Publications by authors named "Hyunmoon Back"

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Characterization of Apixaban Pharmacokinetics/Pharmacodynamics and Dose Assessment in Pediatric Patients with Congenital or Acquired Heart Disease.
Antoinette Ajavon-Hartmann, Praneeth Jarugula, Hyunmoon Back, Obinna Obianom, Elizabeth Ludwig

Clin Pharmacol Ther· August 2025

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Quantitative Model-Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation.
Wangda Zhou, Emily Bozenhardt, Gregory E Alexander, Matthew L Zierhut, Samira Merali, Hyunmoon Back

Clin Pharmacol Ther· August 2025

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Absolute oral bioavailability of milvexian spray-dried dispersion formulation under fasted and fed conditions in healthy adult participants: An intravenous microtracer approach.
Praneeth Jarugula, Sharif Soleman, Hyunmoon Back, Lisa J Christopher, Dara Hawthorne

Clin Transl Sci· October 2024

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Recommendation of mavacamten posology by model-based analyses in adults with obstructive hypertrophic cardiomyopathy.
Samira Merali, David H Salinger, Maria Palmisano, Amy J Sehnert, Neelima Thanneer, Hyunmoon Back

CPT Pharmacometrics Syst Pharmacol· September 2024

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Characterization of mavacamten pharmacokinetics in patients with hypertrophic cardiomyopathy to inform dose titration.
Peter Chang, Vidya Perera, David H Salinger, Samira Merali, Neelima Thanneer, Hyunmoon Back

CPT Pharmacometrics Syst Pharmacol· September 2024

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Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System.
Manting Chiang, Hyunmoon Back, Jong Bong Lee, Sarah Oh, Tiffany Guo

Pharm Res· July 2024

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A Reactive Oxygen Species-Scavenging 'Stealth' Polymer, Poly(thioglycidyl glycerol), Outperforms Poly(ethylene glycol) in Protein Conjugates and Nanocarriers and Enhances Protein Stability to Environmental and Biological Stressors.
Richard d'Arcy, Farah El Mohtadi, Nora Francini, Carlisle R DeJulius, Hyunmoon Back

J Am Chem Soc· November 2022

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Evaluation and enhancement of standard equations for renal function estimation in individuals with components of metabolic disease.
Luigi Brunetti, Hyunmoon Back, Sijia Yu, Urma Jalil, Leonid Kagan

BMC Nephrol· November 2021

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Pharmacokinetics of eperisone following oral administration in healthy Korean volunteers.
In-Hwan Baek, Hyun-Moon Back, Jung-Woo Chae, Eun-Sol Ha, Heejun Park

Biopharm Drug Dispos· March 2021

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Plasma and cerebrospinal fluid pharmacokinetics of ondansetron in humans.
Manting D Chiang, Karen Frey, Chris Lee, Evan D Kharasch, Dani Tallchief, Hyunmoon Back

Br J Clin Pharmacol· February 2021

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Population Pharmacokinetic Method to Predict Within-Subject Variability Using Single-Period Clinical Data.
Won-Ho Kang, Jae-Yeon Lee, Jung-Woo Chae, Kyeong-Ryoon Lee, In-Hwan Baek, Hyun-Moon Back

Pharmaceuticals (Basel)· February 2021

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Clinical Evaluation of Acetaminophen-Galgeuntang Interaction Based on Population Approaches.
Quyen Thi Tran, So Jung Park, Hyun-Moon Back, Lien Thi Ngo, Duc Tuan Cao

Pharmaceutics· December 2020

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Beyond the Michaelis-Menten: Accurate Prediction of In Vivo Hepatic Clearance for Drugs With Low K.
Hyun-Moon Back, Hwi-Yeol Yun, Sang Kyum Kim, Jae Kyoung Kim

Clin Transl Sci· November 2020

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Development of a Pharmacokinetic Model Describing Neonatal Fc Receptor-Mediated Recycling of HL2351, a Novel Hybrid Fc-Fused Interleukin-1 Receptor Antagonist, to Optimize Dosage Regimen.
Lien Ngo, Jaeseong Oh, Anhye Kim, Hyun-Moon Back, Won-Ho Kang

CPT Pharmacometrics Syst Pharmacol· October 2020

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Pharmacokinetic Modeling of the Impact of P-glycoprotein on Ondansetron Disposition in the Central Nervous System.
Manting Chiang, Hyun-Moon Back, Jong Bong Lee, Sarah Oh, Tiffany Guo

Pharm Res· September 2020

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Pharmacokinetics of Shikimic Acid Following Intragastric and Intravenous Administrations in Rats.
Keumhan Noh, Hyun-Moon Back, Beom Soo Shin, Wonku Kang

Pharmaceutics· August 2020

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Redox Imbalance and Oxidative DNA Damage During Isoniazid Treatment of HIV-Associated Tuberculosis: A Clinical and Translational Pharmacokinetic Study.
Isaac Zentner, Hyun-Moon Back, Leonid Kagan, Selvakumar Subbian, Jyothi Nagajyothi

Front Pharmacol· July 2020

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Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients.
Hyun-Moon Back, Jong Bong Lee, Anhye Kim, Seon-Jong Park, Junyeong Kim

Pharmaceutics· April 2020

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Application of an Inter-Species Extrapolation Method for the Prediction of Drug Interactions between Propolis and Duloxetine in Humans.
Thi Lien Ngo, Chung-Hee Lee, Nayoung Han, Hyun-Moon Back, Su-Jin Rhee

Int J Mol Sci· March 2020

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Application of Size and Maturation Functions to Population Pharmacokinetic Modeling of Pediatric Patients.
Hyun-Moon Back, Jong Bong Lee, Nayoung Han, Sungwoo Goo, Eben Jung

Pharmaceutics· June 2019

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Dose Optimization Based on Population Pharmacokinetic Modeling of High-Dose Cyclosporine, a P-glycoprotein Inhibitor, in Combination with Systemic Chemotherapy in Pediatric Patients with Retinoblastoma.
Yoon Sun Ree, Hyun-Moon Back, Hwi-Yeol Yun, Ji Hyun Ahn, Eun Sun Son

J Ocul Pharmacol Ther· November 2018

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Prediction of Methionine and Homocysteine levels in Zucker diabetic fatty (ZDF) rats as a T2DM animal model after consumption of a Methionine-rich diet.
Nayoung Han, Jung-Woo Chae, Jihyun Jeon, Jaeyeon Lee, Hyun-Moon Back

Nutr Metab (Lond)· February 2018

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A mechanism-based pharmacokinetic model of fenofibrate for explaining increased drug absorption after food consumption.
Hyun-Moon Back, Byungjeong Song, Sudeep Pradhan, Jung-Woo Chae, Nayoung Han

BMC Pharmacol Toxicol· January 2018

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Performance comparison of first-order conditional estimation with interaction and Bayesian estimation methods for estimating the population parameters and its distribution from data sets with a low number of subjects.
Sudeep Pradhan, Byungjeong Song, Jaeyeon Lee, Jung-Woo Chae, Kyung Im Kim, Hyun-Moon Back

BMC Med Res Methodol· December 2017

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BSA and ABCB1 polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen.
Jung-Woo Chae, Yi Ling Teo, Han Kiat Ho, Jaeyeon Lee, Hyun-Moon Back

Cancer Chemother Pharmacol· September 2016

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