Publications by authors named "Isabelle Dubuc"

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PapMV nanoparticles: A novel pathway to SARS-CoV-2 protection, distinct from Imidazoquinolines.
Marilène Bolduc, Philippe Saint-Louis, Damien Carignan, Caroline Garneau, Yann Breton, Isabelle Dubuc

Nanomedicine· December 2025

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A Benchmark of methods for SARS-CoV-2 whole genome sequencing and development of a more sensitive method.
Anthony Bayega, Sarah J Reiling, Ju Ling Liu, Isabelle Dubuc, Annie Gravel

Front Genet· September 2025

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Delayed viral clearance and altered inflammatory responses affect severity of SARS-CoV-2 infection in aged mice.
Émile Lacasse, Isabelle Dubuc, Leslie Gudimard, Ana Claudia Dos S P Andrade, Annie Gravel

Immun Ageing· March 2025

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Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection.
Ana Claudia Dos S P Andrade, Emile Lacasse, Isabelle Dubuc, Leslie Gudimard, Annie Gravel

Proc Natl Acad Sci U S A· March 2025

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Targeting Cytokines: Evaluating the Potential of Mesenchymal Stem Cell Derived Extracellular Vesicles in the Management of COVID-19.
Iago Carvalho Schultz, Ana Claudia Dos Santos Pereira Andrade, Isabelle Dubuc, Audrée Laroche, Isabelle Allaeys

Stem Cell Rev Rep· February 2025

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SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow.
Isabelle Allaeys, Guillaume Lemaire, Mickaël Leclercq, Emile Lacasse, Maude Fleury, Isabelle Dubuc

Blood Adv· June 2024

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SARS-CoV-2 rapidly evolves lineage-specific phenotypic differences when passaged repeatedly in immune-naïve mice.
Julian Daniel Sunday Willett, Annie Gravel, Isabelle Dubuc, Leslie Gudimard, Ana Claudia Dos Santos Pereira Andrade

Commun Biol· February 2024

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Pharmacological targeting of the hyper-inflammatory response to SARS-CoV-2-infected K18-hACE2 mice using a cluster of differentiation 36 receptor modulator.
Jade Gauvin, David N Huynh, Isabelle Dubuc, Catherine Lê, Rafaela Tugores

Front Pharmacol· February 2024

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SARS-CoV-2 Nsp2 Contributes to Inflammation by Activating NF-κB.
Émile Lacasse, Leslie Gudimard, Isabelle Dubuc, Annie Gravel, Isabelle Allaeys

Viruses· January 2023

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A nanoparticle-based COVID-19 vaccine candidate elicits broad neutralizing antibodies and protects against SARS-CoV-2 infection.
Santa-Mariela Olivera-Ugarte, Marilène Bolduc, Marie-Ève Laliberté-Gagné, Léa-Jeanne Blanchette, Caroline Garneau, Isabelle Dubuc

Nanomedicine· August 2022

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Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice.
Isabelle Dubuc, Julien Prunier, Émile Lacasse, Annie Gravel, Florian Puhm

Front Immunol· July 2022

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Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells.
Florian Puhm, Isabelle Allaeys, Emile Lacasse, Isabelle Dubuc, Yannick Galipeau

Blood Adv· June 2022

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Chemokines and eicosanoids fuel the hyperinflammation within the lungs of patients with severe COVID-19.
Younes Zaid, Étienne Doré, Isabelle Dubuc, Anne-Sophie Archambault, Olivier Flamand

J Allergy Clin Immunol· August 2021

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High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients.
Anne-Sophie Archambault, Younes Zaid, Volatiana Rakotoarivelo, Caroline Turcotte, Étienne Doré, Isabelle Dubuc

FASEB J· June 2021

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Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog.
Pascal Tétreault, Élie Besserer-Offroy, Rebecca L Brouillette, Adeline René, Alexandre Murza, Isabelle Dubuc

Eur J Pharmacol· September 2020

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Data set describing the biological activity of JMV2009, a novel silylated neurotensin(8-13) analog.
Élie Besserer-Offroy, Pascal Tétreault, Rebecca L Brouillette, Adeline René, Alexandre Murza, Isabelle Dubuc

Data Brief· August 2020

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rs73185306 C/T Is Not a Predisposing Risk Factor for Inherited Chromosomally Integrated Human Herpesvirus 6A/B.
Annabelle Mouammine, Annie Gravel, Isabelle Dubuc, Yassamin Feroz Zada, Sylvie Provost

J Infect Dis· March 2020

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Inherited Chromosomally Integrated Human Herpesvirus 6 Demonstrates Tissue-Specific RNA Expression That Correlates with an Increased Antibody Immune Response.
Vikas Peddu, Isabelle Dubuc, Annie Gravel, Hong Xie, Meei-Li Huang

J Virol· December 2019

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Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A.
Anthony J Saviola, Cosima Zimmermann, Michael P Mariani, Sylvia A Signorelli, Diana L Gerrard, Isabelle Dubuc

Front Microbiol· June 2019

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Effect of food deprivation on the hypothalamic gene expression of the secretogranin II-derived peptide EM66 in rat.
Fatima Trebak, Isabelle Dubuc, Marie Picot, Abdelilah Alaoui, Jérôme Leprince

Neuroreport· November 2017

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Cell Culture Systems To Study Human Herpesvirus 6A/B Chromosomal Integration.
Annie Gravel, Isabelle Dubuc, Nina Wallaschek, Shella Gilbert-Girard, Vanessa Collin

J Virol· July 2017

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Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer.
Annie Gravel, Isabelle Dubuc, Angela Brooks-Wilson, Kristan J Aronson, Jacques Simard

Cancer Epidemiol Biomarkers Prev· March 2017

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Neuropeptide Y and α-MSH circadian levels in two populations with low body weight: anorexia nervosa and constitutional thinness.
Bogdan Galusca, Gaëtan Prévost, Natacha Germain, Isabelle Dubuc, Yiin Ling

PLoS One· February 2016

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Characterization of human herpesvirus 6A/B U94 as ATPase, helicase, exonuclease and DNA-binding proteins.
Frédéric Trempe, Annie Gravel, Isabelle Dubuc, Nina Wallaschek, Vanessa Collin

Nucleic Acids Res· July 2015

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Inherited chromosomally integrated human herpesvirus 6 as a predisposing risk factor for the development of angina pectoris.
Annie Gravel, Isabelle Dubuc, Guillaume Morissette, Ruth H Sedlak, Keith R Jerome

Proc Natl Acad Sci U S A· June 2015

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