Publications by authors named "Holger Cynis"

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3D-printed microstructured alginate scaffolds for neural tissue engineering.
Jianfeng Li, Benjamin Hietel, Michael G K Brunk, Armin Reimers, Christian Willems, Holger Cynis

Trends Biotechnol· February 2025

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Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activity.
Alexandra Herrmann, Christian Gege, Christina Wangen, Sabrina Wagner, Melanie Kögler, Holger Cynis

Antiviral Res· November 2024

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Dipeptidyl peptidase 4 deficiency improves survival after focal cerebral ischemia in mice and ameliorates microglia activation and specific inflammatory markers.
Corinna Höfling, Philippa Donkersloot, Luise Ulrich, Sina Burghardt, Michael Opitz, Holger Cynis

Neurobiol Dis· October 2024

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Identification of isoaspartate-modified transthyretin as potential target for selective immunotherapy of transthyretin amyloidosis.
Janett Köppen, Martin Kleinschmidt, Markus Morawski, Jens-Ulrich Rahfeld, Michael Wermann, Holger Cynis

Amyloid· September 2024

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Focal Cerebral Ischemia Induces Expression of Glutaminyl Cyclase along with Downstream Molecular and Cellular Inflammatory Responses.
Corinna Höfling, Luise Ulrich, Sina Burghardt, Philippa Donkersloot, Michael Opitz, Holger Cynis

Cells· August 2024

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Consequences of Amyloid-β Deficiency for the Liver.
Gayane Hrachia Buniatian, Ute Schwinghammer, Roman Tremmel, Holger Cynis, Thomas S Weiss

Adv Sci (Weinh)· May 2024

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A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice.
Susan Barendrecht, An Schreurs, Stefanie Geissler, Victor Sabanov, Victoria Ilse, Holger Cynis

Alzheimers Res Ther· January 2023

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Immunogenicity of the Envelope Surface Unit of Human Endogenous Retrovirus K18 in Mice.
Victoria Ilse, Rebekka Scholz, Michael Wermann, Marcel Naumann, Martin S Staege, Holger Cynis

Int J Mol Sci· July 2022

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Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice.
Kathrin Gnoth, Stefanie Geissler, Julia Feldhaus, Nadine Taudte, Victoria Ilse, Holger Cynis

Biomolecules· March 2022

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Endogenous Retroviral-K Envelope Is a Novel Tumor Antigen and Prognostic Indicator of Renal Cell Carcinoma.
Veronika Weyerer, Pamela L Strissel, Christine Stöhr, Markus Eckstein, Sven Wach, Holger Cynis

Front Oncol· April 2021

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Identification of Differentially Expressed Human Endogenous Retrovirus Families in Human Leukemia and Lymphoma Cell Lines and Stem Cells.
Kristina Engel, Lisa Wieland, Anna Krüger, Ines Volkmer, Holger Cynis

Front Oncol· April 2021

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Endogenous Retroviruses in Nervous System Disorders.
Victoria Gröger, Alexander Emmer, Martin S Staege, Holger Cynis

Pharmaceuticals (Basel)· January 2021

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Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life.
Ruth E Uhlmann, Christine Rother, Jay Rasmussen, Juliane Schelle, Carina Bergmann, Holger Cynis

Nat Neurosci· December 2020

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Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology.
Kathrin Gnoth, Anke Piechotta, Martin Kleinschmidt, Sandra Konrath, Mathias Schenk, Holger Cynis

Alzheimers Res Ther· November 2020

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Formation of HERV-K and HERV-Fc1 Envelope Family Members is Suppressed on Transcriptional and Translational Level.
Victoria Gröger, Lisa Wieland, Marcel Naumann, Ann-Christin Meinecke, Beate Meinhardt, Holger Cynis

Int J Mol Sci· October 2020

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Viromers as carriers for mRNA-mediated expression of therapeutic molecules under inflammatory conditions.
Edith Jansig, Stefanie Geissler, Vera Rieckmann, Anja Kuenemund, Benjamin Hietel, Holger Cynis

Sci Rep· September 2020

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Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver.
Gayane Hrachia Buniatian, Ralf Weiskirchen, Thomas S Weiss, Ute Schwinghammer, Martin Fritz, Holger Cynis

Cells· February 2020

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Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity.
Claudia Lienau, Tobias Gräwert, Leandro A Alves Avelar, Boris Illarionov, Jana Held, Holger Cynis

Eur J Med Chem· November 2019

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Dipeptidyl-Peptidase Activity of Meprin β Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ Formation.
Dagmar Schlenzig, Holger Cynis, Maike Hartlage-Rübsamen, Ulrike Zeitschel, Katja Menge

J Alzheimers Dis· September 2019

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Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells.
Marie Barth, Victoria Gröger, Holger Cynis, Martin Sebastian Staege

Mol Biol Rep· April 2019

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Kallikrein-related peptidases are activators of the CC chemokine CCL14.
Mario Grünberg, Dagmar Quandt, Holger Cynis, Hans-Ulrich Demuth, Andrea Kindermann

Eur J Immunol· September 2018

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Structure-Guided Design, Synthesis, and Characterization of Next-Generation Meprin β Inhibitors.
Daniel Ramsbeck, Antje Hamann, Georg Richter, Dagmar Schlenzig, Stefanie Geissler, Holger Cynis

J Med Chem· May 2018

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Human Endogenous Retroviruses and Their Putative Role in the Development of Autoimmune Disorders Such as Multiple Sclerosis.
Victoria Gröger, Holger Cynis

Front Microbiol· February 2018

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N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity.
Astrid Kehlen, Monique Haegele, Livia Böhme, Holger Cynis, Torsten Hoffmann

Biosci Rep· August 2017

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Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges.
Holger Cynis, Jeffrey L Frost, Helen Crehan, Cynthia A Lemere

Mol Neurodegener· June 2016

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