Publications by authors named "Igor Shats"

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Host-microbe interactions in NAD metabolism.
Xiaoyue Wu, Igor Shats, Xiaoling Li

Trends Mol Med· July 2025

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Methionine restriction-induced sulfur deficiency impairs antitumour immunity partially through gut microbiota.
Ming Ji, Xiaojiang Xu, Qing Xu, Yun-Chung Hsiao, Cody Martin, Igor Shats

Nat Metab· September 2023

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DNASE1L3 enhances antitumor immunity and suppresses tumor progression in colon cancer.
Wenling Li, Hideki Nakano, Wei Fan, Yuanyuan Li, Payel Sil, Igor Shats

JCI Insight· September 2023

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Predicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines.
Yuanyuan Li, David M Umbach, Juno M Krahn, Igor Shats, Xiaoling Li

BMC Genomics· April 2021

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Bacteria boost host NAD metabolism.
Igor Shats, Xiaoling Li

Aging (Albany NY)· December 2020

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HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.
Qing Xu, Yuanyuan Li, Xia Gao, Kai Kang, Jason G Williams, Igor Shats

Nat Commun· August 2020

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Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway.
Igor Shats, Jason G Williams, Juan Liu, Mikhail V Makarov, Xiaoyue Wu

Cell Metab· March 2020

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Glypican 6 is a putative biomarker for metastatic progression of cutaneous melanoma.
Yuanyuan Li, Melissa Li, Igor Shats, Juno M Krahn, Gordon P Flake

PLoS One· February 2020

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CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data.
Kai Kang, Qian Meng, Igor Shats, David M Umbach, Melissa Li

PLoS Comput Biol· December 2019

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Expression level is a key determinant of E2F1-mediated cell fate.
Igor Shats, Michael Deng, Adam Davidovich, Carolyn Zhang, Jungeun S Kwon

Cell Death Differ· April 2017

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E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program.
Xiaolei Jiang, Joseph Roy Nevins, Igor Shats, Jen-Tsan Chi

PLoS One· May 2016

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p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways.
Maria Shatz, Igor Shats, Daniel Menendez, Michael A Resnick

Oncotarget· July 2015

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FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function.
Igor Shats, Michael L Gatza, Beiyu Liu, Steven P Angus, Lingchong You

Cancer Res· October 2013

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Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repression.
Beiyu Liu, Igor Shats, Steven P Angus, Michael L Gatza, Joseph R Nevins

J Biol Chem· August 2013

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Using a stem cell-based signature to guide therapeutic selection in cancer.
Igor Shats, Michael L Gatza, Jeffrey T Chang, Seiichi Mori, Jialiang Wang

Cancer Res· March 2011

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p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner.
Alina Molchadsky, Igor Shats, Naomi Goldfinger, Meirav Pevsner-Fischer, Melissa Olson

PLoS One· December 2008

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Myocardin in tumor suppression and myofibroblast differentiation.
Igor Shats, Michael Milyavsky, Alina Cholostoy, Ran Brosh, Varda Rotter

Cell Cycle· May 2007

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Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.
Michael Milyavsky, Igor Shats, Alina Cholostoy, Ran Brosh, Yosef Buganim

Cancer Cell· February 2007

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Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction.
Yosef Buganim, Eyal Kalo, Ran Brosh, Hila Besserglick, Ido Nachmany, Igor Shats

Cancer Res· November 2006

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The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation.
Yuval Tabach, Michael Milyavsky, Igor Shats, Ran Brosh, Or Zuk

Mol Syst Biol· August 2006

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hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis.
Ira Kogan, Naomi Goldfinger, Michael Milyavsky, Merav Cohen, Igor Shats

Cancer Res· April 2006

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Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation.
Michael Milyavsky, Yuval Tabach, Igor Shats, Neta Erez, Yehudit Cohen

Cancer Res· June 2005

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p53-dependent down-regulation of telomerase is mediated by p21waf1.
Igor Shats, Michael Milyavsky, Xiaohu Tang, Perry Stambolsky, Neta Erez

J Biol Chem· December 2004

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Activated p53 suppresses the histone methyltransferase EZH2 gene.
Xiaohu Tang, Michael Milyavsky, Igor Shats, Neta Erez, Naomi Goldfinger

Oncogene· July 2004

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Hypoxia-dependent regulation of PHD1: cloning and characterization of the human PHD1/EGLN2 gene promoter.
Neta Erez, Perry Stambolsky, Igor Shats, Michael Milyavsky, Tami Kachko

FEBS Lett· June 2004

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