Publications by authors named "Ian Overton"

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A Computationally Optimised Structural Integrity Sequence Enhances Vaccine Stability, Yield and Safety Profile.
Arthur Sarron, Sun B Sowers, Yaroslav Tsybovsky, Heather Colley, Stephen N Crooke, Ian M Overton

Res Sq· September 2025

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ieGENES: A machine learning method for selecting differentially expressed genes in cancer studies.
Xiao-Lei Xia, Shang-Ming Zhou, Yunguang Liu, Na Lin, Ian M Overton

J Biomed Inform· April 2025

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Validation of In Vitro Trained Transcriptomic Radiosensitivity Signatures in Clinical Cohorts.
John D O'Connor, Ian M Overton, Stephen J McMahon

Cancers (Basel)· July 2023

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Transcriptome Profiling Reveals Enhanced Mitochondrial Activity as a Cold Adaptive Strategy to Hypothermia in Zebrafish Muscle.
Thomas Cahill, Sherine Chan, Ian M Overton, Gary Hardiman

Cells· May 2023

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Investigating the effects of chronic low-dose radiation exposure in the liver of a hypothermic zebrafish model.
Thomas Cahill, Willian Abraham da Silveira, Ludivine Renaud, Hao Wang, Tucker Williamson, Ian Overton

Sci Rep· January 2023

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Strategies and techniques for quality control and semantic enrichment with multimodal data: a case study in colorectal cancer with eHDPrep.
Tom M Toner, Rashi Pancholi, Paul Miller, Thorsten Forster, Helen G Coleman, Ian M Overton

Gigascience· December 2022

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PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate.
Helen M Wise, Adam Harris, Nisha Kriplani, Adam Schofield, Helen Caldwell, Ian M Overton

Biomolecules· October 2022

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Immune Cell Networks Uncover Candidate Biomarkers of Melanoma Immunotherapy Response.
Duong H T Vo, Gerard McGleave, Ian M Overton

J Pers Med· June 2022

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RadSigBench: a framework for benchmarking functional genomics signatures of cancer cell radiosensitivity.
John D O'Connor, Ian M Overton, Stephen J McMahon

Brief Bioinform· March 2022

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Long non-coding RNAs and their potential impact on diagnosis, prognosis, and therapy in prostate cancer: racial, ethnic, and geographical considerations.
Rebecca Morgan, Willian Abraham da Silveira, Ryan Christopher Kelly, Ian Overton, Emma H Allott

Expert Rev Mol Diagn· December 2021

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SynLeGG: analysis and visualization of multiomics data for discovery of cancer 'Achilles Heels' and gene function relationships.
Mark Wappett, Adam Harris, Alexander L R Lubbock, Ian Lobb, Simon McDade, Ian M Overton

Nucleic Acids Res· July 2021

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Induced Torpor as a Countermeasure for Low Dose Radiation Exposure in a Zebrafish Model.
Thomas Cahill, Willian Abraham da Silveira, Ludivine Renaud, Tucker Williamson, Hao Wang, Ian Overton

Cells· April 2021

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Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling.
Ian M Overton, Andrew H Sims, Jeremy A Owen, Bret S E Heale, Matthew J Ford

Cancers (Basel)· September 2020

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Quantitative Shotgun Proteomics Unveils Candidate Novel Esophageal Adenocarcinoma (EAC)-specific Proteins.
J Robert O'Neill, Hui-Song Pak, Erola Pairo-Castineira, Vicki Save, Simon Paterson-Brown, Ian Overton

Mol Cell Proteomics· June 2017

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Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer.
Alexander L R Lubbock, Grant D Stewart, Fiach C O'Mahony, Alexander Laird, Peter Mullen, Ian M Overton

BMC Med· June 2017

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Adaptation services of floodplains and wetlands under transformational climate change.
Matthew Colloff, Sandra Lavorel, Russell M Wise, Michael Dunlop, Ian C Overton

Ecol Appl· June 2016

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Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer.
Grant D Stewart, Fiach C O'Mahony, Alexander Laird, Lel Eory, Alexander L R Lubbock, Ian M Overton

Clin Cancer Res· September 2015

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Carbonic anhydrase 9 expression increases with vascular endothelial growth factor-targeted therapy and is predictive of outcome in metastatic clear cell renal cancer.
Grant D Stewart, Fiach C O'Mahony, Alexander Laird, Sukaina Rashid, Sarah A Martin, Ian M Overton

Eur Urol· November 2014

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The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster.
Xianghua Li, Ian M Overton, Richard A Baines, Liam P Keegan, Mary A O'Connell

Nucleic Acids Res· January 2014

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TMA Navigator: Network inference, patient stratification and survival analysis with tissue microarray data.
Alexander L R Lubbock, Elad Katz, David J Harrison, Ian M Overton

Nucleic Acids Res· July 2013

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The use of reverse phase protein arrays (RPPA) to explore protein expression variation within individual renal cell cancers.
Fiach C O'Mahony, Jyoti Nanda, Alexander Laird, Peter Mullen, Helen Caldwell, Ian M Overton

J Vis Exp· January 2013

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Addressing statistical biases in nucleotide-derived protein databases for proteogenomic search strategies.
Paul Blakeley, Ian M Overton, Simon J Hubbard

J Proteome Res· November 2012

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Computational approaches to selecting and optimising targets for structural biology.
Ian M Overton, Geoffrey J Barton

Methods· September 2011

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Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus.
Ian M Overton, Shirley Graham, Katherine A Gould, Jason Hinds, Catherine H Botting

BMC Syst Biol· May 2011

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XANNpred: neural nets that predict the propensity of a protein to yield diffraction-quality crystals.
Ian M Overton, C A Johannes van Niekerk, Geoffrey J Barton

Proteins· April 2011

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