Publications by authors named "Ivars Kalvinsh"

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S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity.
Liga Zvejniece, Baiba Svalbe, Edijs Vavers, Marina Makrecka-Kuka, Elina Makarova, Ivars Kalvinsh

Pharmacol Biochem Behav· September 2017

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R-phenibut binds to the α2-δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects.
Liga Zvejniece, Edijs Vavers, Baiba Svalbe, Grigory Veinberg, Kristina Rizhanova, Ivars Kalvinsh

Pharmacol Biochem Behav· October 2015

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Magnesium nitrate attenuates blood pressure rise in SHR rats.
Reinis Vilskersts, Janis Kuka, Edgars Liepinsh, Helena Cirule, Anita Gulbe, Ivars Kalvinsh

Magnes Res· February 2015

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Mildronate and its neuroregulatory mechanisms: targeting the mitochondria, neuroinflammation, and protein expression.
Vija Klusa, Ulrika Beitnere, Jolanta Pupure, Sergejs Isajevs, Juris Rumaks, Ivars Kalvinsh

Medicina (Kaunas)· December 2014

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Targeting carnitine biosynthesis: discovery of new inhibitors against γ-butyrobetaine hydroxylase.
Kaspars Tars, Janis Leitans, Andris Kazaks, Diana Zelencova, Edgars Liepinsh, Ivars Kalvinsh

J Med Chem· March 2014

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Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.
Mette K Christensen, Kamille D Erichsen, Uffe H Olesen, Jette Tjørnelund, Peter Fristrup, Ivars Kalvinsh

J Med Chem· November 2013

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Search for stroke-protecting agents in endothelin-1-induced ischemic stroke model in rats.
Juris Rumaks, Jolanta Pupure, Simons Svirskis, Sergejs Isajevs, Gunars Duburs, Ivars Kalvinsh

Medicina (Kaunas)· September 2013

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Comparison of the effects of glibenclamide on metabolic parameters, GLUT1 expression, and liver injury in rats with severe and mild streptozotocin-induced diabetes mellitus.
Jelizaveta Sokolovska, Sergejs Isajevs, Olga Sugoka, Jelena Sharipova, Natalia Paramonova, Ivars Kalvinsh

Medicina (Kaunas)· September 2013

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Mildronate enhances learning/memory and changes hippocampal protein expression in trained rats.
Vija Klusa, Ruta Muceniece, Sergejs Isajevs, Darja Isajeva, Ulrika Beitnere, Ivars Kalvinsh

Pharmacol Biochem Behav· May 2013

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The cardioprotective effect of mildronate is diminished after co-treatment with L-carnitine.
Janis Kuka, Reinis Vilskersts, Helena Cirule, Marina Makrecka, Osvalds Pugovics, Ivars Kalvinsh

J Cardiovasc Pharmacol Ther· June 2012

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Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei.
John M Kelly, Martin C Taylor, David Horn, Einars Loza, Ivars Kalvinsh

Bioorg Med Chem Lett· March 2012

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Mildronate as a regulator of protein expression in a rat model of Parkinson's disease.
Sergejs Isajevs, Darja Isajeva, Ulrika Beitnere, Baiba Jansone, Ivars Kalvinsh

Medicina (Kaunas)· February 2012

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Administration of L-carnitine and mildronate improves endothelial function and decreases mortality in hypertensive Dahl rats.
Reinis Vilskersts, Janis Kuka, Baiba Svalbe, Helena Cirule, Edgars Liepinsh, Ivars Kalvinsh

Pharmacol Rep· December 2011

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Investigation into stereoselective pharmacological activity of phenotropil.
Liga Zvejniece, Baiba Svalbe, Grigory Veinberg, Solveiga Grinberga, Maksims Vorona, Ivars Kalvinsh

Basic Clin Pharmacol Toxicol· November 2011

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Mildronate treatment alters γ-butyrobetaine and l-carnitine concentrations in healthy volunteers.
Edgars Liepinsh, Ilze Konrade, Elina Skapare, Osvalds Pugovics, Solveiga Grinberga, Ivars Kalvinsh

J Pharm Pharmacol· September 2011

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Correction of glycaemia and GLUT1 level by mildronate in rat streptozotocin diabetes mellitus model.
Jelizaveta Sokolovska, Sergejs Isajevs, Olga Sugoka, Jelena Sharipova, Lasma Lauberte, Ivars Kalvinsh

Cell Biochem Funct· May 2011

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Neuroprotective properties of mildronate, a small molecule, in a rat model of Parkinson's disease.
Vija Z Klusa, Sergejs Isajevs, Darja Svirina, Jolanta Pupure, Ulrika Beitnere, Ivars Kalvinsh

Int J Mol Sci· November 2010

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Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.
Mette K Christensen, Kamille D Erichsen, Christina Trojel-Hansen, Jette Tjørnelund, Søren J Nielsen, Ivars Kalvinsh

J Med Chem· October 2010

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Mildronate exerts acute anticonvulsant and antihypnotic effects.
Liga Zvejniece, Baiba Svalbe, Marina Makrecka, Edgars Liepinsh, Ivars Kalvinsh

Behav Pharmacol· September 2010

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Effects of lycopene, indole-3-carbinol, and luteolin on nitric oxide production and iNOS expression are organ-specific in rats.
Evita Rostoka, Sergejs Isajevs, Larisa Baumane, Aija Line, Karina Silina, Ivars Kalvinsh

Arh Hig Rada Toksikol· September 2010

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Influence of metformin on GLUT1 gene and protein expression in rat streptozotocin diabetes mellitus model.
Jelizaveta Sokolovska, Sergejs Isajevs, Olga Sugoka, Jelena Sharipova, Lasma Lauberte, Ivars Kalvinsh

Arch Physiol Biochem· July 2010

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Effects of kaempferol and myricetin on inducible nitric oxide synthase expression and nitric oxide production in rats.
Evita Rostoka, Larisa Baumane, Sergejs Isajevs, Aija Line, Maija Dzintare, Ivars Kalvinsh

Basic Clin Pharmacol Toxicol· June 2010

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Neuroprotective properties of mildronate, a mitochondria-targeted small molecule.
Jolanta Pupure, Sergejs Isajevs, Elina Skapare, Juris Rumaks, Simons Svirskis, Ivars Kalvinsh

Neurosci Lett· February 2010

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Effects of long-term mildronate treatment on cardiac and liver functions in rats.
Edgars Liepinsh, Janis Kuka, Baiba Svalbe, Reinis Vilskersts, Elina Skapare, Ivars Kalvinsh

Basic Clin Pharmacol Toxicol· December 2009

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Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism.
Kristaps Jaudzems, Janis Kuka, Aleksandrs Gutsaits, Kirils Zinovjevs, Ivars Kalvinsh

J Enzyme Inhib Med Chem· December 2009

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