Publications by authors named "Ignacio Cotillo"

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Short-course combination treatment for experimental chronic Chagas disease.
Silvia González, Richard J Wall, John Thomas, Stephanie Braillard, Gino Brunori, Ignacio Cotillo

Sci Transl Med· December 2023

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Novel Diarylthioether Compounds as Agents for the Treatment of Chagas Disease.
Julia Beveridge, Eric Tran, Girdhar Singh Deora, Fei Huang, Yuzhi Wang, Ignacio Cotillo

J Med Chem· January 2023

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Discovery of pyrazolopyrrolidinones as potent, broad-spectrum inhibitors of infection.
John A Kavouris, Laura-Isobel McCall, Miriam A Giardini, Geraldine De Muylder, Diane Thomas, Ignacio Cotillo

Front Trop Dis· January 2023

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Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.
Kate McGonagle, Gary J Tarver, Juan Cantizani, Ignacio Cotillo, Peter G Dodd

Eur J Med Chem· August 2022

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Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Application to GSK Chagas Box.
Juan Cantizani, Pablo Gamallo, Ignacio Cotillo, Raquel Alvarez-Velilla, Julio Martin

PLoS Negl Trop Dis· July 2021

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The Q Site of Cytochrome is a Promiscuous Drug Target in and .
Richard J Wall, Sandra Carvalho, Rachel Milne, Juan A Bueren-Calabuig, Sonia Moniz, Ignacio Cotillo

ACS Infect Dis· March 2020

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Chagas Disease Drug Discovery: Multiparametric Lead Optimization against in Acylaminobenzothiazole Series.
Charlotte Fleau, Angel Padilla, Juan Miguel-Siles, Maria T Quesada-Campos, Isabel Saiz-Nicolas, Ignacio Cotillo

J Med Chem· November 2019

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Novel chemical starting points for drug discovery in leishmaniasis and Chagas disease.
Irene Roquero, Juan Cantizani, Ignacio Cotillo, M Pilar Manzano, Albane Kessler

Int J Parasitol Drugs Drug Resist· August 2019

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Quinoxaline derivatives as potential antitrypanosomal and antileishmanial agents.
Juliana Cogo, Juan Cantizani, Ignacio Cotillo, Diego Pereira Sangi, Arlene Gonçalves Corrêa

Bioorg Med Chem· August 2018

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Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas' disease drug discovery.
Lorna M MacLean, John Thomas, Michael D Lewis, Ignacio Cotillo, David W Gray

PLoS Negl Trop Dis· July 2018

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Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.
Stephanie Russell, Raphaël Rahmani, Amy J Jones, Harriet L Newson, Kevin Neilde, Ignacio Cotillo

J Med Chem· November 2016

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New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.
Imanol Peña, M Pilar Manzano, Juan Cantizani, Albane Kessler, Julio Alonso-Padilla, Ignacio Cotillo

Sci Rep· March 2015

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Automated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell line.
Julio Alonso-Padilla, Ignacio Cotillo, Jesús L Presa, Juan Cantizani, Imanol Peña

PLoS Negl Trop Dis· January 2015

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Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells.
Luis M Alonso-C, Eva M A Trinidad, Beatriz de Garcillan, Monica Ballesteros, Milagros Castellanos, Ignacio Cotillo

Leuk Res· March 2009

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