Publications by authors named "JN Andersen"

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Tumor suppressor collateral damage screens reveal mRNA homeostasis protein HBS1L as a novel vulnerability in ch9p21 driven FOCAD deleted cancer.
Hongxiang Zhang, Matthew R Tonini, Lauren Catherine M Martires, Helena N Jenkins, Charlotte B Pratt, Jannik N Andersen

Biochim Biophys Acta Mol Cell Res· January 2026

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TNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy.
Leanne G Ahronian, Soumyadip Sahu, Minjie Zhang, Ayushi S Patel, Ke Geng, Jannik N Andersen

Cancer Res· October 2025

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CRISPR Screens Identify POLB as a Synthetic Lethal Enhancer of PARP Inhibition Exclusively in BRCA-Mutated Tumors.
Katherine Lazarides, Justin L Engel, Michele Meseonznik, Tianshu Feng, Ashley H Choi, Jannik N Andersen

Mol Cancer Ther· September 2025

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Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor.
Scott Throner, Tianshu Feng, Jannik N Andersen, Madhavi Bandi, Justin L Engel

Bioorg Med Chem Lett· August 2025

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Characterization of TNG348: A Selective, Allosteric USP1 Inhibitor That Synergizes with PARP Inhibitors in Tumors with Homologous Recombination Deficiency.
Antoine Simoneau, Charlotte B Pratt, Hsin-Jung Wu, Shreya S Rajeswaran, Charlotte Grace Comer, Jannik N Andersen

Mol Cancer Ther· May 2025

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LIG1 Is a Synthetic Lethal Target in BRCA1 Mutant Cancers.
Lauren Catherine M Martires, Leanne G Ahronian, Charlotte B Pratt, Nikitha M Das, Xiaobin Zhang, Jannik N Andersen

Mol Cancer Ther· April 2025

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Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer.
Antoine Simoneau, Justin L Engel, Madhavi Bandi, Katherine Lazarides, Shangtao Liu, Jannik N Andersen

Mol Cancer Ther· February 2023

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VRK1 Is a Synthetic-Lethal Target in VRK2-Deficient Glioblastoma.
Julie A Shields, Samuel R Meier, Madhavi Bandi, Erin E Mulkearns-Hubert, Nicole Hajdari, Jannik N Andersen

Cancer Res· November 2022

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Water Chemistry beneath Graphene: Condensation of a Dense OH-HO Phase under Graphene.
Elin Grånäs, Ulrike A Schröder, Mohammad A Arman, Mie Andersen, Timm Gerber, Jesper N Andersen

J Phys Chem C Nanomater Interfaces· March 2022

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Design of BET Inhibitor Bottlebrush Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities.
Farrukh Vohidov, Jannik N Andersen, Kyriakos D Economides, Michail V Shipitsin, Olga Burenkova

J Am Chem Soc· March 2021

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Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs.
Matthew R Golder, Jenny Liu, Jannik N Andersen, Michail V Shipitsin, Farrukh Vohidov

Nat Biomed Eng· November 2018

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Publisher Correction: Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs.
Matthew R Golder, Jenny Liu, Jannik N Andersen, Michail V Shipitsin, Farrukh Vohidov

Nat Biomed Eng· September 2018

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Cross-talk between chromatin acetylation and SUMOylation of tripartite motif-containing protein 24 (TRIM24) impacts cell adhesion.
Srikanth Appikonda, Kaushik N Thakkar, Parantu K Shah, Sharon Y R Dent, Jannik N Andersen

J Biol Chem· May 2018

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Sonogashira cross-coupling over Au(1 1 1): from UHV to ambient pressure.
N Johansson, S Sisodiya, P Shayesteh, S Chaudhary, J N Andersen

J Phys Condens Matter· November 2017

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Ambient pressure phase transitions over Ir(1 1 1): at the onset of CO oxidation.
N Johansson, M Andersen, Y Monya, J N Andersen, H Kondoh

J Phys Condens Matter· November 2017

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Motor Skills and Exercise Capacity Are Associated with Objective Measures of Cognitive Functions and Academic Performance in Preadolescent Children.
Svend Sparre Geertsen, Richard Thomas, Malte Nejst Larsen, Ida Marie Dahn, Josefine Needham Andersen

PLoS One· August 2017

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TRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development.
Patrycja Czerwińska, Parantu K Shah, Katarzyna Tomczak, Marta Klimczak, Sylwia Mazurek, Jannik N Andersen

Oncotarget· January 2017

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The SPECIES beamline at the MAX IV Laboratory: a facility for soft X-ray RIXS and APXPS.
Samuli Urpelainen, Conny Såthe, Walan Grizolli, Marcus Agåker, Ashley R Head, Jesper N Andersen

J Synchrotron Radiat· January 2017

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Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.
Bryan Severyn, Thi Nguyen, Michael D Altman, Lixia Li, Kumiko Nagashima, Jannik N Andersen

J Biomol Screen· October 2016

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Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
Wylie S Palmer, Guillaume Poncet-Montange, Gang Liu, Alessia Petrocchi, Naphtali Reyna, Jannik N Andersen

J Med Chem· February 2016

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The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.
Bhavatarini Vangamudi, Thomas A Paul, Parantu K Shah, Maria Kost-Alimova, Lisa Nottebaum, Jannik N Andersen

Cancer Res· September 2015

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Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery.
Yanai Zhan, Maria Kost-Alimova, Xi Shi, Elisabetta Leo, Jennifer P Bardenhagen, Jannik N Andersen

Epigenetics Chromatin· September 2015

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Manipulating the dynamics of self-propelled gallium droplets by gold nanoparticles and nanoscale surface morphology.
Alexei A Zakharov, Erik Mårsell, Emelie Hilner, Rainer Timm, Jesper N Andersen

ACS Nano· May 2015

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Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
Guillaume Poncet-Montange, Yanai Zhan, Jennifer P Bardenhagen, Alessia Petrocchi, Elisabetta Leo, Jannik N Andersen

Biochem J· March 2015

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Editorial.
Maciej Wiznerowicz, Parantu K Shah, Jannik N Andersen

Contemp Oncol (Pozn)· January 2015

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