Publications by authors named "Isabelle LeClerc"

Claim this Profile
B
Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.
Yusman Manchanda, Ben Jones, Gaelle Carrat, Zenouska Ramchunder, Piero Marchetti, Isabelle Leclerc

Diabetes Obes Metab· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Roles for the long non-coding RNA / in pancreatic beta cell function.
Livia Lopez-Noriega, Rebecca Callingham, Aida Martinez-Sánchez, Sameena Nawaz, Grazia Pizza, Isabelle Leclerc

iScience· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Binding Kinetics, Bias, Receptor Internalization and Effects on Insulin Secretion and of a Novel GLP-1R/GIPR Dual Agonist, HISHS-2001.
Yusman Manchanda, Ben Jones, Gaelle Carrat, Zenouska Ramchunder, Piero Marchetti, Isabelle Leclerc

bioRxiv· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Impact of an loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice.
George Firth, Eleni Georgiadou, Alexander Griffiths, Maral Amrahli, Jana Kim, Isabelle Leclerc

Front Endocrinol (Lausanne)· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of biomarkers for glycaemic deterioration in type 2 diabetes.
Roderick C Slieker, Louise A Donnelly, Elina Akalestou, Livia Lopez-Noriega, Rana Melhem, Isabelle Leclerc

Nat Commun· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular phenotyping of single pancreatic islet leader beta cells by "Flash-Seq".
Pauline Chabosseau, Fiona Yong, Luis F Delgadillo-Silva, Eun Young Lee, Rana Melhem, Isabelle Leclerc

Life Sci· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chronic noncancer pain management: Integration of a nurse-led program in primary care.
Metasebia Assefa, Isabelle LeClerc, Elizabeth Muggah, Raywat Deonandan, Charles Godbout

Can Fam Physician· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist.
Ben Jones, Vinod Burade, Elina Akalestou, Yusman Manchanda, Zenouska Ramchunder, Isabelle Leclerc

Diabetes Obes Metab· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice.
Elina Akalestou, Livia Lopez-Noriega, Ioannis Christakis, Ming Hu, Alexander D Miras, Isabelle Leclerc

Front Endocrinol (Lausanne)· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mediastinal Lymph Node Silicotic Nodules and Occupational Exposure to Respirable Crystalline Silica: A Controlled Study in Patients with Lung Cancer.
Patrick Brochard, Hugues Begueret, Matthieu Thumerel, Rachida Bakhiyi, Isabelle Leclerc

Am J Respir Crit Care Med· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Vertical Sleeve Gastrectomy Lowers SGLT2/Slc5a2 Expression in the Mouse Kidney.
Elina Akalestou, Livia Lopez-Noriega, Iain R Tough, Ming Hu, Isabelle Leclerc

Diabetes· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Eleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, Elina Akalestou, Isabelle Leclerc

Diabetes· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function.
Rebecca Cheung, Grazia Pizza, Pauline Chabosseau, Delphine Rolando, Alejandra Tomas, Isabelle Leclerc

Diabetes· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.
Marie-Sophie Nguyen-Tu, Joseph Harris, Aida Martinez-Sanchez, Pauline Chabosseau, Ming Hu, Isabelle Leclerc

Diabetologia· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Author Correction: Intravital imaging of islet Ca dynamics reveals enhanced β cell connectivity after bariatric surgery in mice.
Elina Akalestou, Kinga Suba, Livia Lopez-Noriega, Eleni Georgiadou, Pauline Chabosseau, Isabelle Leclerc

Nat Commun· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intravital imaging of islet Ca dynamics reveals enhanced β cell connectivity after bariatric surgery in mice.
Elina Akalestou, Kinga Suba, Livia Lopez-Noriega, Eleni Georgiadou, Pauline Chabosseau, Isabelle Leclerc

Nat Commun· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Ca -binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6.
Steven Z Parks, Tian Gao, Natalia Jimenez Awuapura, Joseph Ayathamattam, Pauline L Chabosseau, Isabelle Leclerc

FEBS Lett· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.
S Neda Mousavy Gharavy, Bryn M Owen, Steven J Millership, Pauline Chabosseau, Grazia Pizza, Isabelle Leclerc

Diabetologia· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice.
Marie-Sophie Nguyen-Tu, Aida Martinez-Sanchez, Isabelle Leclerc, Guy A Rutter, Gabriela da Silva Xavier

Diabetologia· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis.
Gaelle R Carrat, Elizabeth Haythorne, Alejandra Tomas, Leena Haataja, Andreas Müller, Isabelle Leclerc

Mol Metab· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The pore-forming subunit MCU of the mitochondrial Ca uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice.
Eleni Georgiadou, Elizabeth Haythorne, Matthew T Dickerson, Livia Lopez-Noriega, Timothy J Pullen, Isabelle Leclerc

Diabetologia· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and in vivo behaviour of an exendin-4-based MRI probe capable of β-cell-dependent contrast enhancement in the pancreas.
Thomas J Clough, Nicoleta Baxan, Emma J Coakley, Charlotte Rivas, Lan Zhao, Isabelle Leclerc

Dalton Trans· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
[
[Occupational cancers: Risks and prevention].
Camille Carles, Catherine Verdun-Esquer, Isabelle Leclerc, Isabelle Baldi

Bull Cancer· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Leader β-cells coordinate Ca dynamics across pancreatic islets in vivo.
Victoria Salem, Luis Delgadillo Silva, Kinga Suba, Eleni Georgiadou, S Neda Mousavy Gharavy, Isabelle Leclerc

Nat Metab· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Transcription factor-7-like 2 () gene acts downstream of the kinase to control mTOR signaling, β cell growth, and insulin secretion.
Marie-Sophie Nguyen-Tu, Gabriela da Silva Xavier, Isabelle Leclerc, Guy A Rutter

J Biol Chem· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis