
Zheng Huang, Haiping Wu, Shannon Chuai, Fiona Xu, Feng Yan, Homan Chan

Cancer Res· October 2013

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N-Acetyl-l-cysteine capped quantum dots offer neuronal cell protection by inhibiting beta (1-40) amyloid fibrillation.
Olivia T W Ng, Yi Wong, Ho-Man Chan, Jing Cheng, Xiao Qi, Wing-Hong Chan

Biomater Sci· June 2013

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Folate-conjugated FeO@SiO@gold nanorods@mesoporous SiO hybrid nanomaterial: a theranostic agent for magnetic resonance imaging and photothermal therapy.
Da-Wei Wang, Xiao-Ming Zhu, Siu-Fung Lee, Ho-Man Chan, Hung-Wing Li

J Mater Chem B· June 2013

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S
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation.
Wei Qi, HoMan Chan, Lin Teng, Ling Li, Shannon Chuai

Proc Natl Acad Sci U S A· December 2012

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E
Effect of surface-functionalized nanoparticles on the elongation phase of beta-amyloid (1-40) fibrillogenesis.
Ho-Man Chan, Lehui Xiao, Kai-Ming Yeung, See-Lok Ho, Dan Zhao, Wing-Hong Chan

Biomaterials· June 2012

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Multifunctional encoded self-assembling protein nanofibrils as platform for high-throughput and multiplexed detection of biomolecules.
Ho-Man Chan, Hung-Wing Li

Anal Chem· December 2011

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H
Histone methylation by PRC2 is inhibited by active chromatin marks.
Frank W Schmitges, Archana B Prusty, Mahamadou Faty, Alexandra Stützer, Gondichatnahalli M Lingaraju, Homan Chan

Mol Cell· May 2011

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D
Direct quantification of single-molecules of microRNA by total internal reflection fluorescence microscopy.
Ho-Man Chan, Lai-Sheung Chan, Ricky Ngok-Shun Wong, Hung-Wing Li

Anal Chem· August 2010

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P
p400 is required for E1A to promote apoptosis.
Andrew V Samuelson, Masako Narita, Ho-Man Chan, Jianping Jin, Elisa de Stanchina

J Biol Chem· June 2005

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E
E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.
Stefan Taubert, Chiara Gorrini, Scott R Frank, Tiziana Parisi, Miriam Fuchs, Ho-Man Chan

Mol Cell Biol· May 2004

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M
MYC recruits the TIP60 histone acetyltransferase complex to chromatin.
Scott R Frank, Tiziana Parisi, Stefan Taubert, Paula Fernandez, Miriam Fuchs, Ho-Man Chan

EMBO Rep· June 2003

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