Publications by authors named "Ivan Stone"

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SGN-CD228A Is an Investigational CD228-Directed Antibody-Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models.
Rebecca Mazahreh, Marsha L Mason, John J Gosink, Devra J Olson, Robert Thurman, Ivan J Stone

Mol Cancer Ther· April 2023

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Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific Conjugation.
Joseph Z Hamilton, Thomas A Pires, Jamie A Mitchell, Julia H Cochran, Kim K Emmerton, Ivan J Stone

ChemMedChem· April 2021

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A coiled-coil masking domain for selective activation of therapeutic antibodies.
Vivian H Trang, Xinqun Zhang, Roma C Yumul, Weiping Zeng, Ivan J Stone

Nat Biotechnol· July 2019

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Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia.
Fu Li, May Kung Sutherland, Changpu Yu, Roland B Walter, Lori Westendorf, Ivan J Stone

Mol Cancer Ther· February 2018

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Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.
Sriram Krishnamoorthy, Betty Pace, Dipti Gupta, Sarah Sturtevant, Biaoru Li, Ivan Stone

JCI Insight· October 2017

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Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody-Drug Conjugates.
Fu Li, Michelle Ulrich, Mechthild Jonas, Ivan J Stone, Germein Linares

Mol Cancer Ther· July 2017

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Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug Conjugates.
Patrick J Burke, Joseph Z Hamilton, Scott C Jeffrey, Joshua H Hunter, Svetlana O Doronina, Ivan J Stone

Mol Cancer Ther· January 2017

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Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates.
Patrick J Burke, Joseph Z Hamilton, Thomas A Pires, Jocelyn R Setter, Joshua H Hunter, Ivan J Stone

Mol Cancer Ther· May 2016

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SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML.
May S Kung Sutherland, Roland B Walter, Scott C Jeffrey, Patrick J Burke, Changpu Yu, Ivan Stone

Blood· August 2013

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A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology.
Scott C Jeffrey, Patrick J Burke, Robert P Lyon, David W Meyer, Django Sussman, Ivan J Stone

Bioconjug Chem· July 2013

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Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas.
Hans-Peter Gerber, May Kung-Sutherland, Ivan Stone, Carol Morris-Tilden, Jamie Miyamoto

Blood· April 2009

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Potent anticarcinoma activity of the humanized anti-CD70 antibody h1F6 conjugated to the tubulin inhibitor auristatin via an uncleavable linker.
Ezogelin Oflazoglu, Ivan J Stone, Kristine Gordon, Christopher G Wood, Elizabeth A Repasky

Clin Cancer Res· October 2008

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Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index.
Charlotte F McDonagh, Kristine M Kim, Eileen Turcott, Lindsay L Brown, Lori Westendorf, Ivan Stone

Mol Cancer Ther· September 2008

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Anti-CD30 diabody-drug conjugates with potent antitumor activity.
Kristine M Kim, Charlotte F McDonagh, Lori Westendorf, Lindsay L Brown, Django Sussman, Ivan Stone

Mol Cancer Ther· August 2008

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Effects of dehydroepiandrosterone sulfate and progesterone on spatial learning and memory in young and aged mice.
Karin J Bodensteiner, Ivan J Stone, Loraina L Ghiraldi

J Gen Psychol· July 2008

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Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30.
Ezogelin Oflazoglu, Ivan J Stone, Kristine A Gordon, Iqbal S Grewal, Nico van Rooijen

Blood· December 2007

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Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities.
Julie A McEarchern, Ezogelin Oflazoglu, Leigh Francisco, Charlotte F McDonagh, Kristine A Gordon, Ivan Stone

Blood· February 2007

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Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment.
Charlotte F McDonagh, Eileen Turcott, Lori Westendorf, Jennifer B Webster, Stephen C Alley, Ivan Stone

Protein Eng Des Sel· July 2006

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Development and properties of beta-glucuronide linkers for monoclonal antibody-drug conjugates.
Scott C Jeffrey, Jamie B Andreyka, Starr X Bernhardt, Kim M Kissler, Toni Kline, Ivan J Stone

Bioconjug Chem· July 2006

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