Publications by authors named "Jack Scott"

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Individually Ventilated Cages Severely Attenuate Inter-Cage Ultrasonic Vocalizations in Rats.
K Jack Scott, David K Bilkey

J Appl Anim Welf Sci· September 2025

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Normative Performance Functions for the Modified Connected Speech Test.
Yu-Ying Sung, Arman Hassanpour, Paula Folkeard, Ingrid S Johnsrude, Jack M Scott

Am J Audiol· September 2025

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Maternal immune activation alters bout structure of rat 50-kHz ultrasonic vocalizations.
K Jack Scott, Lucinda J Speers, David K Bilkey

Behav Brain Res· June 2025

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Developmental dynamics of marmoset prefrontal cortical SST and PV interneuron networks highlight primate-specific features.
Nafiseh S Hosseini Fin, Adrian Yip, Jack T Scott, Leon Teo, Jihane Homman-Ludiye

Development· May 2025

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CalliCog is an open-source cognitive neuroscience toolkit for freely behaving nonhuman primates.
Jack T Scott, Bruno L Mendivez Vasquez, Brian J Stewart, Dylan D Panacheril, Darren K J Rajit

Cell Rep Methods· May 2025

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Sex-dependent effects of rat maternal immune activation on motor function in offspring of poly I:C treated rats.
K Jack Scott, David K Bilkey

Behav Brain Res· March 2025

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Discovery of sulfone containing metallo-β-lactamase inhibitors with reduced bacterial cell efflux and histamine release issues.
Frank Bennett, Yuhua Huang, Shuzhi Dong, Jinlong Jiang, David Hunter, Jack D Scott

Bioorg Med Chem Lett· December 2024

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an open-source cognitive neuroscience toolkit for freely behaving nonhuman primates.
Jack T Scott, Bruno L Mendivez Vasquez, Brian J Stewart, Dylan D Panacheril, Darren K J Rajit

bioRxiv· November 2024

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Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.
Shuzhi Dong, Zhiqiang Zhao, Haiqun Tang, Guoqing Li, Jianping Pan, Scott R Pollack, Jack D Scott

J Med Chem· March 2024

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Utilizing synthetic training data for the supervised classification of rat ultrasonic vocalizations.
K Jack Scott, Lucinda J Speers, David K Bilkey

J Acoust Soc Am· January 2024

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Synthesis of DNA-Encoded Macrocyclic Peptides via Nitrile-Aminothiol Click Reaction.
Lijun Fan, Yang Yu, Charles Jayne, John R Frost, Jack D Scott

Org Lett· November 2023

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Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.
David A Candito, Vladimir Simov, Anmol Gulati, Solomon Kattar, Ryan W Chau, Jack D Scott

J Med Chem· December 2022

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Modelling behaviors relevant to brain disorders in the nonhuman primate: Are we there yet?
Jack T Scott, James A Bourne

Prog Neurobiol· January 2022

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Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors.
Anmol Gulati, Charles S Yeung, Blair Lapointe, Solomon D Kattar, Hakan Gunaydin, Jack D Scott

RSC Med Chem· July 2021

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Development of DNA-compatible hydroxycarbonylation reactions using chloroform as a source of carbon monoxide.
Wentao Liu, Wei Huang, Qian Lin, Mei-Hsuan Tsai, Rui Zhang, Jack D Scott

Bioorg Med Chem· May 2021

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An Innovative Clinical Skills "Boot Camp" for Dental Medicine Residents.
Jenny Castillo, Jared Kutzin, Kathleen Agoglia, Patricia Janicke, Zachary Milligan, Jack Scott

J Med Educ Curric Dev· May 2017

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Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity.
Jack D Scott, Duane E DeMong, Thomas J Greshock, Kallol Basu, Xing Dai

J Med Chem· April 2017

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Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)-A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer's Disease.
Jack D Scott, Sarah W Li, Andrew P J Brunskill, Xia Chen, Kathleen Cox

J Med Chem· December 2016

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The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer's disease patients.
Matthew E Kennedy, Andrew W Stamford, Xia Chen, Kathleen Cox, Jared N Cumming, Jack D Scott

Sci Transl Med· November 2016

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Using modeling and rehearsal to teach fire safety to children with autism.
David Garcia, Charles Dukes, Michael P Brady, Jack Scott, Cynthia L Wilson

J Appl Behav Anal· September 2016

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Road Map for Opioid Management in the Inpatient Setting: A Structured Approach to Opioid Selection and Titration.
Paula Lester, Rochelle Remolana, Sartaj Sandhu, Jack Scott

MedEdPORTAL· September 2016

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MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition.
Matthew J Fell, Christian Mirescu, Kallol Basu, Boonlert Cheewatrakoolpong, Duane E DeMong, Jack D Scott

J Pharmacol Exp Ther· December 2015

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Tinnitus and hyperacusis in autism spectrum disorders with emphasis on high functioning individuals diagnosed with Asperger's Syndrome.
Ali A Danesh, Dustin Lang, Wafaa Kaf, William D Andreassen, Jack Scott

Int J Pediatr Otorhinolaryngol· October 2015

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Characterization of a novel vasopressin V1b receptor antagonist, V1B-30N, in animal models of anxiety-like and depression-like behavior.
Robert A Hodgson, Deborra Mullins, Sherry X Lu, Mario Guzzi, Xiaoping Zhang, Jack D Scott

Eur J Pharmacol· May 2014

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Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS Aβ Reduction.
Andrew W Stamford, Jack D Scott, Sarah W Li, Suresh Babu, Dawit Tadesse

ACS Med Chem Lett· November 2012

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